Cell senescence gene database Home
Cell senescence database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

8091

Name

HMGA2

Synonymous

high mobility group AT-hook 2;HMGA2;high mobility group AT-hook 2

Definition

High-mobility group protein HMGI-C|high mobility group protein HMGI-C|high-mobility group (nonhistone chromosomal) protein isoform I-C

Position

12q15

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors   [Top]

Regulation From TransFac database

HMGI-C(h) --> BCL2A1(h) (DNA binding; transactivation).
HMGA2(h) --> HMGI-C(h) (expression).
HMGA2(h) --> HMGA2(h) (expression).
hsa-let-7b --/ HMGA2(h) (increase of mRNA decay).
hsa-let-7e --/ HMGA2(h) (increase of mRNA decay).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

105Phosphoserine (By similarity).Swiss-Prot 53.0
44Phosphoserine (CDK1)10636877Phospho.ELM 6.0
59Phosphoserine (CDK1)10636877Phospho.ELM 6.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr12

Promoter: 64504344 - 64504388Agilent_014791

chr12

Promoter: 64503007 - 64505007GSE27584

chr12

Promoter: 64503007 - 64505007GSE27584

chr12

Promoter: 64503007 - 64505007E-GEOD-20553

chr12

Promoter: 64503007 - 64505007E-GEOD-20553


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