Entrez Gene

Basic Information
Gene ID	10131
Name	TRAP1

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
The somatic mutations from COSMIC database
c.1565C>G; p.T522R; 16:3664278-3664278	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.951C>G; p.Y317*; 16:3674432-3674432	central_nervous_system; temporal_lobe	glioma; astrocytoma_Grade_IV	Substitution - Nonsense
c.1527G>A; p.E509E; 16:3664316-3664316	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1666G>A; p.V556M; 16:3663466-3663466	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.362G>T; p.S121I; 16:3686105-3686105	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1834G>A; p.V612M; 16:3662093-3662093	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.786G>T; p.K262N; 16:3676064-3676064	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.546C>A; p.A182A; 16:3677656-3677656	skin	malignant_melanoma	Substitution - coding silent
c.957G>T; p.A319A; 16:3674426-3674426	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1301C>T; p.A434V; 16:3666053-3666053	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.407A>T; p.Q136L; 16:3686060-3686060	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1049C>T; p.P350L; 16:3672816-3672816	skin	malignant_melanoma	Substitution - Missense
c.1747A>G; p.M583V; 16:3662929-3662929	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1190_1191CC>TT; p.P397L; 16:3671766-3671767	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1655C>T; p.T552M; 16:3663477-3663477	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1184A>G; p.D395G; 16:3671773-3671773	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.787G>A; p.E263K; 16:3676063-3676063	skin	malignant_melanoma	Substitution - Missense
c.1415C>T; p.S472F; 16:3664428-3664428	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.543+6C>T; p.?; 16:3679713-3679713	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Unknown
c.1805G>A; p.R602Q; 16:3662122-3662122	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.1636A>C; p.K546Q; 16:3663496-3663496	pancreas	carcinoma	Substitution - Missense
c.1981G>C; p.E661Q; 16:3658825-3658825	central_nervous_system; medulla	primitive_neuroectodermal_tumour-medulloblastoma; classic	Substitution - Missense
c.383G>A; p.R128H; 16:3686084-3686084	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1103G>A; p.R368H; 16:3672762-3672762	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1981G>A; p.E661K; 16:3658825-3658825	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.178A>G; p.S60G; 16:3690896-3690896	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.838T>C; p.F280L; 16:3675374-3675374	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.704+3G>C; p.?; 16:3677495-3677495	skin; head_neck	carcinoma; squamous_cell_carcinoma	Unknown
c.1166-1G>A; p.?; 16:3671792-3671792	skin; arm	malignant_melanoma	Unknown
c.1260G>C; p.Q420H; 16:3666094-3666094	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1430C>T; p.S477F; 16:3664413-3664413	skin	malignant_melanoma	Substitution - Missense
c.1684_1686delGAG; p.E562delE; 16:3663446-3663448	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Deletion - In frame
c.1221G>C; p.E407D; 16:3671736-3671736	breast	carcinoma	Substitution - Missense
c.5C>A; p.A2E; 16:3717504-3717504	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2048T>C; p.V683A; 16:3658196-3658196	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.904G>A; p.D302N; 16:3674479-3674479	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1205G>A; p.R402Q; 16:3671752-3671752	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1205G>A; p.R402Q; 16:3671752-3671752	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1530C>T; p.H510H; 16:3664313-3664313	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.841G>A; p.V281I; 16:3675371-3675371	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.385C>T; p.H129Y; 16:3686082-3686082	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.825G>A; p.T275T; 16:3675387-3675387	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.264T>C; p.H88H; 16:3689121-3689121	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1946C>T; p.A649V; 16:3658860-3658860	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1406G>A; p.R469H; 16:3664437-3664437	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - Missense
c.1018C>T; p.R340C; 16:3674365-3674365	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1018C>T; p.R340C; 16:3674365-3674365	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1185C>G; p.D395E; 16:3671772-3671772	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1503C>T; p.C501C; 16:3664340-3664340	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.415C>T; p.P139S; 16:3686052-3686052	skin; acral	malignant_melanoma	Substitution - Missense
c.672G>A; p.P224P; 16:3677530-3677530	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.270C>A; p.F90L; 16:3689115-3689115	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1711G>A; p.A571T; 16:3662965-3662965	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1903G>A; p.A635T; 16:3662024-3662024	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.13C>A; p.L5M; 16:3717496-3717496	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1953C>T; p.I651I; 16:3658853-3658853	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.840C>T; p.F280F; 16:3675372-3675372	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1635G>A; p.K545K; 16:3663497-3663497	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1141C>T; p.P381S; 16:3672724-3672724	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.382C>T; p.R128C; 16:3686085-3686085	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.1021A>T; p.S341C; 16:3674362-3674362	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.1000G>A; p.D334N; 16:3674383-3674383	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1224C>T; p.S408S; 16:3671733-3671733	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1515T>C; p.R505R; 16:3664328-3664328	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1003G>A; p.A335T; 16:3674380-3674380	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.646G>T; p.E216*; 16:3677556-3677556	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.760A>G; p.I254V; 16:3676090-3676090	ovary	carcinoma	Substitution - Missense
