Cell senescence gene database Home
Cell senescence database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

6045

Name

RNF2

Synonymous

ring finger protein 2;RNF2;ring finger protein 2

Definition

E3 ubiquitin-protein ligase RING2|HIP2-interacting protein 3|RING finger protein 1B|RING finger protein BAP-1|huntingtin-interacting protein 2-interacting protein 3|protein DinG

Position

1q25.3

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors   [Top]

Regulation From TransFac database

RING1B(h) --Caspase-3(h)--> RING1B-p18(h) + protein remnants (cleavage)
RING1B(h) --Caspase-9(h)--> RING1B-p22(h) + RING1B-p15(h) + protein remnants (cleavage)
RING1B(h) --Caspase(h)--> RING1B-p18(h) + protein remnants (cleavage)
RING1B(h) --Caspase-9(h)--> RING1B-p22(h) + protein remnants (cleavage)
RNF2(h) --> RING1B(h) (expression).
E2F-1(h) + RING1B(h) <==> E2F-1(h):RING1B(h) (binding)
E2F-3a(h) + RING1B(h) <==> E2F-3a(h):RING1B(h) (binding)
RING1B(h) --Caspase(h)--> RING1B-p18(h) + protein remnants (cleavage)
RNF2(h) --> RING1B(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

168Phosphoserine.Swiss-Prot 53.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr1

Promoter: 183279674 - 183281674Agilent_014791

chr1

Promoter: 183279674 - 183281674GSE27584

chr1

Promoter: 183279674 - 183281674Agilent_014791_44K


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