Entrez Gene

Basic Information
Gene ID	875
Name	CBS
Synonymous	cystathionine-beta-synthase;CBS;cystathionine-beta-synthase
Definition	beta-thionase\|cystathionine beta-synthase\|methylcysteine synthase\|serine sulfhydrase
Position	21q22.3
Gene Type	protein-coding
Gene Regulation:	Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database

Regulation From TransFac database
Transcription Factors [Top]
cystathionine beta-synthase isoform-1(h) + Ubc9(h) <==> cystathionine beta-synthase isoform-1(h):Ubc9(h) (binding)
cystathionine beta-synthase isoform-1(h) + PIAS1(h) <==> cystathionine beta-synthase isoform-1(h):PIAS1(h) (binding)
cystathionine beta-synthase isoform-1(h) + PIAS3(h) <==> cystathionine beta-synthase isoform-1(h):PIAS3(h) (binding)
cystathionine beta-synthase isoform-1(h) + RanBPM(h) <==> cystathionine beta-synthase isoform-1(h):RanBPM(h) (binding)
cystathionine beta-synthase isoform-1(h) + Pc2(h) <==> cystathionine beta-synthase isoform-1(h):Pc2(h) (binding)
cystathionine beta-synthase isoform-1(h) + sumo1(h) --Aos1(h):SAE2(h),PIAS1(m.s.),Ubc9(h)--> cystathionine beta-synthase isoform-1(h){sumoK211} (sumoylation)
CBS(h) --> cystathionine beta-synthase isoform-1(h) (expression).
2 cystathionine beta-synthase(h) <==> (cystathionine beta-synthase(h))2 (binding)
cystathionine beta-synthase(h) + FXR2(h) <==> cystathionine beta-synthase(h):FXR2(h) (binding)
cystathionine beta-synthase(h) + My012(h) <==> cystathionine beta-synthase(h):My012(h) (binding)
cystathionine beta-synthase(h) + DMC1(h) <==> cystathionine beta-synthase(h):DMC1(h) (binding)
CBS(h) --> cystathionine beta-synthase(h) (expression).
CBS(h) --> cystathionine beta-synthase isoform-2(h) (expression).

Location (AA)	PTM type	Literature	Database
Post Transcriptional Modification [Top]
211	Glycyl lysine isopeptide (Lys-Gly)(interchain with G-Cter in SUMO).		Swiss-Prot 53.0

Transcription Factors [Top]