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Cell senescence database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

571

Name

BACH1

Synonymous

BTB and CNC homology 1, basic leucine zipper transcription factor 1;BACH1;BTB and CNC homology 1, basic leucine zipper transcription factor 1

Definition

basic region leucine zipper transcriptional regulator BACH1|transcription regulator protein BACH1

Position

21q22.11

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors   [Top]

Regulation From TransFac database

Bach1(h) --> GLOB-B(c) (DNA binding).
Bach1(h) + Bach1t(h) <==> Bach1(h):Bach1t(h) (binding).
CREBPA-Alpha(h) + Bach1(h) <==> CREBPA-Alpha(h):Bach1(h) (binding)
MafG(h) + Bach1(h) <==> MafG(h):Bach1(h) (binding)
MafK(h) + Bach1(h) <==> MafK(h):Bach1(h) (binding)
Bach1(h) + c-MAF-isoform2(h) <==> Bach1(h):c-MAF-isoform2(h) (binding)
Bach1(h) + MafB(h) <==> Bach1(h):MafB(h) (binding)
ATF-1(h) + Bach1(h) <==> ATF-1(h):Bach1(h) (binding)
CREM-Ia(h) + Bach1(h) <==> CREM-Ia(h):Bach1(h) (binding)
ATFa-isoform3(h) + Bach1(h) <==> ATFa-isoform3(h):Bach1(h) (binding)
ATF-2-xbb4(h) + Bach1(h) <==> ATF-2-xbb4(h):Bach1(h) (binding)
Bach1(h) --> Bach1(h) (expression).
Bach1(h) + Bach1t(h) <==> Bach1(h):Bach1t(h) (binding).
Bach1(h) --> Bach1t(h) (expression).
p300(h) + TRAP80(h) + DRIP100(h) + DRIP130(h) + Bach1(h) + DRIP205(h) + TRAP240(h) + brca1(h) <==> p300(h):TRAP80(h):DRIP100(h):DRIP130(h):Bach1(h):DRIP205(h):TRAP240(h):brca1(h) (binding)
brca1(m.s.) + Bach1(h) <==> brca1(m.s.):Bach1(h) (binding)
brca1(h) + Bach1(h) <==> brca1(h):Bach1(h) (binding)
BARD1(h) + BRCA2(h) + brca1(h) + Bach1(h) + MLH1(h) + tubulin(h) + CtIP(h) <==> BARD1(h):BRCA2(h):brca1(h):Bach1(h):MLH1(h):tubulin(h):CtIP(h) (binding)
Mre11(h) + CtIP(h) + Bach1(h) + Rad50(h) + BARD1(h) <==> Mre11(h):CtIP(h):Bach1(h):Rad50(h):BARD1(h) (binding)
Mre11(h) + NBS1(h) + Bach1(h) + Rad50(h) + TOP2BP1(h) + BARD1(h) <==> Mre11(h):NBS1(h):Bach1(h):Rad50(h):TOP2BP1(h):BARD1(h) (binding)
Bach1(h) + TOP2BP1(h) + brca1(h) + BARD1(h) <==> Bach1(h):TOP2BP1(h):brca1(h):BARD1(h) (binding)
MLH1(h) + TOP2BP1(h) + Bach1(h) + brca1(h) <==> MLH1(h):TOP2BP1(h):Bach1(h):brca1(h) (binding)
Bach1(h) + brca1(h) <==> Bach1(h):brca1(h) (binding)
Bach1(h) + RAP80(m.s.) <==> Bach1(h):RAP80(m.s.) (binding)
Bach1(h) + ATP --> Bach1(h){pS} + ADP (phosphorylation)
BARD1(h) + Bach1(h) + brca1(h) + BRCA2(h) <==> BARD1(h):Bach1(h):brca1(h):BRCA2(h) (binding)
BRCC36(h) + BRE(h) + Bach1(h) + BRCA2(h) + brca1(h) + BARD1(m.s.) <==> BRCC36(h):BRE(h):Bach1(h):BRCA2(h):brca1(h):BARD1(m.s.) (binding)
Bach1(h) + ATP --> Bach1(h){p} + ADP (phosphorylation)
Bach1(h) --> Bach1(h) (expression).
Bach1(h) --> Bach1(h) (expression).
kshv-miR-K12-11 --/ Bach1(h) (translational repression).
hsa-miR-155 --/ Bach1(h) (translational repression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

196Phosphoserine.Swiss-Prot 53.0
445Phosphoserine.Swiss-Prot 53.0
445Phosphoserine15302935Phospho.ELM 6.0
196Phosphoserine15302935Phospho.ELM 6.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr21

Promoter: 29597931 - 29599931Agilent_014791

chr21

Promoter: 29591591 - 29593591Agilent_014791

chr21

Promoter: 29592108 - 29594108Agilent_014791

chr21

Promoter: 29592108 - 29594108GSE27584

chr21

Promoter: 29591591 - 29593591GSE27584

chr21

Promoter: 29591591 - 29593591Agilent_014791_44K

chr21

Promoter: 29592108 - 29594108Agilent_014791_44K

chr21

Promoter: 29591591 - 29593591Agilent_014791

chr21

Promoter: 29592108 - 29594108Agilent_014791


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