Entrez Gene

Basic Information
Gene ID	10857
Name	PGRMC1

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
The somatic mutations from COSMIC database
c.139C>T; p.R47C; 23:119236502-119236502	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.218T>G; p.F73C; 23:119236581-119236581	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.247G>T; p.G83C; 23:119236610-119236610	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.405G>A; p.L135L; 23:119240385-119240385	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.572C>A; p.A191D; 23:119243238-119243238	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.271A>T; p.M91L; 23:119236634-119236634	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; mantle_cell_lymphoma	Substitution - Missense
c.162C>T; p.S54S; 23:119236525-119236525	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.387C>T; p.C129C; 23:119240367-119240367	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.421G>A; p.D141N; 23:119240401-119240401	urinary_tract; bladder	carcinoma	Substitution - Missense
c.421G>A; p.D141N; 23:119240401-119240401	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.70G>A; p.E24K; 23:119236433-119236433	breast	carcinoma	Substitution - Missense
c.156G>T; p.A52A; 23:119236519-119236519	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.504C>A; p.G168G; 23:119243170-119243170	breast	carcinoma	Substitution - coding silent
c.214G>A; p.D72N; 23:119236577-119236577	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.325C>T; p.P109S; 23:119236688-119236688	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.235C>T; p.R79W; 23:119236598-119236598	central_nervous_system; brain	glioma	Substitution - Missense
c.242T>C; p.F81S; 23:119236605-119236605	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.171C>T; p.S57S; 23:119236534-119236534	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - coding silent
c.174C>T; p.D58D; 23:119236537-119236537	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.503G>T; p.G168V; 23:119243169-119243169	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.178G>A; p.D60N; 23:119236541-119236541	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.43G>A; p.D15N; 23:119236406-119236406	skin	malignant_melanoma	Substitution - Missense
c.562G>A; p.D188N; 23:119243228-119243228	breast	carcinoma	Substitution - Missense
c.179A>G; p.D60G; 23:119236542-119236542	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.23C>T; p.A8V; 23:119236386-119236386	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.208C>T; p.R70W; 23:119236571-119236571	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.120C>T; p.F40F; 23:119236483-119236483	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.265A>G; p.I89V; 23:119236628-119236628	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.418G>A; p.D140N; 23:119240398-119240398	skin	malignant_melanoma	Substitution - Missense
c.553G>T; p.E185*; 23:119243219-119243219	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.141C>T; p.R47R; 23:119236504-119236504	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.24G>A; p.A8A; 23:119236387-119236387	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.469G>A; p.E157K; 23:119240449-119240449	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.419A>G; p.D140G; 23:119240399-119240399	stomach	carcinoma; adenocarcinoma	Substitution - Missense

The somatic mutations from COSMIC database