Entrez Gene

Basic Information
Gene ID	10979
Name	FERMT2

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
The somatic mutations from COSMIC database
c.1823G>A; p.R608H; 14:52859619-52859619	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.817C>T; p.R273*; 14:52881074-52881074	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1020C>G; p.D340E; 14:52875301-52875301	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1192A>T; p.T398S; 14:52872880-52872880	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.210T>C; p.T70T; 14:52919304-52919304	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1398C>T; p.H466H; 14:52864605-52864605	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - coding silent
c.1607C>T; p.T536I; 14:52860461-52860461	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.843T>G; p.D281E; 14:52881048-52881048	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.315C>A; p.N105K; 14:52919199-52919199	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.460A>C; p.K154Q; 14:52893359-52893359	liver	carcinoma	Substitution - Missense
c.456G>A; p.K152K; 14:52893363-52893363	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.452A>C; p.K151T; 14:52893367-52893367	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.607C>A; p.P203T; 14:52881389-52881389	liver	carcinoma	Substitution - Missense
c.1375_1376insCGTTGTG; p.D459fs*3; 14:52864751-52864752	liver	carcinoma	Insertion - Frameshift
c.1251A>G; p.P417P; 14:52872821-52872821	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.106A>G; p.T36A; 14:52950463-52950463	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1994A>G; p.E665G; 14:52858426-52858426	large_intestine; colon	carcinoma	Substitution - Missense
c.146T>G; p.V49G; 14:52950423-52950423	breast	carcinoma	Substitution - Missense
c.1994A>G; p.E665G; 14:52858426-52858426	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.404C>T; p.P135L; 14:52893415-52893415	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1316T>G; p.F439C; 14:52864811-52864811	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1365G>A; p.W455*; 14:52864762-52864762	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.358T>C; p.F120L; 14:52919156-52919156	central_nervous_system; brain	glioma	Substitution - Missense
c.681C>A; p.I227I; 14:52881315-52881315	pancreas	carcinoma	Substitution - coding silent
c.1040A>G; p.D347G; 14:52875281-52875281	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.167A>T; p.K56I; 14:52919347-52919347	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.299G>T; p.R100L; 14:52919215-52919215	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1863C>A; p.I621I; 14:52859579-52859579	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1369C>T; p.R457C; 14:52864758-52864758	endometrium	carcinoma; serous_carcinoma	Substitution - Missense
c.178G>A; p.D60N; 14:52919336-52919336	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.178G>A; p.D60N; 14:52919336-52919336	lung	carcinoma; bronchioloalveolar_adenocarcinoma	Substitution - Missense
c.420C>T; p.L140L; 14:52893399-52893399	skin	malignant_melanoma	Substitution - coding silent
c.2037G>T; p.W679C; 14:52858383-52858383	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.41C>T; p.A14V; 14:52950528-52950528	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.598C>T; p.P200S; 14:52881398-52881398	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1086G>A; p.T362T; 14:52875235-52875235	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1624G>T; p.A542S; 14:52860444-52860444	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.4G>A; p.A2T; 14:52950565-52950565	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1477C>A; p.L493I; 14:52864526-52864526	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.156C>A; p.L52L; 14:52950413-52950413	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1879G>C; p.E627Q; 14:52858541-52858541	breast	carcinoma	Substitution - Missense
c.1294G>A; p.V432I; 14:52864833-52864833	upper_aerodigestive_tract; mouth	carcinoma	Substitution - Missense
c.1294G>A; p.V432I; 14:52864833-52864833	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.724C>T; p.L242F; 14:52881272-52881272	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1362C>T; p.I454I; 14:52864765-52864765	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1738G>A; p.G580S; 14:52859704-52859704	skin	malignant_melanoma	Substitution - Missense
c.1889A>T; p.D630V; 14:52858531-52858531	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.409G>A; p.E137K; 14:52893410-52893410	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1329C>A; p.L443L; 14:52864798-52864798	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.157+7A>T; p.?; 14:52950405-52950405	prostate	carcinoma	Unknown
c.1138A>G; p.K380E; 14:52874187-52874187	skin	malignant_melanoma	Substitution - Missense
c.1746delA; p.E583fs*11; 14:52859696-52859696	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1981A>C; p.K661Q; 14:52858439-52858439	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1467T>G; p.V489V; 14:52864536-52864536	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1326A>T; p.K442N; 14:52864801-52864801	bone; pelvis	chondrosarcoma	Substitution - Missense
