Entrez Gene

Basic Information
Gene ID	10919
Name	EHMT2

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
The somatic mutations from COSMIC database
c.3291C>T; p.Y1097Y; 6:31880834-31880834	skin	malignant_melanoma	Substitution - coding silent
c.2617C>T; p.R873C; 6:31884546-31884546	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2617C>T; p.R873C; 6:31884546-31884546	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.2060C>T; p.T687M; 6:31887053-31887053	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.50C>A; p.A17D; 6:31896982-31896982	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1365+9G>A; p.?; 6:31888590-31888590	liver	carcinoma	Unknown
c.1365+9G>A; p.?; 6:31888590-31888590	liver	carcinoma	Unknown
c.50C>A; p.A17D; 6:31896982-31896982	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.50C>A; p.A17D; 6:31896982-31896982	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.50C>A; p.A17D; 6:31896982-31896982	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.50C>A; p.A17D; 6:31896982-31896982	skin	malignant_melanoma	Substitution - Missense
c.50C>A; p.A17D; 6:31896982-31896982	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.50C>A; p.A17D; 6:31896982-31896982	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.50C>A; p.A17D; 6:31896982-31896982	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.2563delC; p.L855fs*36; 6:31884685-31884685	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1465G>T; p.V489F; 6:31888407-31888407	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Missense
c.2588A>G; p.Y863C; 6:31884660-31884660	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2717A>T; p.K906M; 6:31884446-31884446	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3434G>A; p.R1145Q; 6:31880691-31880691	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.551G>A; p.R184H; 6:31896294-31896294	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2355delG; p.W786fs*15; 6:31885005-31885005	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.995A>C; p.D332A; 6:31889472-31889472	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.338C>A; p.T113K; 6:31896507-31896507	adrenal_gland; adrenal_gland	adrenal_cortical_carcinoma; functioning	Substitution - Missense
c.2536G>T; p.A846S; 6:31884712-31884712	pancreas	carcinoma	Substitution - Missense
c.2699C>T; p.A900V; 6:31884464-31884464	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1193G>A; p.G398E; 6:31888992-31888992	central_nervous_system; brain	glioma	Substitution - Missense
c.169G>A; p.D57N; 6:31896765-31896765	urinary_tract; bladder	carcinoma	Substitution - Missense
c.2592T>G; p.H864Q; 6:31884656-31884656	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.194C>A; p.S65*; 6:31896740-31896740	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.3417C>T; p.F1139F; 6:31880708-31880708	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.586C>A; p.P196T; 6:31892907-31892907	breast	carcinoma	Substitution - Missense
c.1793C>T; p.P598L; 6:31887914-31887914	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2421G>A; p.R807R; 6:31884939-31884939	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.1979A>G; p.Q660R; 6:31887609-31887609	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.2750G>A; p.R917H; 6:31884413-31884413	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2797G>A; p.V933M; 6:31883925-31883925	pancreas	carcinoma; acinar_carcinoma	Substitution - Missense
c.2842G>A; p.E948K; 6:31883880-31883880	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3395G>A; p.R1132Q; 6:31880730-31880730	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1861G>A; p.V621M; 6:31887846-31887846	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1034delA; p.K345fs*9; 6:31889308-31889308	lung	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2181G>A; p.V727V; 6:31886835-31886835	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.67G>T; p.A23S; 6:31896965-31896965	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.980C>T; p.S327L; 6:31889487-31889487	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1455C>T; p.R485R; 6:31888417-31888417	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.3611C>T; p.S1204F; 6:31880106-31880106	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1932G>A; p.R644R; 6:31887656-31887656	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.931G>C; p.E311Q; 6:31889536-31889536	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1635G>T; p.E545D; 6:31888151-31888151	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.3409G>A; p.A1137T; 6:31880716-31880716	lung; middle_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.592C>T; p.P198S; 6:31892901-31892901	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1136C>G; p.S379*; 6:31889049-31889049	urinary_tract; bladder	carcinoma	Substitution - Nonsense
c.1352G>T; p.S451I; 6:31888612-31888612	thyroid	other; neoplasm	Substitution - Missense
c.1670C>T; p.P557L; 6:31888116-31888116	skin	malignant_melanoma	Substitution - Missense
c.2549A>G; p.H850R; 6:31884699-31884699	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2448+1G>A; p.?; 6:31884911-31884911	stomach	carcinoma; adenocarcinoma	Unknown
c.733C>T; p.R245C; 6:31892538-31892538	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.356C>T; p.S119F; 6:31896489-31896489	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.3207G>A; p.G1069G; 6:31881083-31881083	central_nervous_system; brain	glioma	Substitution - coding silent
c.1854T>G; p.L618L; 6:31887853-31887853	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.768C>T; p.P256P; 6:31892503-31892503	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.1971C>A; p.S657S; 6:31887617-31887617	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - coding silent
c.3002G>A; p.R1001Q; 6:31883002-31883002	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2855A>G; p.Y952C; 6:31883867-31883867	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2011+4A>T; p.?; 6:31887573-31887573	prostate	carcinoma	Unknown
c.3394C>T; p.R1132*; 6:31880731-31880731	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1079G>A; p.R360H; 6:31889263-31889263	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.3563G>T; p.R1188L; 6:31880154-31880154	thyroid	carcinoma	Substitution - Missense
