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Cell senescence database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

7291

Name

TWIST1

Synonymous

twist family bHLH transcription factor 1;TWIST1;twist family bHLH transcription factor 1

Definition

B-HLH DNA binding protein|H-twist|TWIST homolog of drosophila|class A basic helix-loop-helix protein 38|twist basic helix-loop-helix transcription factor 1|twist homolog 1|twist-related protein 1

Position

7p21.2

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors   [Top]

Regulation From TransFac database

HOXA5(h) + TWIST(h) <==> HOXA5(h):TWIST(h) (binding)
TWIST(h) --> GLI1(h) (DNA binding).
TWIST(h) --> CDH2(h) (DNA binding; transactivation).
TWIST1(h) --> TWIST(h) (expression).
EGF(m.s.) --> TWIST(h) (increase of abundance)
CHIP(h) --/ TWIST(h) (decrease of abundance)
SRC3(h) --> TWIST(h) (increase of abundance)
TWIST(h) + E12(h) <==> TWIST(h):E12(h) (binding)
TWIST(h) --> CDH2(h) (DNA binding; transactivation).
TWIST1(h) --> TWIST(h) (expression).

Post Transcriptional Modification   [Top]

There is no record for TWIST1

Methylation Profile   [Top]

Chromosome

Location

Source

chr7

Promoter: 19123320 - 19125320Agilent_014791

chr7

Promoter: 19123320 - 19125320GoldenGate_Methylation_Cancer_Panel_I

chr7

Promoter: 19123320 - 19125320GSE27584

chr7

Promoter: 19123320 - 19125320Agilent_014791_44K

chr7

Promoter: 19123320 - 19125320PMID:20563638

chr7

Promoter: 19123320 - 19125320PMID:15788661

chr7

Promoter: 19123320 - 19125320PMID:15172987

chr7

Promoter: 19123320 - 19125320PMID:15131050

chr7

Promoter: 19123320 - 19125320PMID:15713962

chr7

Promoter: 19123320 - 19125320PMID:15328194


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