| General information | Literature | Expression | lncRNA |Regulation | Mutation | Homolog | Interaction |
Basic Information | From Entrez database: 1977 |
|---|---|
Gene ID | 1977 |
Name | EIF4E |
Synonym | AUTS19|CBP|EIF4E1|EIF4EL1|EIF4F;eukaryotic translation initiation factor 4E;EIF4E;eukaryotic translation initiation factor 4E |
Definition | eIF-4E|eIF-4F 25 kDa subunit|eukaryotic translation initiation factor 4E-like 1|mRNA cap-binding protein |
Position | 4q23 |
Gene Type | protein-coding |
Pathways and Diseases | From KEGG database |
Pathway | Signaling by Insulin receptor;Reactome;REACT:498 |
Pathway | Transport of Mature Transcript to Cytoplasm;PID Reactome;500657 |
Pathway | Transport of Mature mRNA derived from an Intron-Containing Transcript;PID Reactome;500928 |
Pathway | Transport of Mature mRNA Derived from an Intronless Transcript;PID Reactome;500862 |
Pathway | Release of eIF4E;PID Reactome;500965 |
Pathway | Metabolism of RNA;Reactome;REACT:21257 |
Pathway | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met);PID Curated;200032 |
Pathway | 3' -UTR-mediated translational regulation;Reactome;REACT:1762 |
Pathway | eukaryotic protein translation;PID BioCarta;100177 |
Pathway | Transport of the SLBP Dependant Mature mRNA;PID Reactome;500899 |
Pathway | Signaling mediated by p38-alpha and p38-beta;PID Curated;200154 |
Pathway | Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S;PID Reactome;500880 |
Pathway | Validated targets of C-MYC transcriptional activation;PID Curated;200045 |
Pathway | Gene Expression;Reactome;REACT:71 |
Pathway | GTP hydrolysis and joining of the 60S ribosomal subunit;PID Reactome;500970 |
Pathway | Insulin signaling pathway;KEGG PATHWAY;hsa04910 |
Pathway | internal ribosome entry pathway;PID BioCarta;100120 |
Pathway | Transport of Mature mRNAs Derived from Intronless Transcripts;PID Reactome;500658 |
Pathway | Metabolism of proteins;Reactome;REACT:17015 |
Pathway | mTOR signaling pathway;KEGG PATHWAY;hsa04150 |
Pathway | skeletal muscle hypertrophy is regulated via akt-mtor pathway;PID BioCarta;100137 |
Pathway | mTOR signaling pathway;PID Curated;200080 |
Pathway | Cap-dependent Translation Initiation;PID Reactome;500901 |
Pathway | Deadenylation of mRNA;PID Reactome;500855 |
Pathway | regulation of eif-4e and p70s6 kinase;PID BioCarta;100178 |
Pathway | mRNA Processing;Reactome;REACT:1675 |
Pathway | mtor signaling pathway;PID BioCarta;100101 |
Pathway | Transport of the SLBP independent Mature mRNA;PID Reactome;500879 |
Disease | Leukoencephalopathy;FunDO |
Disease | Cancer;FunDO |
