Entrez Gene

Basic Information
Gene ID	10252
Name	SPRY1

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
The somatic mutations from COSMIC database
c.241A>G; p.I81V; 4:123401832-123401832	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.675C>T; p.V225V; 4:123402266-123402266	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.764C>G; p.S255C; 4:123402355-123402355	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.677A>G; p.K226R; 4:123402268-123402268	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.887G>A; p.R296K; 4:123402478-123402478	skin	malignant_melanoma	Substitution - Missense
c.617G>A; p.R206Q; 4:123402208-123402208	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.408A>G; p.L136L; 4:123401999-123401999	breast	carcinoma	Substitution - coding silent
c.874C>T; p.R292C; 4:123402465-123402465	skin	malignant_melanoma	Substitution - Missense
c.874C>T; p.R292C; 4:123402465-123402465	breast	carcinoma	Substitution - Missense
c.578C>A; p.T193N; 4:123402169-123402169	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.137C>A; p.A46D; 4:123401728-123401728	urinary_tract; bladder	carcinoma	Substitution - Missense
c.291G>T; p.L97L; 4:123401882-123401882	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.662G>T; p.C221F; 4:123402253-123402253	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.510G>C; p.L170F; 4:123402101-123402101	breast	carcinoma	Substitution - Missense
c.813C>T; p.L271L; 4:123402404-123402404	skin	malignant_melanoma	Substitution - coding silent
c.537C>T; p.F179F; 4:123402128-123402128	skin	malignant_melanoma	Substitution - coding silent
c.948T>C; p.G316G; 4:123402539-123402539	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.173C>T; p.S58L; 4:123401764-123401764	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.197G>A; p.R66Q; 4:123401788-123401788	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.395A>C; p.E132A; 4:123401986-123401986	ovary	other; neoplasm	Substitution - Missense
c.4G>A; p.D2N; 4:123401595-123401595	skin	malignant_melanoma	Substitution - Missense
c.663C>T; p.C221C; 4:123402254-123402254	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.605T>C; p.L202S; 4:123402196-123402196	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.663C>T; p.C221C; 4:123402254-123402254	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.193C>T; p.P65S; 4:123401784-123401784	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.944A>G; p.Q315R; 4:123402535-123402535	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.944A>G; p.Q315R; 4:123402535-123402535	urinary_tract; bladder	carcinoma	Substitution - Missense
c.235G>A; p.E79K; 4:123401826-123401826	skin	malignant_melanoma	Substitution - Missense
c.823C>T; p.P275S; 4:123402414-123402414	skin	malignant_melanoma	Substitution - Missense
c.320G>T; p.R107M; 4:123401911-123401911	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.48C>G; p.I16M; 4:123401639-123401639	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.762C>A; p.C254*; 4:123402353-123402353	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.463C>T; p.R155W; 4:123402054-123402054	skin	malignant_melanoma	Substitution - Missense
c.287A>C; p.H96P; 4:123401878-123401878	breast	carcinoma	Substitution - Missense
c.324C>T; p.G108G; 4:123401915-123401915	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.324C>T; p.G108G; 4:123401915-123401915	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.82G>A; p.D28N; 4:123401673-123401673	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.733C>T; p.P245S; 4:123402324-123402324	skin	malignant_melanoma	Substitution - Missense
c.287A>G; p.H96R; 4:123401878-123401878	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.249T>C; p.I83I; 4:123401840-123401840	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.5A>G; p.D2G; 4:123401596-123401596	breast	carcinoma	Substitution - Missense
c.604T>G; p.L202V; 4:123402195-123402195	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.662G>A; p.C221Y; 4:123402253-123402253	skin	malignant_melanoma	Substitution - Missense
c.12A>C; p.Q4H; 4:123401603-123401603	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.571G>T; p.E191*; 4:123402162-123402162	breast	carcinoma	Substitution - Nonsense
c.887G>T; p.R296I; 4:123402478-123402478	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.776G>A; p.C259Y; 4:123402367-123402367	skin; face	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.593T>C; p.L198P; 4:123402184-123402184	breast	carcinoma	Substitution - Missense
c.577A>G; p.T193A; 4:123402168-123402168	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.935C>T; p.S312F; 4:123402526-123402526	skin	malignant_melanoma	Substitution - Missense
c.935C>T; p.S312F; 4:123402526-123402526	skin	malignant_melanoma	Substitution - Missense
c.35C>T; p.S12L; 4:123401626-123401626	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.762C>T; p.C254C; 4:123402353-123402353	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.266A>G; p.Y89C; 4:123401857-123401857	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.956C>G; p.S319*; 4:123402547-123402547	breast	carcinoma	Substitution - Nonsense
c.275G>A; p.R92K; 4:123401866-123401866	NS	NS	Substitution - Missense
c.678G>T; p.K226N; 4:123402269-123402269	stomach	carcinoma; adenocarcinoma	Substitution - Missense

The somatic mutations from COSMIC database