c.1423C>T; p.L475L; 16:3664420-3664420	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	Substitution - coding silent
c.998C>T; p.T333M; 16:3674385-3674385	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.233_234delCA; p.T78fs*11; 16:3690840-3690841	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1813A>C; p.T605P; 16:3662114-3662114	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1813A>C; p.T605P; 16:3662114-3662114	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1813A>C; p.T605P; 16:3662114-3662114	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1813A>C; p.T605P; 16:3662114-3662114	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.107C>T; p.P36L; 16:3690967-3690967	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1813A>C; p.T605P; 16:3662114-3662114	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1813A>C; p.T605P; 16:3662114-3662114	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1813A>C; p.T605P; 16:3662114-3662114	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1669G>A; p.D557N; 16:3663463-3663463	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.2019C>T; p.Y673Y; 16:3658225-3658225	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1710C>T; p.A570A; 16:3662966-3662966	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - coding silent
c.778G>A; p.D260N; 16:3676072-3676072	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.778G>A; p.D260N; 16:3676072-3676072	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.852C>T; p.P284P; 16:3675360-3675360	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.109C>T; p.R37W; 16:3690965-3690965	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.331-10A>G; p.?; 16:3686146-3686146	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Unknown
c.155G>T; p.S52I; 16:3690919-3690919	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.775T>C; p.S259P; 16:3676075-3676075	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1631A>C; p.K544T; 16:3663501-3663501	skin	malignant_melanoma	Substitution - Missense
c.1708+3C>T; p.?; 16:3663421-3663421	liver	carcinoma	Unknown
c.1865T>A; p.L622Q; 16:3662062-3662062	bone; pelvis	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.1708+3C>T; p.?; 16:3663421-3663421	liver	carcinoma	Unknown
c.1798A>C; p.T600P; 16:3662129-3662129	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1798A>C; p.T600P; 16:3662129-3662129	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1798A>C; p.T600P; 16:3662129-3662129	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1798A>C; p.T600P; 16:3662129-3662129	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1798A>C; p.T600P; 16:3662129-3662129	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1798A>C; p.T600P; 16:3662129-3662129	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1657G>T; p.D553Y; 16:3663475-3663475	thyroid	other; neoplasm	Substitution - Missense
c.526G>T; p.A176S; 16:3679736-3679736	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.1927G>A; p.E643K; 16:3662000-3662000	skin	malignant_melanoma	Substitution - Missense
c.1165+4C>T; p.?; 16:3672696-3672696	oesophagus; lower_third	carcinoma; adenocarcinoma	Unknown
c.210C>A; p.P70P; 16:3690864-3690864	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1280T>A; p.I427N; 16:3666074-3666074	cervix	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1016T>A; p.I339N; 16:3674367-3674367	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1636_1638delAAG; p.K546delK; 16:3663494-3663496	endometrium	carcinoma; endometrioid_carcinoma	Deletion - In frame
c.1431C>T; p.S477S; 16:3664412-3664412	breast	carcinoma	Substitution - coding silent
c.1777C>T; p.R593C; 16:3662899-3662899	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1205G>T; p.R402L; 16:3671752-3671752	adrenal_gland; adrenal_gland	adrenal_cortical_carcinoma; functioning	Substitution - Missense
c.164C>T; p.A55V; 16:3690910-3690910	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1483C>T; p.R495C; 16:3664360-3664360	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1200C>T; p.L400L; 16:3671757-3671757	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1471C>T; p.R491W; 16:3664372-3664372	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1972C>T; p.R658C; 16:3658834-3658834	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.533C>T; p.S178L; 16:3679729-3679729	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.509C>G; p.S170C; 16:3679753-3679753	breast	carcinoma	Substitution - Missense
c.189C>T; p.T63T; 16:3690885-3690885	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.378A>C; p.K126N; 16:3686089-3686089	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.340C>T; p.R114W; 16:3686127-3686127	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.639_640delCA; p.D213fs*27; 16:3677562-3677563	central_nervous_system; brainstem	glioma; astrocytoma_Grade_II	Deletion - Frameshift
c.1204C>T; p.R402W; 16:3671753-3671753	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.193G>A; p.E65K; 16:3690881-3690881	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.799G>A; p.E267K; 16:3676051-3676051	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense

The somatic mutations from COSMIC database