Disease | Diabetes mellitus;FunDO |
Disease | Adenovirus infection;FunDO |
External Links | |
Links to Entrez Gene | 1977 |
Links to all GeneRIF Items | 1977 |
Sequence Information | |
Nucleotide Sequence | >1977 : length: 4842 GCACAGGCAGCCTGCATACACTCCTTTTCCTGGTGTCAACATTATTTAAAAGCATGGGAA ATAGTAATGAGACAGTGTCTTCTTCATTAGAACCTTAGGAGTCTACTAGATTTCTTCATC TCTATTTGTTGTTATTAGTAGCCAAACTGTGCAAAAAACACGGTCTTGAGAAATGACAGC ACAGTATCTTAGAGGGAAAGGAAATGTAGGATGCCAGTGTGGGGACAAATTTCTGATTGC CAGTGATTGTTGTGAGCATAACAATAATTTCATGAACATTAAAGCCTCTATTGAGGGCAG CTGCAGTTGTAAAGGAAAAAAAATGGTCCTGAACATTTAAAACTACACTGGTGTACATCA TAATCAAACAAAGTAAACAGAAAAAAATTTAAACTTTGCTAAAAAAAAAAAGCAGAAGCA CTTGATCTTTAGGAAGGCACGCAGTTGCTTATTATGAATCATTTCTAGAGTCCGATGCAT TTTCAAAGCCGGTTACAGTCATTACGAAGCACACCCTTGTGAGGTAAGTGTATCATCACC TTTGGTTCATAAATAAAAAAGCTGAGACGCCGAGCGATTAAGTCACTCGCCTAAGGAGAA TGAGTCAACGTCAAGAGTCATAGTTGACCCGGCCTAAAGACTCCAGACCATCAGTCCAGG GCTTAGTCAGCGGGGCCCGGAGTGGCTTCCCTGGCTGGCATCTGGACTTAGGCTATTTCC GTGCACGTAAAAGCGGAATATTGGAACGGTTGCACAGAACTTCCAAATAATTTTTACCGC CACGCAAGATTTAGCCCTGAGGTCTTAATCTCAGGATTTGGGACAGTAAAAGCTGTCGTC CCTCCCCCTCGTCCAGCCGGTGGCAAGCGGGTACTGCGGGCGGTTCCGTCCGTCCCCTTT CGCAGAAATGGCAACGAATGACCACCAGCATTAGCTGAGCCAGGGGACGTGGGAGGGTTG ATTGCCTAAACGACTCTGCATCGCCGCCTCTTTTTGAAACTAAGAGAAAATGGTGGGAGA TCAAAAGAAAACTAAATAAACACACAGGCAACTTGTCCTGGGACCTCAACTAAGCAAATG AAGCCTTATTGTGTGTGCTGAGCCTGCAGTTCCCAACCTTCCGGGGAAGATGGGAGGACA GGGCGACAAAGGGCACAGTAGGCTTGCCTGGCAGTAAGTGTGACCGCAGCTATCCAGGCG GAAGAGCAGAGGACTGAAACCACCCTCCAGCAAGCGAGTGTCCGCCGCGTTGAGAACCGC GCACCCTACCCATCGGCCACGTGACCAGTCCTTTTTAAAAAAAATTTCTTTACCTTAAAA AAAAAAAAAAAAAAAAGGTGGGGGAGAGACTCCACTTCCCAGAAGCCTCTCGTTACTCAC GCAGCCGCAGTCTTGCGCAGGTGCCGCCAGGGCCAAACGGACATATCCGTCACGTGGCCA GAAGCTGGCCAATCCGGTTTGAATCTCATTTTTTTCCTCTTACCCCCCCTTCTGGAGCGG TTGTGCGATCAGATCGATCTAAGATGGCGACTGTCGAACCGGAAACCACCCCTACTCCTA ATCCCCCGACTACAGAAGAGGAGAAAACGGAATCTAATCAGGAGGTTGCTAACCCAGAAC ACTATATTAAACATCCCCTACAGAACAGATGGGCACTCTGGTTTTTTAAAAATGATAAAA GCAAAACTTGGCAAGCAAACCTGCGGCTGATCTCCAAGTTTGATACTGTTGAAGACTTTT GGGCTCTGTACAACCATATCCAGTTGTCTAGTAATTTAATGCCTGGCTGTGACTACTCAC TTTTTAAGGATGGTATTGAGCCTATGTGGGAAGATGAGAAAAACAAACGGGGAGGACGAT GGCTAATTACATTGAACAAACAGCAGAGACGAAGTGACCTCGATCGCTTTTGGCTAGAGA CAAGATGGGATCTTGCTATGTTGCCCAGGTTGGTCTCAAACTTCTGGCCTCAAGTGATCC TCCCACTTCAGCCTCCCAAAGTGCTGGAATTACAGCTTCTGTGCCTTATTGGAGAATCTT TTGATGACTACAGTGATGATGTATGTGGCGCTGTTGTTAATGTTAGAGCTAAAGGTGATA AGATAGCAATATGGACTACTGAATGTGAAAACAGAGAAGCTGTTACACATATAGGGAGGG TATACAAGGAAAGGTTAGGACTTCCTCCAAAGATAGTGATTGGTTATCAGTCCCACGCAG ACACAGCTACTAAGAGCGGCTCCACCACTAAAAATAGGTTTGTTGTTTAAGAAGACACCT