Entrez Gene

Basic Information
Gene ID	10468
Name	FST

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
The somatic mutations from COSMIC database
c.922_923insT; p.E309fs*22; 5:53485197-53485198	breast	carcinoma	Insertion - Frameshift
c.621T>C; p.C207C; 5:53484193-53484193	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.979G>T; p.E327*; 5:53485977-53485977	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.498G>T; p.K166N; 5:53484070-53484070	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.498G>T; p.K166N; 5:53484070-53484070	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.343C>T; p.R115C; 5:53483569-53483569	skin	malignant_melanoma	Substitution - Missense
c.580C>T; p.R194W; 5:53484152-53484152	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.157G>A; p.E53K; 5:53482951-53482951	skin	malignant_melanoma	Substitution - Missense
c.438A>G; p.L146L; 5:53483664-53483664	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.199G>C; p.E67Q; 5:53482993-53482993	urinary_tract; bladder	carcinoma	Substitution - Missense
c.976G>T; p.E326*; 5:53485974-53485974	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.7C>T; p.R3C; 5:53480798-53480798	oesophagus	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.670A>G; p.T224A; 5:53484242-53484242	adrenal_gland; adrenal_gland	adrenal_cortical_carcinoma; functioning	Substitution - Missense
c.100C>T; p.L34F; 5:53482894-53482894	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.225C>A; p.L75L; 5:53483019-53483019	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.638C>A; p.T213N; 5:53484210-53484210	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.126C>A; p.C42*; 5:53482920-53482920	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Nonsense
c.411A>G; p.K137K; 5:53483637-53483637	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.228C>T; p.F76F; 5:53483022-53483022	breast	carcinoma	Substitution - coding silent
c.695G>A; p.G232E; 5:53484267-53484267	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.798G>T; p.R266R; 5:53485073-53485073	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.722-4C>T; p.?; 5:53484993-53484993	pancreas	carcinoma	Unknown
c.495A>C; p.K165N; 5:53483721-53483721	breast	carcinoma	Substitution - Missense
c.500C>T; p.T167I; 5:53484072-53484072	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.754G>T; p.G252C; 5:53485029-53485029	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.573C>T; p.T191T; 5:53484145-53484145	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1016C>G; p.S339C; 5:53486014-53486014	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.541G>T; p.V181L; 5:53484113-53484113	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.775G>A; p.D259N; 5:53485050-53485050	skin; mucosal	malignant_melanoma	Substitution - Missense
c.289A>G; p.N97D; 5:53483515-53483515	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.838G>C; p.D280H; 5:53485113-53485113	urinary_tract; bladder	carcinoma	Substitution - Missense
c.424G>A; p.E142K; 5:53483650-53483650	breast	carcinoma; HER-positive_carcinoma	Substitution - Missense
c.168C>A; p.C56*; 5:53482962-53482962	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.497-1G>C; p.?; 5:53484068-53484068	skin; head_neck	carcinoma; squamous_cell_carcinoma	Unknown
c.960G>T; p.S320S; 5:53485958-53485958	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.470A>G; p.E157G; 5:53483696-53483696	breast	carcinoma	Substitution - Missense
c.703T>C; p.Y235H; 5:53484275-53484275	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.771A>T; p.L257F; 5:53485046-53485046	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.371A>T; p.N124I; 5:53483597-53483597	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.206A>G; p.D69G; 5:53483000-53483000	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.320G>A; p.R107Q; 5:53483546-53483546	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.145G>A; p.E49K; 5:53482939-53482939	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.86C>G; p.A29G; 5:53482880-53482880	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.396C>T; p.C132C; 5:53483622-53483622	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.759_760insA; p.C256fs*16; 5:53485034-53485035	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.309G>A; p.G103G; 5:53483535-53483535	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.914G>A; p.G305D; 5:53485189-53485189	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.52C>T; p.L18F; 5:53480843-53480843	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.713A>T; p.K238M; 5:53484285-53484285	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.836C>T; p.S279L; 5:53485111-53485111	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.136T>C; p.Y46H; 5:53482930-53482930	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.42G>C; p.L14L; 5:53480833-53480833	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.976G>A; p.E326K; 5:53485974-53485974	skin	malignant_melanoma	Substitution - Missense
c.191C>T; p.S64L; 5:53482985-53482985	biliary_tract; gallbladder	carcinoma; adenocarcinoma	Substitution - Missense
c.397G>A; p.G133R; 5:53483623-53483623	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.399G>A; p.G133G; 5:53483625-53483625	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.104G>T; p.R35L; 5:53482898-53482898	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.295G>A; p.D99N; 5:53483521-53483521	skin	malignant_melanoma	Substitution - Missense
c.446G>T; p.R149I; 5:53483672-53483672	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.414C>A; p.T138T; 5:53483640-53483640	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.414C>A; p.T138T; 5:53483640-53483640	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.871T>C; p.Y291H; 5:53485146-53485146	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.176G>A; p.G59D; 5:53482970-53482970	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1010C>T; p.P337L; 5:53486008-53486008	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.959C>T; p.S320L; 5:53485957-53485957	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.959C>T; p.S320L; 5:53485957-53485957	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.959C>T; p.S320L; 5:53485957-53485957	skin	malignant_melanoma	Substitution - Missense
c.959C>T; p.S320L; 5:53485957-53485957	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.354C>T; p.C118C; 5:53483580-53483580	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.540G>T; p.V180V; 5:53484112-53484112	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.814G>A; p.E272K; 5:53485089-53485089	stomach	carcinoma; adenocarcinoma	Substitution - Missense

The somatic mutations from COSMIC database