| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 7337 |
Name | UBE3A |
Synonymous | ubiquitin protein ligase E3A;UBE3A;ubiquitin protein ligase E3A |
Definition | CTCL tumor antigen se37-2|E6AP ubiquitin-protein ligase|human papilloma virus E6-associated protein|human papillomavirus E6-associated protein|oncogenic protein-associated protein E6-AP|renal carcinoma antigen NY-REN-54|ubiquitin-protein ligase E3A |
Position | 15q11.2 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | UbcH7(h) + E6AP(h) <==> UbcH7(h):E6AP(h) (binding) | Ubc5(h){ub(1)} + E6AP(h) --> Ubc5(h) + E6AP(h){ub(1)} (ubiquitination) | UbcH7(h){ub(1)} + E6AP(h) --> UbcH7(h) + E6AP(h){ub(1)} (ubiquitination) | Ubc5A(h){ub(1)} + E6AP(h) --> Ubc5A(h) + E6AP(h){ub(1)} (ubiquitination) | Ubc5B(h){ub(1)} + E6AP(h) --> Ubc5B(h) + E6AP(h){ub(1)} (ubiquitination) | Ubc5C(h){ub(1)} + E6AP(h) --> Ubc5C(h) + E6AP(h){ub(1)} (ubiquitination) | E6AP(h) + Rad23A(h) <==> E6AP(h):Rad23A(h) (binding) | E6AP(h) + Rad23B(h) <==> E6AP(h):Rad23B(h) (binding) | phosphorylase kinase gamma2(h) + E6AP(h) <==> phosphorylase kinase gamma2(h):E6AP(h) (binding) | MycBP2(h) + E6AP(h) <==> MycBP2(h):E6AP(h) (binding) | phkb(h) + E6AP(h) <==> phkb(h):E6AP(h) (binding) | phka2(h) + E6AP(h) <==> phka2(h):E6AP(h) (binding) | golgin-160(h) + E6AP(h) <==> golgin-160(h):E6AP(h) (binding) | calmodulin2(h) + E6AP(h) <==> calmodulin2(h):E6AP(h) (binding) | psmd3(h) + E6AP(h) <==> psmd3(h):E6AP(h) (binding) | C2orf44(h) + E6AP(h) <==> C2orf44(h):E6AP(h) (binding) | UBE3A(h) --> E6AP(h) (expression). | p53(h) + n ubiquitin(v.s.) --E1(v.s.),Ubc5(h),E6(HPV5),E6AP(h)--> p53(h){ub(n)} (ubiquitination) | Rad23A(h) + n ubiquitin(v.s.) --E1(v.s.),UbcH7(h),E6AP(h),ATP--> Rad23A(h){ub(n)} (ubiquitination) | Rad23B(h) + n ubiquitin(v.s.) --E1(v.s.),UbcH7(h),E6AP(h),ATP--> Rad23B(h){ub(n)} (ubiquitination) | Rad23A(mo) + n ubiquitin(v.s.) --E6AP(h)--> Rad23A(mo){ub(n)} (ubiquitination) | UBE3A(h) --> E6AP-isoform1(h) (expression). | UBE3A(h) --> E6AP-isoform2(h) (expression). | UBE3A(h) --> E6AP-isoform3(h) (expression). |
|---|
Post Transcriptional Modification [Top] | |||
There is no record for UBE3A | |||
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr15 |
Promoter: 23234721 - 23236721 | Agilent_014791 |
chr15 |
Promoter: 23234721 - 23236721 | GSE27584 |
chr15 |
Promoter: 23234721 - 23236721 | Agilent_014791_44K |
chr15 |
Promoter: 23204388 - 23206388 | E-GEOD-20553 |
chr15 |
Promoter: 23201246 - 23203246 | E-GEOD-20553 |
chr15 |
Promoter: 23234721 - 23236721 | E-GEOD-20553 |