TCTGAGTATTCTCATAGGAGACTGCGTCAAGCAATCGAGATTTGGGAGCTGAACCAAAGC CTCTTCAAAAAGCAGAGTGGACTGCATTTAAATTTGATTTCCATCTTAATGTTACTCAGA TATAAGAGAAGTCTCATTCGCCTTTGTCTTGTACTTCTGTGTTCATTTTTTTTTTTTTTT TTGGCTAGAGTTTCCACTATCCCAATCAAAGAATTACAGTACACATCCCCAGAATCCATA AATGTGTTCCTGGCCCACTCTGTAATAGTTCAGTAGAATTACCATTAATTACATACAGAT TTTACCTATCCACAATAGTCAGAAAACAACTTGGCATTTCTATACTTTACAGGAAAAAAA ATTCTGTTGTTCCATTTTATGCAGAAGCATATTTTGCTGGTTTGAAAGATTATGATGCAT ACAGTTTTCTAGCAATTTTCTTTGTTTCTTTTTACAGCATTGTCTTTGCTGTACTCTTGC TGATGGCTGCTAGATTTTAATTTATTTGTTTCCCTACTTGATAATATTAGTGATTCTGAT TTCAGTTTTTCATTTGTTTTGCTTTTGTTTTTTTCCTCATGTAACATTGGTGAAGGATCC AGGAATATGACACAAAGGTGGAATAAACATTAATTTTGTGCATTCTTTGGTAATTTTTTT TGTTTTTTGTAACTACAAAGCTTTGCTACAAATTTATGCATTTCATTCAAATCAGTGATC TATGTTTGTGTGATTTCCTAAACATAATTGTGGATTATAAAAAATGTAACATCATAATTA CATTCCTAACTAGAATTAGTATGTCTGTTTTTGTATCTTTATGCTGTATTTTAACACTTT GTATTACTTAGGTTATTTTGCTTTGGTTAAAAATGGCTCAAGTAGAAAAGCAGTCCCATT CATATTAAGACAGTGTACAAAACTGTAAATAAAATGTGTACAGTGAATTGTCTTTTAGAC AACTAGATTTGTCCTTTTATTTCTCCATCTTTATAGAAGGAATTTGTACTTCTTATTGCA AGGCAGTCTCTATATTATGTCTTCTTTTGTGGTGTCTTCCATGTGAACAGCATAAGTTTG GAGCACTAGTTTGATTATTATGTTTATTACAATTTTTAATAAATTGAATAGGTAGTATCA TATATATGGAATTAAATTGATGTGGCTATCTTTGTTTTTTTATAAAGTAAGGCACAGTCA TTCAGTCTTAGGTAAATAATGTACTCTCTTAATATGTTAATACTCATGAGAATTGGGATC TGATGCATCACCATTTGATTGGTAGCAACAGTGGTTGTAAAACTTGGTTGCTGAATTGAG TTGTTTCTATGTTAAGTGTCAAAATGATAGTGTAGGGAAAGTACAGGTGGTGGGGACATA TGCATTAAGAATCTTGTTAGTGTTGCAATCTAAATAGAATGGAATAAACAGGTGTTAAGA CATATTTATAGTGGTAAATTGTTGTAGTATGGTATTCTGTAAACTTGAAAACTTGATCTA CTCTTTGTAGGTATCATTTGAAAGCAAACTTGAAAATGTTTTGTACATAGTACATACTTG TATAGTCCTGTGAGATGAAGTATGGCTATCAGACCAAAGGATAAGCCAAACTGTAGGTAG CAGAATGGAAATTATTATTTTGAGAGGAAAATTTGTCTTTGAATGGTGATTATGACTTAA TCATTTTAAAACTGATAAACTTGACAAAAACCCTGTATGAAATAAACATGAAATTAATAG CACTGATTTCATTGTAAAATTTTAAAGCAGTTTAAAGGGTACCACAGGTTATCACAGTAC TCTCAATGCCACAAACACCTCTTGTTCAGTATTCTAGAAATACTGAATCAGAATTCTGTG TTTATTATAATCTCAGCATACTGTACATAATATCTGCTAGTTAAACTTGGGTAATTGGTT AAGGTGACTTACTGTCTATGTCAATATGTATAGTTTTGAGTACTTCAAGAGTTTACTTAA AAGTGATGATGTTACTGGTATGTTGGCAGTGGGTGGGACTGAAGTAGTGTATCTATTATA AATTGATCTATTTTCTTAATTCTAAGATGAAGTCCAATTTTAAGCATCAGCTTTTAGGTG CAAAGGAGGAATTAACACATTAAATGTATACAGTTCTAAATTTTTGAAATAACTGATGTG TAGCATTTGATTATTGGTATTACCATTTTAGAATCATGATGTTATTTTAAACCTTTTTCC TGGGGACAAGAAAGGATAATAAATTACGCTGAATCACTTTTGGCAGTTGCCACTTAAATA GTACAGTGACTTGCAACTTTTATAACTTTATCAGCATCTTCTCTAAATACAAAATTAGGC TATATGTTATTTTCCAACTTACTGTTTTCTCTCTGTTTAGCAGGATATTATAAATAGATT AAATAGATATATTTTCTTTTTTTTTTTTTTTTTTTGAGACGGAGTCTCGCTTTGTCTCCC AGGCTGGAGTGCAGTGGCGTGATCTCCCAGTAGCTGGGACTACAAGCACCTGCCACCATG CCCGGCTAATTTTTTTTGTATTTTTAGTAGAGACGGGGTTTC |