Entrez Gene

Basic Information
Gene ID	4282
Name	MIF
Synonymous	macrophage migration inhibitory factor (glycosylation-inhibiting factor);MIF;macrophage migration inhibitory factor (glycosylation-inhibiting factor)
Definition	L-dopachrome isomerase\|L-dopachrome tautomerase\|macrophage migration inhibitory factor\|phenylpyruvate tautomerase
Position	22q11.23
Gene Type	protein-coding
Gene Regulation:	Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database

Regulation From TransFac database
Transcription Factors [Top]
DHLAG(m.s.) + GIF(h) <==> DHLAG(m.s.):GIF(h) (binding)
GIF(h) + NDKA(h) <==> GIF(h):NDKA(h) (binding)
GIF(h) + NDKA(h){p} <==> GIF(h):NDKA(h){p} (binding)
p53(m.s.) + GIF(h) <==> p53(m.s.):GIF(h) (binding)
GIF(h) --> p53(m.s.){ub} (increase of ubiquitination)
GIF(h) + JAB1(m.s.) <==> GIF(h):JAB1(m.s.) (binding)
GIF(h) --> JAB1(m.s.):p27Kip1(m.s.) (decrease of binding)
GIF(h) --> MMP1(h) (transactivation)
GIF(h) --> mmp1(h) (increase of abundance)
GIF(h) --> PKC(h){p} (increase of phosphorylation)
GIF(h) --> PKCdelta(h){pT507} (increase of phosphorylation)
GIF(h) --> PKCdelta(h){pS645} (increase of phosphorylation)
GIF(h) --> Raf(h){p} (increase of phosphorylation)
GIF(h) --> MAPK(h){p} (increase of phosphorylation)
MIF(h) --> GIF(h) (expression).
DustyPK(h) + GIF(h) <==> DustyPK(h):GIF(h) (binding)
FGFIBP(h) + GIF(h) <==> FGFIBP(h):GIF(h) (binding)
DCR2(h) + GIF(h) <==> DCR2(h):GIF(h) (binding)
GIF(h) + GRASP55(h) <==> GIF(h):GRASP55(h) (binding)
GIF(h) + NDKA(h) <==> GIF(h):NDKA(h) (binding)
GIF(h) + p53(h) <==> GIF(h):p53(h) (binding)
GIF(h) --/ p53(h) (decrease of abundance)
GIF(h) --/ p21Cip1(h) (decrease of abundance)
GIF(h) --/ mdm2(h) (decrease of abundance)
GIF(h) --/ Bax(h) (decrease of abundance)
GIF(h) + mdm2(h) + p53(h) <==> GIF(h):mdm2(h):p53(h) (binding)
MIF(h) --> GIF(h) (expression).

Location (AA)	PTM type	Literature	Database
Post Transcriptional Modification [Top]
37	Phosphotyrosine.		Swiss-Prot 53.0

Transcription Factors [Top]