Entrez Gene

Basic Information
Gene ID	1112
Name	FOXN3

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
The somatic mutations from COSMIC database
c.574G>C; p.D192H; 14:89350778-89350778	liver	carcinoma	Substitution - Missense
c.788G>A; p.R263Q; 14:89180764-89180764	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1024G>A; p.D342N; 14:89162797-89162797	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1235C>T; p.T412I; 14:89162586-89162586	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.808C>T; p.R270W; 14:89180744-89180744	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.445C>T; p.P149S; 14:89412032-89412032	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.615G>C; p.K205N; 14:89350737-89350737	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.1152G>A; p.K384K; 14:89162669-89162669	skin	malignant_melanoma	Substitution - coding silent
c.1152G>T; p.K384N; 14:89162669-89162669	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1112C>T; p.T371M; 14:89162709-89162709	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1007C>T; p.S336F; 14:89162814-89162814	skin	malignant_melanoma	Substitution - Missense
c.1007C>T; p.S336F; 14:89162814-89162814	skin	malignant_melanoma	Substitution - Missense
c.1007C>T; p.S336F; 14:89162814-89162814	skin	malignant_melanoma	Substitution - Missense
c.1240C>T; p.P414S; 14:89162581-89162581	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.793C>G; p.L265V; 14:89180759-89180759	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.348delC; p.Y117fs*21; 14:89412129-89412129	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.219G>A; p.L73L; 14:89412258-89412258	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1193A>T; p.K398M; 14:89162628-89162628	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1087C>T; p.R363W; 14:89162734-89162734	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.1272C>A; p.P424P; 14:89162549-89162549	skin	malignant_melanoma	Substitution - coding silent
c.1364C>T; p.T455M; 14:89162457-89162457	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.73T>C; p.C25R; 14:89412404-89412404	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1354A>C; p.T452P; 14:89162467-89162467	kidney	other; neoplasm	Substitution - Missense
c.871C>T; p.R291W; 14:89162950-89162950	liver	carcinoma	Substitution - Missense
c.871C>T; p.R291W; 14:89162950-89162950	liver	carcinoma	Substitution - Missense
c.316G>A; p.D106N; 14:89412161-89412161	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.36A>C; p.E12D; 14:89412441-89412441	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1148C>T; p.P383L; 14:89162673-89162673	skin	malignant_melanoma	Substitution - Missense
c.1108G>A; p.D370N; 14:89162713-89162713	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.287_288insC; p.S97fs*6; 14:89412189-89412190	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.287_288insC; p.S97fs*6; 14:89412189-89412190	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.236C>T; p.S79L; 14:89412241-89412241	skin	malignant_melanoma	Substitution - Missense
c.48T>G; p.I16M; 14:89412429-89412429	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1338C>T; p.S446S; 14:89162483-89162483	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1355C>A; p.T452N; 14:89162466-89162466	kidney	other; neoplasm	Substitution - Missense
c.1157C>A; p.S386Y; 14:89162664-89162664	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.121C>T; p.L41F; 14:89412356-89412356	skin	malignant_melanoma	Substitution - Missense
c.1074C>T; p.S358S; 14:89162747-89162747	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.402C>T; p.R134R; 14:89412075-89412075	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.282C>T; p.T94T; 14:89412195-89412195	skin	malignant_melanoma	Substitution - coding silent
c.543+1G>A; p.?; 14:89411933-89411933	large_intestine; caecum	carcinoma; adenocarcinoma	Unknown
c.953C>A; p.A318D; 14:89162868-89162868	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1014_1016delCTC; p.S339delS; 14:89162805-89162807	skin	malignant_melanoma	Deletion - In frame
c.1297G>A; p.E433K; 14:89162524-89162524	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1014_1016delCTC; p.S339delS; 14:89162805-89162807	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - In frame
c.1122C>T; p.D374D; 14:89162699-89162699	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1014_1016delCTC; p.S339delS; 14:89162805-89162807	skin	malignant_melanoma	Deletion - In frame
c.1014_1016delCTC; p.S339delS; 14:89162805-89162807	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - In frame
c.257C>T; p.P86L; 14:89412220-89412220	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.560C>T; p.S187L; 14:89350792-89350792	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.484G>C; p.V162L; 14:89411993-89411993	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.717C>T; p.F239F; 14:89280978-89280978	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1219A>G; p.K407E; 14:89162602-89162602	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.447G>A; p.P149P; 14:89412030-89412030	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.931G>A; p.E311K; 14:89162890-89162890	skin	malignant_melanoma	Substitution - Missense
c.237G>A; p.S79S; 14:89412240-89412240	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.237G>A; p.S79S; 14:89412240-89412240	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.1069G>C; p.G357R; 14:89162752-89162752	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1320C>T; p.H440H; 14:89162501-89162501	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1014C>T; p.S338S; 14:89162807-89162807	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.500C>T; p.S167L; 14:89411977-89411977	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.827C>T; p.P276L; 14:89180725-89180725	skin	malignant_melanoma	Substitution - Missense
c.1014C>A; p.S338S; 14:89162807-89162807	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.296C>T; p.A99V; 14:89412181-89412181	breast	carcinoma	Substitution - Missense
c.1206C>T; p.F402F; 14:89162615-89162615	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.580G>C; p.E194Q; 14:89350772-89350772	urinary_tract; bladder	carcinoma	Substitution - Missense
c.391C>T; p.P131S; 14:89412086-89412086	skin	malignant_melanoma	Substitution - Missense
c.1273G>A; p.E425K; 14:89162548-89162548	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1151A>C; p.K384T; 14:89162670-89162670	pancreas	carcinoma	Substitution - Missense
c.261C>A; p.V87V; 14:89412216-89412216	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.126C>A; p.D42E; 14:89412351-89412351	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1091G>A; p.S364N; 14:89162730-89162730	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.776G>T; p.R259L; 14:89180776-89180776	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.658A>G; p.T220A; 14:89350694-89350694	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.736C>A; p.L246I; 14:89280959-89280959	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.668A>G; p.Q223R; 14:89350684-89350684	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.842C>T; p.A281V; 14:89180710-89180710	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1195C>T; p.R399C; 14:89162626-89162626	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.842C>T; p.A281V; 14:89180710-89180710	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.296C>A; p.A99D; 14:89412181-89412181	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.314A>T; p.Y105F; 14:89412163-89412163	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.287delC; p.P96fs*42; 14:89412190-89412190	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.287delC; p.P96fs*42; 14:89412190-89412190	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.287delC; p.P96fs*42; 14:89412190-89412190	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.287delC; p.P96fs*42; 14:89412190-89412190	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.287delC; p.P96fs*42; 14:89412190-89412190	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.287delC; p.P96fs*42; 14:89412190-89412190	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.400C>T; p.R134C; 14:89412077-89412077	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.400C>T; p.R134C; 14:89412077-89412077	stomach	carcinoma; adenocarcinoma	Substitution - Missense

The somatic mutations from COSMIC database