Entrez Gene

Basic Information
Gene ID	673
Name	BRAF
Synonymous	B-Raf proto-oncogene, serine/threonine kinase;BRAF;B-Raf proto-oncogene, serine/threonine kinase
Definition	94 kDa B-raf protein\|B-Raf proto-oncogene serine/threonine-protein kinase (p94)\|murine sarcoma viral (v-raf) oncogene homolog B1\|proto-oncogene B-Raf\|serine/threonine-protein kinase B-raf\|v-raf murine sarcoma viral oncogene homolog B\|v-raf murine sarcoma
Position	7q34
Gene Type	protein-coding
Gene Regulation:	Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database

Regulation From TransFac database
Transcription Factors [Top]
B-Raf(h) + ATP --SGK-1(h)--> B-Raf(h){p} + ADP (phosphorylation)
B-Raf(h) + SGK-1(h) <==> B-Raf(h):SGK-1(h) (binding)
B-Raf(h) + Dyrk1A(h) <==> B-Raf(h):Dyrk1A(h) (binding)
14-3-3beta(h) + B-Raf(h) <==> 14-3-3beta(h):B-Raf(h) (binding)
14-3-3gamma(h) + B-Raf(h) <==> 14-3-3gamma(h):B-Raf(h) (binding)
14-3-3tau(h) + B-Raf(h) <==> 14-3-3tau(h):B-Raf(h) (binding)
14-3-3zeta(h) + B-Raf(h) <==> 14-3-3zeta(h):B-Raf(h) (binding)
14-3-3sigma(m.s.) + B-Raf(h) <==> 14-3-3sigma(m.s.):B-Raf(h) (binding)
Sprouty2(h) + B-Raf(h) <==> Sprouty2(h):B-Raf(h) (binding)
B-Raf(h) + MEK(h) <==> B-Raf(h):MEK(h) (binding)
BRAF(h) --> B-Raf(h) (expression).
MEK1(r):MP1(m) + ATP --B-Raf(h)--> MEK1(r){p}:MP1(m) + ADP (phosphorylation)
MEK(m.s.) + ATP --B-Raf(h)--> MEK(m.s.){p} + ADP (phosphorylation)
BRAF(h) --> B-Raf(h) (expression).

Post Transcriptional Modification [Top]
	There is no record for BRAF

Transcription Factors [Top]