Epithelial-Mesenchymal Transition gene database (dbEMT) Home
dbEMT
dbEMT 2.0
General information | Literature | Expression | lncRNA |Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

10637

Name

LEFTY1

The somatic mutations from COSMIC database

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.258C>A; p.A86A; 1:225888025-225888025

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.530C>A; p.A177D; 1:225887606-225887606

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - Missense

c.221G>A; p.R74H; 1:225888846-225888846

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.209G>A; p.G70E; 1:225888858-225888858

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.577C>T; p.P193S; 1:225887559-225887559

 skinmalignant_melanomaSubstitution - Missense

c.375C>T; p.V125V; 1:225887908-225887908

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.375C>T; p.V125V; 1:225887908-225887908

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.375C>T; p.V125V; 1:225887908-225887908

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.375C>T; p.V125V; 1:225887908-225887908

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.375C>T; p.V125V; 1:225887908-225887908

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.375C>T; p.V125V; 1:225887908-225887908

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.375C>T; p.V125V; 1:225887908-225887908

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.375C>T; p.V125V; 1:225887908-225887908

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.777G>A; p.E259E; 1:225887051-225887051

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.223_224GG>AA; p.G75K; 1:225888843-225888844

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.212A>G; p.D71G; 1:225888855-225888855

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.132C>G; p.D44E; 1:225888935-225888935

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - Missense

c.965A>C; p.D322A; 1:225886863-225886863

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.965A>C; p.D322A; 1:225886863-225886863

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.965A>C; p.D322A; 1:225886863-225886863

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.965A>C; p.D322A; 1:225886863-225886863

 thyroidother; neoplasmSubstitution - Missense

c.965A>C; p.D322A; 1:225886863-225886863

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.968C>T; p.S323L; 1:225886860-225886860

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.223G>A; p.G75R; 1:225888844-225888844

 skinmalignant_melanomaSubstitution - Missense

c.221G>T; p.R74L; 1:225888846-225888846

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.707A>T; p.E236V; 1:225887429-225887429

 skinmalignant_melanomaSubstitution - Missense

c.952G>A; p.A318T; 1:225886876-225886876

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.858G>A; p.P286P; 1:225886970-225886970

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1024A>T; p.S342C; 1:225886804-225886804

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.178C>A; p.Q60K; 1:225888889-225888889

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.154G>T; p.V52F; 1:225888913-225888913

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.124A>C; p.T42P; 1:225888943-225888943

 skinmalignant_melanomaSubstitution - Missense

c.881_882delTG; p.V294fs*28; 1:225886946-225886947

 endometriumcarcinoma; endometrioid_carcinomaDeletion - Frameshift

c.1045C>T; p.Q349*; 1:225886783-225886783

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Nonsense

c.1023C>A; p.V341V; 1:225886805-225886805

 ovarycarcinoma; serous_carcinomaSubstitution - coding silent

c.790T>C; p.C264R; 1:225887038-225887038

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.169G>A; p.V57M; 1:225888898-225888898

 thyroidother; neoplasmSubstitution - Missense

c.169G>A; p.V57M; 1:225888898-225888898

 thyroidother; neoplasmSubstitution - Missense

c.982G>A; p.V328I; 1:225886846-225886846

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1026C>T; p.S342S; 1:225886802-225886802

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.767C>T; p.P256L; 1:225887061-225887061

 skinmalignant_melanomaSubstitution - Missense

c.767C>T; p.P256L; 1:225887061-225887061

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.842G>C; p.W281S; 1:225886986-225886986

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.538G>A; p.V180M; 1:225887598-225887598

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.516G>C; p.E172D; 1:225887620-225887620

 cervixcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.588G>T; p.P196P; 1:225887548-225887548

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.951C>T; p.I317I; 1:225886877-225886877

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.950T>A; p.I317N; 1:225886878-225886878

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.856C>T; p.P286S; 1:225886972-225886972

 skinmalignant_melanomaSubstitution - Missense

c.678G>A; p.A226A; 1:225887458-225887458

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.685G>A; p.G229R; 1:225887451-225887451

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1077C>T; p.L359L; 1:225886751-225886751

 thyroidother; neoplasmSubstitution - coding silent

c.853C>T; p.P285S; 1:225886975-225886975

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.120G>A; p.V40V; 1:225888947-225888947

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.521G>T; p.G174V; 1:225887615-225887615

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.941G>C; p.R314P; 1:225886887-225886887

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.275T>C; p.L92S; 1:225888008-225888008

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.946T>G; p.C316G; 1:225886882-225886882

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.246C>A; p.F82L; 1:225888821-225888821

 skin; scalpcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.658C>T; p.R220C; 1:225887478-225887478

 skinmalignant_melanomaSubstitution - Missense

c.634G>A; p.A212T; 1:225887502-225887502

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.634G>A; p.A212T; 1:225887502-225887502

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.634G>A; p.A212T; 1:225887502-225887502

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.634G>A; p.A212T; 1:225887502-225887502

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.151C>T; p.L51L; 1:225888916-225888916

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.944A>G; p.Q315R; 1:225886884-225886884

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.949A>G; p.I317V; 1:225886879-225886879

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.926C>T; p.P309L; 1:225886902-225886902

 lung; middle_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.652C>G; p.L218V; 1:225887484-225887484

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.945G>T; p.Q315H; 1:225886883-225886883

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.857C>T; p.P286L; 1:225886971-225886971

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.943C>T; p.Q315*; 1:225886885-225886885

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Nonsense

c.234C>T; p.F78F; 1:225888833-225888833

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.98G>A; p.R33Q; 1:225888969-225888969

 breastcarcinomaSubstitution - Missense

c.522C>T; p.G174G; 1:225887614-225887614

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - coding silent

c.893G>A; p.R298Q; 1:225886935-225886935

 thyroidother; neoplasmSubstitution - Missense

c.384C>A; p.A128A; 1:225887899-225887899

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.267C>T; p.F89F; 1:225888016-225888016

 skinmalignant_melanomaSubstitution - coding silent

c.267C>T; p.F89F; 1:225888016-225888016

 skinmalignant_melanomaSubstitution - coding silent

c.948C>A; p.C316*; 1:225886880-225886880

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Nonsense

c.160C>T; p.P54S; 1:225888907-225888907

 skinmalignant_melanomaSubstitution - Missense

c.1027C>T; p.L343L; 1:225886801-225886801

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.1023C>T; p.V341V; 1:225886805-225886805

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

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