| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 5329 |
Name | PLAUR |
Synonymous | plasminogen activator, urokinase receptor;PLAUR;plasminogen activator, urokinase receptor |
Definition | monocyte activation antigen Mo3|u-plasminogen activator receptor form 2|urokinase plasminogen activator surface receptor|urokinase-type plasminogen activator (uPA) receptor |
Position | 19q13 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | uPAR(h) + nucleolin(h){p} <==> uPAR(h):nucleolin(h){p} (binding) | CKII-alpha(h):CKII-alpha2(h):(CKII-beta(h))2 + uPAR(h) <==> CKII-alpha(h):CKII-alpha2(h):(CKII-beta(h))2:uPAR(h) (binding) | Jak1(h) + uPAR(h) <==> Jak1(h):uPAR(h) (binding) | Tyk2(h) + uPAR(h) <==> Tyk2(h):uPAR(h) (binding) | Fyn(h) + uPAR(h) <==> Fyn(h):uPAR(h) (binding) | Lyn(h) + uPAR(h) <==> Lyn(h):uPAR(h) (binding) | Fgr(h) + uPAR(h) <==> Fgr(h):uPAR(h) (binding) | Hck(h) + uPAR(h) <==> Hck(h):uPAR(h) (binding) | uPAR(h) + STAT1(h) <==> uPAR(h):STAT1(h) (binding) | uPAR(h) + gp130(h) <==> uPAR(h):gp130(h) (binding) | uPAR(h) --cathepsin G(h)--> uPARp54(h) (cleavage) | uPAR(h) --elastase-2A(h)--> uPARp15(h) (cleavage) | uPAR(h) --cathepsin G(h)--> uPARp38(h) (cleavage) | uPAR(h) + Factor XIIa(h) <==> uPAR(h):Factor XIIa(h) (binding) | uPAR(h) + L-selectin(h) <==> uPAR(h):L-selectin(h) (binding) | CD11B(h) + uPAR(h) <==> CD11B(h):uPAR(h) (binding) | uPAR(h) + beta1-integrin(h) <==> uPAR(h):beta1-integrin(h) (binding) | uPAR(h) + uPA(m.s.) <==> uPAR(h):uPA(m.s.) (binding) | PLAUR(h) --> uPAR(h) (expression). | IFNgamma(h) --> uPAR(h) (increase of abundance) | IFNalpha2b(h) --> uPAR(h) (increase of abundance) | PLAUR(h) --> uPAR-isoform1(h) (expression). | PLAUR(h) --> uPAR-xbb1(h) (expression). | PLAUR(h) --> uPAR-isoform2(h) (expression). | PLAUR(h) --> uPAR-isoform3(h) (expression). |
|---|
Post Transcriptional Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 74 | N-linked (GlcNAc...). | Swiss-Prot 53.0 | 184 | N-linked (GlcNAc...). | Swiss-Prot 53.0 | 194 | N-linked (GlcNAc...). | Swiss-Prot 53.0 | 222 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 255 | N-linked (GlcNAc...). | Swiss-Prot 53.0 | 305 | GPI-anchor amidated glycine (Probable). | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr19 |
Promoter: 48865842 - 48867842 | GoldenGate_Methylation_Cancer_Panel_I |
chr19 |
Promoter: 48865842 - 48867842 | GoldenGate_Methylation_Cancer_Panel_I |
chr19 |
Promoter: 48865842 - 48867842 | GoldenGate_Methylation_Cancer_Panel_I |
chr19 |
Promoter: 48865842 - 48867842 | GSE27584 |
chr19 |
Promoter: 48865842 - 48867842 | GSE27584 |
chr19 |
Promoter: 48865842 - 48867842 | GSE27584 |