Entrez Gene

Basic Information
Gene ID	10481
Name	HOXB13

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
The somatic mutations from COSMIC database
c.304C>G; p.Q102E; 17:48728290-48728290	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.534G>A; p.W178*; 17:48728060-48728060	breast	carcinoma	Substitution - Nonsense
c.676G>A; p.G226R; 17:48726969-48726969	skin	malignant_melanoma	Substitution - Missense
c.457G>A; p.G153S; 17:48728137-48728137	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.761G>A; p.S254N; 17:48726884-48726884	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.605C>T; p.S202F; 17:48727040-48727040	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.435C>A; p.D145E; 17:48728159-48728159	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.846T>C; p.A282A; 17:48726799-48726799	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.233T>A; p.V78E; 17:48728361-48728361	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.649C>G; p.R217G; 17:48726996-48726996	thyroid	other; neoplasm	Substitution - Missense
c.291G>A; p.L97L; 17:48728303-48728303	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.352G>A; p.E118K; 17:48728242-48728242	skin	malignant_melanoma	Substitution - Missense
c.652A>G; p.K218E; 17:48726993-48726993	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.664C>T; p.P222S; 17:48726981-48726981	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.664C>T; p.P222S; 17:48726981-48726981	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.664C>T; p.P222S; 17:48726981-48726981	skin	malignant_melanoma	Substitution - Missense
c.227C>T; p.A76V; 17:48728367-48728367	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.220T>C; p.S74P; 17:48728374-48728374	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.194C>A; p.P65Q; 17:48728400-48728400	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.158T>C; p.L53P; 17:48728436-48728436	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.708G>T; p.A236A; 17:48726937-48726937	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.168G>T; p.S56S; 17:48728426-48728426	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.85G>A; p.A29T; 17:48728509-48728509	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.593C>T; p.A198V; 17:48728001-48728001	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.548G>T; p.C183F; 17:48728046-48728046	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.565A>G; p.N189D; 17:48728029-48728029	breast	carcinoma	Substitution - Missense
c.602-8C>T; p.?; 17:48727051-48727051	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Unknown
c.427T>A; p.Y143N; 17:48728167-48728167	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.72_73insG; p.R25fs*102; 17:48728521-48728522	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.707C>T; p.A236V; 17:48726938-48726938	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.739C>T; p.R247C; 17:48726906-48726906	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.739C>T; p.R247C; 17:48726906-48726906	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.602-4G>A; p.?; 17:48727047-48727047	pancreas	carcinoma	Unknown
c.336G>A; p.E112E; 17:48728258-48728258	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.181A>G; p.K61E; 17:48728413-48728413	pancreas	carcinoma	Substitution - Missense
c.15T>A; p.N5K; 17:48728579-48728579	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.219G>T; p.T73T; 17:48728375-48728375	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.708G>A; p.A236A; 17:48726937-48726937	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.63G>A; p.A21A; 17:48728531-48728531	skin	malignant_melanoma	Substitution - coding silent
c.256G>A; p.G86R; 17:48728338-48728338	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.640C>T; p.R214C; 17:48727005-48727005	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.646G>A; p.G216S; 17:48726999-48726999	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.154G>A; p.D52N; 17:48728440-48728440	skin	malignant_melanoma	Substitution - Missense
c.303C>A; p.A101A; 17:48728291-48728291	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.418A>G; p.M140V; 17:48728176-48728176	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.72G>A; p.G24G; 17:48728522-48728522	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.514T>G; p.W172G; 17:48728080-48728080	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.222C>T; p.S74S; 17:48728372-48728372	skin	malignant_melanoma	Substitution - coding silent
c.34G>A; p.A12T; 17:48728560-48728560	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.644G>A; p.R215H; 17:48727001-48727001	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.251G>A; p.G84E; 17:48728343-48728343	skin	malignant_melanoma	Substitution - Missense
c.772C>T; p.R258C; 17:48726873-48726873	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.290T>C; p.L97P; 17:48728304-48728304	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.210C>T; p.P70P; 17:48728384-48728384	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.556G>A; p.G186R; 17:48728038-48728038	skin	malignant_melanoma	Substitution - Missense
c.585G>A; p.W195*; 17:48728009-48728009	skin	malignant_melanoma	Substitution - Nonsense
c.641G>A; p.R214H; 17:48727004-48727004	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.641G>A; p.R214H; 17:48727004-48727004	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.557G>A; p.G186E; 17:48728037-48728037	skin	malignant_melanoma	Substitution - Missense
c.131C>A; p.P44H; 17:48728463-48728463	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.666G>A; p.P222P; 17:48726979-48726979	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.578C>G; p.P193R; 17:48728016-48728016	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.628G>A; p.A210T; 17:48727017-48727017	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.665C>T; p.P222L; 17:48726980-48726980	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.665C>T; p.P222L; 17:48726980-48726980	breast	carcinoma	Substitution - Missense
c.832G>T; p.V278L; 17:48726813-48726813	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.654G>C; p.K218N; 17:48726991-48726991	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.218C>T; p.T73M; 17:48728376-48728376	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.767C>G; p.S256W; 17:48726878-48726878	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.658C>T; p.R220C; 17:48726987-48726987	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.271C>A; p.R91R; 17:48728323-48728323	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.654G>A; p.K218K; 17:48726991-48726991	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent

The somatic mutations from COSMIC database