c.1166T>C; p.L389P; 14:52872906-52872906	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.643G>C; p.E215Q; 14:52881353-52881353	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1974A>G; p.T658T; 14:52858446-52858446	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.797A>G; p.E266G; 14:52881094-52881094	skin	malignant_melanoma	Substitution - Missense
c.1708A>G; p.I570V; 14:52860360-52860360	liver	carcinoma	Substitution - Missense
c.142C>T; p.L48L; 14:52950427-52950427	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.71T>C; p.V24A; 14:52950498-52950498	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1783C>T; p.R595W; 14:52859659-52859659	endometrium	carcinoma; serous_carcinoma	Substitution - Missense
c.1783C>T; p.R595W; 14:52859659-52859659	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.485A>G; p.E162G; 14:52893334-52893334	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.1244G>A; p.G415D; 14:52872828-52872828	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1646T>A; p.M549K; 14:52860422-52860422	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.477T>C; p.S159S; 14:52893342-52893342	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.345C>A; p.F115L; 14:52919169-52919169	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.345C>A; p.F115L; 14:52919169-52919169	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.345C>A; p.F115L; 14:52919169-52919169	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.345C>A; p.F115L; 14:52919169-52919169	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1048C>T; p.L350F; 14:52875273-52875273	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1975C>T; p.R659C; 14:52858445-52858445	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1281A>C; p.E427D; 14:52864846-52864846	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.795G>A; p.K265K; 14:52881096-52881096	skin	malignant_melanoma	Substitution - coding silent
c.1482C>A; p.S494S; 14:52864521-52864521	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.455delA; p.K152fs*4; 14:52893364-52893364	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.456G>AG; p.K153fs*5; 14:52893363-52893363	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; Burkitt_lymphoma	Complex - frameshift
c.324T>C; p.Y108Y; 14:52919190-52919190	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.1574G>A; p.R525H; 14:52864429-52864429	pancreas	carcinoma; acinar_carcinoma	Substitution - Missense
c.1574G>A; p.R525H; 14:52864429-52864429	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.166A>G; p.K56E; 14:52919348-52919348	ovary	other; neoplasm	Substitution - Missense
c.139A>C; p.K47Q; 14:52950430-52950430	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1381-3C>T; p.?; 14:52864625-52864625	skin; head_neck	carcinoma; squamous_cell_carcinoma	Unknown
c.1337C>T; p.P446L; 14:52864790-52864790	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.12C>T; p.D4D; 14:52950557-52950557	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.637T>G; p.L213V; 14:52881359-52881359	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1839A>C; p.K613N; 14:52859603-52859603	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.1839A>C; p.K613N; 14:52859603-52859603	liver	carcinoma	Substitution - Missense
c.67C>T; p.H23Y; 14:52950502-52950502	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1742A>C; p.K581T; 14:52859700-52859700	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.873C>A; p.I291I; 14:52878672-52878672	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.2005G>A; p.E669K; 14:52858415-52858415	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1983A>G; p.K661K; 14:52858437-52858437	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1329C>T; p.L443L; 14:52864798-52864798	skin	malignant_melanoma	Substitution - coding silent
c.279C>T; p.T93T; 14:52919235-52919235	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.168delA; p.D57fs*17; 14:52919346-52919346	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.727C>A; p.L243I; 14:52881269-52881269	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.677C>T; p.P226L; 14:52881319-52881319	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1668G>A; p.M556I; 14:52860400-52860400	skin	malignant_melanoma	Substitution - Missense
c.1706G>A; p.G569D; 14:52860362-52860362	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1784G>A; p.R595Q; 14:52859658-52859658	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1451C>T; p.S484F; 14:52864552-52864552	skin; ankle	malignant_melanoma; acral_lentiginous	Substitution - Missense
c.1513C>T; p.P505S; 14:52864490-52864490	breast	carcinoma	Substitution - Missense
c.297C>T; p.L99L; 14:52919217-52919217	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1349G>A; p.G450D; 14:52864778-52864778	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.579T>C; p.Y193Y; 14:52881417-52881417	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.493G>T; p.E165*; 14:52893326-52893326	NS	NS	Substitution - Nonsense
c.527G>A; p.G176E; 14:52881469-52881469	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.967C>G; p.H323D; 14:52875354-52875354	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1797C>T; p.S599S; 14:52859645-52859645	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent

The somatic mutations from COSMIC database