Entrez Gene

Basic Information
Gene ID	7295
Name	TXN
Synonymous	thioredoxin;TXN;thioredoxin
Definition	ADF\|ATL-derived factor\|SASP\|TXN delta 3\|surface-associated sulphydryl protein\|thioredoxin delta 3
Position	9q31
Gene Type	protein-coding
Gene Regulation:	Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database

Regulation From TransFac database
Transcription Factors [Top]
GR-alpha(h) + Trx1(h) <==> GR-alpha(h):Trx1(h) (binding)
Trx1(h) --> IkappaB-alpha(h) (activation)
Trx1(h) --> CREB1(h) (transactivation)
Trx1(h) --> HIF-1(h) (redox reaction)
LPTL(h) + Trx1(h) <==> LPTL(h):Trx1(h) (binding)
VHL(h) + Trx1(h) <==> VHL(h):Trx1(h) (binding)
cd40(h) + Trx1(h) <==> cd40(h):Trx1(h) (binding)
GAPD(h) + Trx1(h) <==> GAPD(h):Trx1(h) (binding)
Trx1(h) --> Trx1(h) (translocation)
ASK1(h) + Trx1(h) <==> ASK1(h):Trx1(h) (binding)
H2O2 --> Trx1(h) (activation; translocation)
UV --> Trx1(h) (activation; translocation)
TNF-alpha(h) --> Trx1(h) (activation; translocation)
PMA --> Trx1(h) (activation; translocation)
TXN(h) --> Trx1(h) (expression).
cathepsin-D(h) --/ Trx1(h) (decrease of abundance)
cathepsin-D(m.s.) --/ Trx1(h) (decrease of abundance)
Trx1(h) --> Trx1(h) (translocation)
ASK1(h) + Trx1(h) <==> ASK1(h):Trx1(h) (binding)
2 Trx1(h) <==> (Trx1(h))2 (binding; oligomerization)
TXN(h) --> Trx1(h) (expression).

Location (AA)	PTM type	Literature	Database
Post Transcriptional Modification [Top]
94	N6-acetyllysine.		Swiss-Prot 53.0
100	Phosphothreonine.		Swiss-Prot 53.0
99	Phosphothreonine	16097034	Phospho.ELM 6.0

Transcription Factors [Top]