Entrez Gene

Basic Information
Gene ID	51434
Name	ANAPC7
Synonymous	anaphase promoting complex subunit 7;ANAPC7;anaphase promoting complex subunit 7
Definition	anaphase-promoting complex subunit 7\|cyclosome subunit 7
Position	12q24.11
Gene Type	protein-coding
Gene Regulation:	Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database

Regulation From TransFac database
Transcription Factors [Top]
APC7(h) + ATP --plk1(h)--> APC7(h){pS17} + ADP (phosphorylation)
APC7(h) + ATP --plk1(h)--> APC7(h){pS23} + ADP (phosphorylation)
APC7(h) + ATP --plk1(h)--> APC7(h){pS30} + ADP (phosphorylation)
APC7(h) + Cdc20(h) + MAD2(h) + Bub3(h) + BubR1(h) <==> APC7(h):Cdc20(h):MAD2(h):Bub3(h):BubR1(h) (binding)
APC7(h) + p300(h) <==> APC7(h):p300(h) (binding)
CBP(h) + APC7(h) <==> CBP(h):APC7(h) (binding)
APC7(h) --> CDKN1A(h) (transactivation)
APC7(h) --> p21Cip1(h) (increase of abundance)
Mps1(h) + APC7(h) <==> Mps1(h):APC7(h) (binding)
Emi1(h) + APC7(h) <==> Emi1(h):APC7(h) (binding)
APC1(h) + APC11(h) + APC2(h) + APC4(h) + APC5(h) + APC7(h) + Cdc16(h) + Cdc23(h) + Emi1(h) + Fzr1(h) <==> APC1(h):APC2(h):APC4(h):APC5(h):Cdc16(h):APC7(h):Cdc23(h):APC11(h):Fzr1(h):Emi1(h) (binding)
APC7(h) + Fzr1(m.s.) <==> APC7(h):Fzr1(m.s.) (binding)
APC7(h) + Cdc27(h) <==> APC7(h):Cdc27(h) (binding)
APC7(h) + APC2(h) <==> APC7(h):APC2(h) (binding)
BubR1(h) + APC7(h) <==> BubR1(h):APC7(h) (binding)
ANAPC7(h) --> APC7(h) (expression).
ANAPC7(h) --> APC7(h) (expression).

Location (AA)	PTM type	Literature	Database
Post Transcriptional Modification [Top]
17	Phosphoserine (PLK1)	14657031	Phospho.ELM 6.0
23	Phosphoserine (PLK1)	14657031	Phospho.ELM 6.0
30	Phosphoserine (PLK1)	14657031	Phospho.ELM 6.0

Transcription Factors [Top]