| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 8091 |
Name | HMGA2 |
Synonymous | high mobility group AT-hook 2;HMGA2;high mobility group AT-hook 2 |
Definition | High-mobility group protein HMGI-C|high mobility group protein HMGI-C|high-mobility group (nonhistone chromosomal) protein isoform I-C |
Position | 12q15 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | HMGI-C(h) --> BCL2A1(h) (DNA binding; transactivation). | HMGA2(h) --> HMGI-C(h) (expression). | HMGA2(h) --> HMGA2(h) (expression). | hsa-let-7b --/ HMGA2(h) (increase of mRNA decay). | hsa-let-7e --/ HMGA2(h) (increase of mRNA decay). |
|---|
Post Transcriptional Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 105 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 44 | Phosphoserine (CDK1) | 10636877 | Phospho.ELM 6.0 | 59 | Phosphoserine (CDK1) | 10636877 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr12 |
Promoter: 64504344 - 64504388 | Agilent_014791 |
chr12 |
Promoter: 64503007 - 64505007 | GSE27584 |
chr12 |
Promoter: 64503007 - 64505007 | GSE27584 |
chr12 |
Promoter: 64503007 - 64505007 | E-GEOD-20553 |
chr12 |
Promoter: 64503007 - 64505007 | E-GEOD-20553 |