Entrez Gene

Basic Information
Gene ID	1235
Name	CCR6

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
The somatic mutations from COSMIC database
c.36C>T; p.F12F; 6:167136266-167136266	oesophagus	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.37G>T; p.D13Y; 6:167136267-167136267	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1110G>A; p.S370S; 6:167137340-167137340	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.469C>T; p.R157*; 6:167136699-167136699	skin	malignant_melanoma	Substitution - Nonsense
c.537C>T; p.S179S; 6:167136767-167136767	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.240G>T; p.M80I; 6:167136470-167136470	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.969C>G; p.F323L; 6:167137199-167137199	breast	carcinoma	Substitution - Missense
c.25A>G; p.S9G; 6:167136255-167136255	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.25A>G; p.S9G; 6:167136255-167136255	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.25A>G; p.S9G; 6:167136255-167136255	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.721T>A; p.L241M; 6:167136951-167136951	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.721T>A; p.L241M; 6:167136951-167136951	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.721T>A; p.L241M; 6:167136951-167136951	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.721T>A; p.L241M; 6:167136951-167136951	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.721T>A; p.L241M; 6:167136951-167136951	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.721T>A; p.L241M; 6:167136951-167136951	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.721T>A; p.L241M; 6:167136951-167136951	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.721T>A; p.L241M; 6:167136951-167136951	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.721T>A; p.L241M; 6:167136951-167136951	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.721T>A; p.L241M; 6:167136951-167136951	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.721T>A; p.L241M; 6:167136951-167136951	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.474C>T; p.S158S; 6:167136704-167136704	skin	malignant_melanoma	Substitution - coding silent
c.546T>G; p.T182T; 6:167136776-167136776	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.427C>T; p.R143W; 6:167136657-167136657	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.780G>T; p.V260V; 6:167137010-167137010	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.878T>G; p.L293R; 6:167137108-167137108	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.759C>G; p.I253M; 6:167136989-167136989	ovary	other; neoplasm	Substitution - Missense
c.28G>A; p.D10N; 6:167136258-167136258	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.28G>A; p.D10N; 6:167136258-167136258	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.759C>G; p.I253M; 6:167136989-167136989	ovary	other; neoplasm	Substitution - Missense
c.1113C>T; p.S371S; 6:167137343-167137343	skin	malignant_melanoma	Substitution - coding silent
c.857G>A; p.R286Q; 6:167137087-167137087	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.174C>T; p.V58V; 6:167136404-167136404	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.498C>A; p.I166I; 6:167136728-167136728	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.604C>A; p.Q202K; 6:167136834-167136834	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1005G>A; p.W335*; 6:167137235-167137235	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.782T>C; p.L261P; 6:167137012-167137012	urinary_tract; bladder	carcinoma	Substitution - Missense
c.782T>C; p.L261P; 6:167137012-167137012	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.705G>A; p.T235T; 6:167136935-167136935	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.891G>A; p.T297T; 6:167137121-167137121	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.372C>A; p.I124I; 6:167136602-167136602	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.372C>A; p.I124I; 6:167136602-167136602	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.539G>A; p.S180N; 6:167136769-167136769	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.536C>T; p.S179F; 6:167136766-167136766	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1077G>A; p.Q359Q; 6:167137307-167137307	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1077G>A; p.Q359Q; 6:167137307-167137307	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.718A>T; p.T240S; 6:167136948-167136948	pancreas	carcinoma	Substitution - Missense
c.53_54insT; p.V20fs*11; 6:167136283-167136284	liver	carcinoma; hepatocellular_carcinoma	Insertion - Frameshift
c.188G>T; p.G63V; 6:167136418-167136418	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.506T>C; p.L169P; 6:167136736-167136736	prostate	carcinoma	Substitution - Missense
c.1028C>T; p.S343F; 6:167137258-167137258	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.763G>C; p.V255L; 6:167136993-167136993	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1016_1017GG>AA; p.R339K; 6:167137246-167137247	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1016G>T; p.R339M; 6:167137246-167137246	oesophagus	carcinoma	Substitution - Missense
c.531C>A; p.I177I; 6:167136761-167136761	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.150G>A; p.P50P; 6:167136380-167136380	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.470G>A; p.R157Q; 6:167136700-167136700	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.199G>T; p.V67L; 6:167136429-167136429	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.663T>C; p.F221F; 6:167136893-167136893	skin	malignant_melanoma	Substitution - coding silent
c.110C>T; p.S37F; 6:167136340-167136340	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.199G>A; p.V67M; 6:167136429-167136429	skin	malignant_melanoma	Substitution - Missense
c.690G>A; p.M230I; 6:167136920-167136920	skin	malignant_melanoma	Substitution - Missense
c.859T>C; p.S287P; 6:167137089-167137089	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.830C>T; p.T277M; 6:167137060-167137060	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1110G>T; p.S370S; 6:167137340-167137340	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.399G>T; p.M133I; 6:167136629-167136629	oesophagus	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1072C>T; p.R358W; 6:167137302-167137302	skin	malignant_melanoma	Substitution - Missense
c.111C>T; p.S37S; 6:167136341-167136341	skin	malignant_melanoma	Substitution - coding silent
c.149C>T; p.P50L; 6:167136379-167136379	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.918C>T; p.F306F; 6:167137148-167137148	skin	malignant_melanoma	Substitution - coding silent
c.458C>T; p.S153L; 6:167136688-167136688	liver	carcinoma	Substitution - Missense
c.1089C>A; p.T363T; 6:167137319-167137319	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.747G>A; p.R249R; 6:167136977-167136977	breast	carcinoma	Substitution - coding silent
c.159C>T; p.Y53Y; 6:167136389-167136389	skin	malignant_melanoma	Substitution - coding silent
c.1017G>A; p.R339R; 6:167137247-167137247	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.57T>C; p.F19F; 6:167136287-167136287	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.266C>T; p.A89V; 6:167136496-167136496	skin	malignant_melanoma	Substitution - Missense
c.435C>T; p.I145I; 6:167136665-167136665	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.132C>A; p.F44L; 6:167136362-167136362	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.630G>A; p.W210*; 6:167136860-167136860	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.583G>A; p.D195N; 6:167136813-167136813	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.583G>A; p.D195N; 6:167136813-167136813	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.518G>A; p.G173E; 6:167136748-167136748	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.943C>T; p.L315F; 6:167137173-167137173	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1048G>A; p.G350R; 6:167137278-167137278	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1048G>A; p.G350R; 6:167137278-167137278	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1107G>T; p.A369A; 6:167137337-167137337	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.701A>G; p.Y234C; 6:167136931-167136931	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.127C>A; p.Q43K; 6:167136357-167136357	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.927C>T; p.C309C; 6:167137157-167137157	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1045G>A; p.A349T; 6:167137275-167137275	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.27C>T; p.S9S; 6:167136257-167136257	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.856C>T; p.R286*; 6:167137086-167137086	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Nonsense

The somatic mutations from COSMIC database