Cell senescence gene database Home
Cell senescence database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

8697

Name

CDC23

Synonymous

cell division cycle 23;CDC23;cell division cycle 23

Definition

anaphase promoting complex subunit 8|anaphase-promoting complex subunit 8|cell division cycle 23 homolog|cell division cycle protein 23 homolog|cyclosome subunit 8

Position

5q31

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors   [Top]

Regulation From TransFac database

Cdc23(h) + ATP --cyclinB1(h):Cdk1(h):Cks1(h)--> Cdc23(h){pT556} + ADP (phosphorylation)
Cdc23(h) + ATP --cyclinB1(h):Cdk1(h):Cks1(h)--> Cdc23(h){pT559} + ADP (phosphorylation)
Cdc23(h) + ATP --cyclinB1(h):Cdk1(h):Cks1(h)--> Cdc23(h){pT576} + ADP (phosphorylation)
Emi1(h) + Cdc23(h) <==> Emi1(h):Cdc23(h) (binding)
APC1(h) + APC11(h) + APC2(h) + APC4(h) + APC5(h) + APC7(h) + Cdc16(h) + Cdc23(h) + Emi1(h) + Fzr1(h) <==> APC1(h):APC2(h):APC4(h):APC5(h):Cdc16(h):APC7(h):Cdc23(h):APC11(h):Fzr1(h):Emi1(h) (binding)
Cdc23(h) + Emi1(h) <==> Cdc23(h):Emi1(h) (binding)
Cdc27(h) + Cdc23(h) <==> Cdc27(h):Cdc23(h) (binding)
Cdc23(h) + rbpms(h) <==> Cdc23(h):rbpms(h) (binding)
Cdc23(h) + Rad54B(h) <==> Cdc23(h):Rad54B(h) (binding)
Cdc23(h) + Tilz2(h) <==> Cdc23(h):Tilz2(h) (binding)
CDC23(h) --> Cdc23(h) (expression).
CDC23(h) --> Cdc23(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

267Phosphotyrosine.Swiss-Prot 53.0
556Phosphothreonine.Swiss-Prot 53.0
559Phosphothreonine.Swiss-Prot 53.0
572Phosphoserine (By similarity).Swiss-Prot 53.0
582Phosphoserine.Swiss-Prot 53.0
590Phosphothreonine.Swiss-Prot 53.0
582Phosphoserine15302935;17081983Phospho.ELM 6.0
556Phosphothreonine (CDK1;PLK1)14657031;14657031Phospho.ELM 6.0
559Phosphothreonine (CDK1;PLK1)14657031;14657031Phospho.ELM 6.0
576Phosphothreonine (CDK1)14657031Phospho.ELM 6.0
267Phosphotyrosine14657031Phospho.ELM 6.0
590Phosphothreonine16565220;17081983Phospho.ELM 6.0
587Phosphoserine17081983Phospho.ELM 6.0

Methylation Profile   [Top]

There is no record for CDC23



')