| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 8550 |
Name | MAPKAPK5 |
Synonymous | mitogen-activated protein kinase-activated protein kinase 5;MAPKAPK5;mitogen-activated protein kinase-activated protein kinase 5 |
Definition | MAP kinase-activated protein kinase 5|MAPK-activated protein kinase 5|MAPKAP kinase 5|MAPKAPK-5|p38-regulated/activated protein kinase |
Position | 12q24.13 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | MAPKAPK5(h) + ATP --p38beta2(h)--> MAPKAPK5(h){p} + ADP (phosphorylation) | MAPKAPK5(h) + ATP --p38delta(m)--> MAPKAPK5(h){p} + ADP (phosphorylation) | p38alpha(m) + MAPKAPK5(h) <==> p38alpha(m):MAPKAPK5(h) (binding) | p38beta1(h) + MAPKAPK5(h) <==> p38beta1(h):MAPKAPK5(h) (binding) | MAPKAPK5(h) --> MAPKAPK5(h) (expression). | Hsp27(m) + ATP --MAPKAPK5(h)--> Hsp27(m){p} + ADP (phosphorylation) | Hsp27(h) + ATP --MAPKAPK5(h)--> Hsp27(h){p} + ADP (phosphorylation) | eIF-4E(m.s.) + ATP --MAPKAPK5(h)--> eIF-4E(m.s.){p} + ADP (phosphorylation) | MAPKAPK5(h) --> MAPKAPK5(h) (expression). |
|---|
Post Transcriptional Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 182 | Phosphothreonine. | Swiss-Prot 53.0 | 182 | Phosphothreonine (MAPK1;MAPK14) | 9628874 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr12 |
Promoter: 110763162 - 110765162 | Agilent_014791 |
chr12 |
Promoter: 110763162 - 110765162 | GSE27584 |
chr12 |
Promoter: 110763162 - 110765162 | GSE27584 |
chr12 |
Promoter: 110763162 - 110765162 | Agilent_014791_44K |