Entrez Gene

Basic Information
Gene ID	5600
Name	MAPK11
Synonymous	mitogen-activated protein kinase 11;MAPK11;mitogen-activated protein kinase 11
Definition	MAP kinase 11\|MAP kinase p38 beta\|mitogen-activated protein kinase p38 beta\|mitogen-activated protein kinase p38-2\|stress-activated protein kinase-2\|stress-activated protein kinase-2b
Position	22q13.33
Gene Type	protein-coding
Gene Regulation:	Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database

Regulation From TransFac database
Transcription Factors [Top]
p38beta2(h) + ATP --MKK6(h){p}--> p38beta2(h){p} + ADP (phosphorylation)
MAPK11(h) --> p38beta2(h) (expression).
STAT1(h) + ATP --p38beta2(h)--> STAT1(h){pS727} + ADP (phosphorylation)
MAPKAPK5(h) + ATP --p38beta2(h)--> MAPKAPK5(h){p} + ADP (phosphorylation)
MEF2A-isoform1(h) + ATP --p38beta2(h)--> MEF2A-isoform1(h){p} + ADP (phosphorylation)
MEF-2C(h) + ATP --p38beta2(h)--> MEF-2C(h){p} + ADP (phosphorylation)
p38beta1(h) + ATP --MKK6-isoform1(h)--> p38beta1(h){p} + ADP (phosphorylation)
p38beta1(h) + MAPKAPK5(h) <==> p38beta1(h):MAPKAPK5(h) (binding)
MAPK11(h) --> p38beta1(h) (expression).
Tau(h) + NTP --p38beta1(h)--> Tau(h){p} + NDP (phosphorylation)
MSK1(h) + ATP --p38beta1(h)--> MSK1(h){p} + ADP (phosphorylation)
MAPKAPK2(h) + ATP --p38beta1(h)--> MAPKAPK2(h){p} + ADP (phosphorylation)
p38beta(h) + 2 ATP --> p38beta(h){pT}{pY} + 2 ADP (phosphorylation)
p38beta(h) + ATP --> p38beta(h){p} + ADP (phosphorylation)
MAPK11(h) --> p38beta(h) (expression).
TAB1(h) + 3 ATP --p38beta(h)--> TAB1(h){pS423}{pT431}{pS438} + 3 ADP (phosphorylation)

Location (AA)	PTM type	Database
Post Transcriptional Modification [Top]
180	Phosphothreonine (Probable).	Swiss-Prot 53.0
182	Phosphotyrosine (Probable).	Swiss-Prot 53.0

Transcription Factors [Top]