Entrez Gene

Basic Information
Gene ID	8535
Name	CBX4
Synonymous	chromobox homolog 4;CBX4;chromobox homolog 4
Definition	E3 SUMO-protein ligase CBX4\|NS5ATP1-binding protein 16\|Pc class 2 homolog\|chromobox homolog 4 (Pc class homolog, Drosophila)\|chromobox protein homolog 4\|polycomb 2 homolog
Position	17q25.3
Gene Type	protein-coding
Gene Regulation:	Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database

Regulation From TransFac database
Transcription Factors [Top]
CtBP1(m.s.) + Pc2-isoform1(h) <==> CtBP1(m.s.):Pc2-isoform1(h) (binding)
Ubc9(m.s.) + Pc2-isoform1(h) <==> Ubc9(m.s.):Pc2-isoform1(h) (binding)
2 Pc2-isoform1(h) <==> (Pc2-isoform1(h))2 (oligomerization)
CBX4(h) --> Pc2-isoform1(h) (expression).
CtBP1(m.s.) + sumo1(m.s.) --Aos1(m.s.):SAE2(m.s.),Ubc9(m.s.),Pc2-isoform1(h)--> CtBP1(m.s.){sumo} (sumoylation)
CtBP1(m.s.) --Pc2-isoform1(h),Ubc9(m.s.){sumo}--> CtBP1(m.s.){sumo} (sumoylation)
cystathionine beta-synthase isoform-1(h) + Pc2(h) <==> cystathionine beta-synthase isoform-1(h):Pc2(h) (binding)
CBX4(h) --> Pc2(h) (expression).
CBX4(h) --> Pc2-isoform2(h) (expression).

Location (AA)	PTM type	Database
Post Transcriptional Modification [Top]
413	Phosphoserine.	Swiss-Prot 53.0
495	Phosphothreonine.	Swiss-Prot 53.0
492	Glycyl lysine isopeptide (Lys-Gly)(interchain with G-Cter in SUMO).	Swiss-Prot 53.0

Transcription Factors [Top]