| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 8349 |
Name | HIST2H2BE |
Synonymous | histone cluster 2, H2be;HIST2H2BE;histone cluster 2, H2be |
Definition | H2B histone family, member Q|histone 2, H2be|histone H2B type 2-E|histone H2B-GL105|histone H2B.q |
Position | 1q21.2 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | HIST2H2BE(h) --> hist2h2be(h) (expression). | sumo1(h) + hist2h2be(h) --> hist2h2be(h){sumo} (sumoylation) | SUMO2(h) + hist2h2be(h) --> hist2h2be(h){sumo2} (sumoylation) | hist2h2be(h) + ubiquitin(h) --E1(m.s.),Ubc5C(m.s.),BARD1(x):brca1(x)--> hist2h2be(h){ub} (ubiquitination) | IRT1(h) + hist2h2be(h) <==> IRT1(h):hist2h2be(h) (binding) | HIST2H2BE(h) --> hist2h2be(h) (expression). |
|---|
Post Transcriptional Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 6 | N6-acetyllysine. | Swiss-Prot 53.0 | 12 | N6-acetyllysine. | Swiss-Prot 53.0 | 13 | N6-acetyllysine. | Swiss-Prot 53.0 | 15 | Phosphoserine (by STK4). | Swiss-Prot 53.0 | 16 | N6-acetyllysine. | Swiss-Prot 53.0 | 17 | N6-acetyllysine. | Swiss-Prot 53.0 | 21 | N6-acetyllysine. | Swiss-Prot 53.0 | 24 | N6-acetyllysine. | Swiss-Prot 53.0 | 47 | N6-methyllysine. | Swiss-Prot 53.0 | 58 | N6,N6-dimethyllysine. | Swiss-Prot 53.0 | 109 | N6-acetyllysine; alternate. | Swiss-Prot 53.0 | 109 | N6-methyllysine; alternate. | Swiss-Prot 53.0 | 121 | Glycyl lysine isopeptide (Lys-Gly)(interchain with G-Cter in ubiquitin). | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr1 |
Promoter: 148124356 - 148126356 | GSE27584 |
chr1 |
Promoter: 148124356 - 148126356 | Agilent_014791_44K |