Entrez Gene

Basic Information
Gene ID	1364
Name	CLDN4

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
The somatic mutations from COSMIC database
c.558A>C; p.P186P; 7:73831759-73831759	thyroid	other; neoplasm	Substitution - coding silent
c.558A>C; p.P186P; 7:73831759-73831759	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.532delG; p.L180fs*>30; 7:73831733-73831733	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.532delG; p.L180fs*>30; 7:73831733-73831733	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.532delG; p.L180fs*>30; 7:73831733-73831733	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.555T>G; p.C185W; 7:73831756-73831756	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.202G>A; p.D68N; 7:73831403-73831403	skin	malignant_melanoma	Substitution - Missense
c.70T>C; p.C24R; 7:73831271-73831271	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.206C>T; p.S69L; 7:73831407-73831407	skin	malignant_melanoma	Substitution - Missense
c.18A>G; p.L6L; 7:73831219-73831219	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.162C>T; p.C54C; 7:73831363-73831363	central_nervous_system; brain	glioma	Substitution - coding silent
c.421C>T; p.H141Y; 7:73831622-73831622	skin	malignant_melanoma	Substitution - Missense
c.267C>A; p.I89I; 7:73831468-73831468	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.267C>A; p.I89I; 7:73831468-73831468	breast	carcinoma	Substitution - coding silent
c.338C>T; p.A113V; 7:73831539-73831539	skin	malignant_melanoma	Substitution - Missense
c.488C>T; p.S163L; 7:73831689-73831689	urinary_tract; bladder	carcinoma	Substitution - Missense
c.315C>G; p.T105T; 7:73831516-73831516	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.176C>T; p.T59I; 7:73831377-73831377	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.416C>T; p.T139M; 7:73831617-73831617	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.128C>T; p.S43L; 7:73831329-73831329	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.520C>T; p.L174L; 7:73831721-73831721	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.8C>T; p.S3F; 7:73831209-73831209	skin	malignant_melanoma	Substitution - Missense
c.8C>T; p.S3F; 7:73831209-73831209	skin	malignant_melanoma	Substitution - Missense
c.379T>A; p.L127M; 7:73831580-73831580	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.307A>G; p.K103E; 7:73831508-73831508	thyroid	other; neoplasm	Substitution - Missense
c.94G>A; p.V32M; 7:73831295-73831295	skin	malignant_melanoma	Substitution - Missense
c.448C>T; p.P150S; 7:73831649-73831649	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.135C>T; p.T45T; 7:73831336-73831336	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.506C>T; p.A169V; 7:73831707-73831707	skin	malignant_melanoma	Substitution - Missense
c.481G>T; p.G161C; 7:73831682-73831682	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.41C>T; p.A14V; 7:73831242-73831242	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.302G>A; p.G101E; 7:73831503-73831503	skin	malignant_melanoma	Substitution - Missense
c.428T>C; p.I143T; 7:73831629-73831629	breast	carcinoma	Substitution - Missense
c.581C>T; p.S194F; 7:73831782-73831782	skin	malignant_melanoma	Substitution - Missense
c.404C>T; p.P135L; 7:73831605-73831605	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.429C>T; p.I143I; 7:73831630-73831630	skin	malignant_melanoma	Substitution - coding silent
c.236C>T; p.A79V; 7:73831437-73831437	skin	malignant_melanoma	Substitution - Missense
c.308A>C; p.K103T; 7:73831509-73831509	breast	carcinoma	Substitution - Missense

The somatic mutations from COSMIC database