c.3404G>A; p.R1135H; 6:31880721-31880721	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.317G>A; p.R106Q; 6:31896617-31896617	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.92G>C; p.R31T; 6:31896940-31896940	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.2865G>A; p.E955E; 6:31883857-31883857	skin	malignant_melanoma	Substitution - coding silent
c.3601G>C; p.E1201Q; 6:31880116-31880116	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1903G>A; p.A635T; 6:31887804-31887804	breast	carcinoma	Substitution - Missense
c.1039C>T; p.R347*; 6:31889303-31889303	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1896G>A; p.L632L; 6:31887811-31887811	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2908C>A; p.H970N; 6:31883814-31883814	skin	malignant_melanoma	Substitution - Missense
c.3629C>T; p.T1210I; 6:31880088-31880088	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.845G>A; p.R282H; 6:31892426-31892426	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.845G>A; p.R282H; 6:31892426-31892426	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.613A>G; p.I205V; 6:31892880-31892880	liver	carcinoma	Substitution - Missense
c.232G>A; p.G78R; 6:31896702-31896702	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.613A>G; p.I205V; 6:31892880-31892880	liver	carcinoma	Substitution - Missense
c.1128G>T; p.V376V; 6:31889057-31889057	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.781G>A; p.E261K; 6:31892490-31892490	cervix	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2674C>T; p.P892S; 6:31884489-31884489	skin	malignant_melanoma	Substitution - Missense
c.2189A>C; p.H730P; 6:31886827-31886827	breast	carcinoma	Substitution - Missense
c.1575T>A; p.S525S; 6:31888211-31888211	skin	malignant_melanoma	Substitution - coding silent
c.3035C>T; p.P1012L; 6:31882969-31882969	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2684C>T; p.S895F; 6:31884479-31884479	skin	malignant_melanoma	Substitution - Missense
c.1552C>T; p.R518C; 6:31888234-31888234	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.2218C>T; p.R740C; 6:31886798-31886798	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1687C>T; p.P563S; 6:31888099-31888099	skin	malignant_melanoma	Substitution - Missense
c.2246A>G; p.E749G; 6:31886678-31886678	kidney	other; neoplasm	Substitution - Missense
c.2113C>T; p.L705L; 6:31887000-31887000	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1888G>A; p.E630K; 6:31887819-31887819	urinary_tract; bladder	carcinoma	Substitution - Missense
c.3499A>C; p.T1167P; 6:31880218-31880218	thyroid	other; neoplasm	Substitution - Missense
c.545G>A; p.R182Q; 6:31896300-31896300	ovary	other; neoplasm	Substitution - Missense
c.1284C>T; p.C428C; 6:31888680-31888680	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.994G>A; p.D332N; 6:31889473-31889473	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.3546T>A; p.I1182I; 6:31880171-31880171	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.3330C>A; p.F1110L; 6:31880795-31880795	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.2818G>A; p.G940S; 6:31883904-31883904	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2061G>A; p.T687T; 6:31887052-31887052	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1471C>A; p.H491N; 6:31888401-31888401	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.930A>G; p.E310E; 6:31889537-31889537	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.2221G>T; p.G741C; 6:31886795-31886795	adrenal_gland; adrenal_gland	adrenal_cortical_carcinoma; functioning	Substitution - Missense
c.663C>A; p.T221T; 6:31892830-31892830	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1348G>A; p.E450K; 6:31888616-31888616	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1983C>T; p.G661G; 6:31887605-31887605	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.2001C>T; p.I667I; 6:31887587-31887587	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.231G>T; p.E77D; 6:31896703-31896703	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1972G>A; p.V658M; 6:31887616-31887616	bone; pelvis	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.1170delG; p.S391fs*79; 6:31889015-31889015	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.3476G>T; p.W1159L; 6:31880241-31880241	cervix	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2909A>C; p.H970P; 6:31883813-31883813	breast	carcinoma	Substitution - Missense
c.79G>C; p.E27Q; 6:31896953-31896953	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.3128A>G; p.Y1043C; 6:31882768-31882768	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2927G>C; p.C976S; 6:31883429-31883429	prostate	carcinoma	Substitution - Missense
c.1687C>G; p.P563A; 6:31888099-31888099	urinary_tract; bladder	carcinoma	Substitution - Missense
c.943G>T; p.E315*; 6:31889524-31889524	oesophagus	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1645C>T; p.P549S; 6:31888141-31888141	skin	malignant_melanoma	Substitution - Missense
c.2647G>C; p.E883Q; 6:31884516-31884516	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.1951C>T; p.P651S; 6:31887637-31887637	skin	malignant_melanoma	Substitution - Missense
c.2196G>T; p.E732D; 6:31886820-31886820	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1252C>T; p.R418*; 6:31888712-31888712	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2551G>T; p.G851W; 6:31884697-31884697	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.647C>T; p.S216L; 6:31892846-31892846	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3424C>T; p.R1142*; 6:31880701-31880701	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2680C>T; p.R894C; 6:31884483-31884483	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2908C>G; p.H970D; 6:31883814-31883814	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1897G>C; p.E633Q; 6:31887810-31887810	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2876C>T; p.T959M; 6:31883846-31883846	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3054C>A; p.N1018K; 6:31882950-31882950	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.2591A>C; p.H864P; 6:31884657-31884657	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.2615C>T; p.S872L; 6:31884548-31884548	skin	malignant_melanoma	Substitution - Missense

The somatic mutations from COSMIC database