Entrez Gene

Basic Information
Gene ID	3315
Name	HSPB1
Synonymous	heat shock 27kDa protein 1;HSPB1;heat shock 27kDa protein 1
Definition	28 kDa heat shock protein\|HSP 27\|epididymis secretory protein Li 102\|estrogen-regulated 24 kDa protein\|heat shock 27 kDa protein\|heat shock 27kD protein 1\|heat shock protein beta-1\|stress-responsive protein 27
Position	7q11.23
Gene Type	protein-coding
Gene Regulation:	Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database

Regulation From TransFac database
Transcription Factors [Top]
Hsp27(h) + Cytochrome C(h) <==> Hsp27(h):Cytochrome C(h) (binding)
Hsp27(h) + Cytochrome C(ho) <==> Hsp27(h):Cytochrome C(ho) (binding)
Hsp27(h) + ATP --MAPKAPK2(h){p}--> Hsp27(h){p} + ADP (phosphorylation)
Hsp27(h) + ATP --MAPKAPK5(h)--> Hsp27(h){p} + ADP (phosphorylation)
Hsp27(h) + MAPKAPK2(h) + AKT(h) + p38(h) <==> Hsp27(h):MAPKAPK2(h):AKT(h):p38(h) (binding)
AKT(m.s.) + Hsp27(h) <==> AKT(m.s.):Hsp27(h) (binding)
MAPKAPK2(m.s.) + Hsp27(h) <==> MAPKAPK2(m.s.):Hsp27(h) (binding)
NRAGE(h) + Hsp27(h) <==> NRAGE(h):Hsp27(h) (binding)
ILK(h) + Hsp27(h) <==> ILK(h):Hsp27(h) (binding)
Hsp27(h) + p53(h) <==> Hsp27(h):p53(h) (binding)
Hsp27(h) + MED31(h) <==> Hsp27(h):MED31(h) (binding)
Hsp27(h) + RIF1(h) <==> Hsp27(h):RIF1(h) (binding)
Hsp27(h) + c7orf64(h) <==> Hsp27(h):c7orf64(h) (binding)
HSPB1(h) --> Hsp27(h) (expression).
HSPB1(h) --> Hsp27(h) (expression).

Location (AA)	PTM type	Literature	Database
Post Transcriptional Modification [Top]
15	Phosphoserine.		Swiss-Prot 53.0
26	Phosphoserine (By similarity).		Swiss-Prot 53.0
65	Phosphoserine.		Swiss-Prot 53.0
78	Phosphoserine.		Swiss-Prot 53.0
82	Phosphoserine.		Swiss-Prot 53.0
83	Phosphoserine.		Swiss-Prot 53.0
123	N6-acetyllysine.		Swiss-Prot 53.0
78	Phosphoserine (MAPKAPK2;p70)	93076920;15302935;1730670;10383393;12096113;113835	Phospho.ELM 6.0
82	Phosphoserine (PKD1;MAPKAPK)	93076920;15302935;16097034;15728188;1332886;173067	Phospho.ELM 6.0
15	Phosphoserine (MAPKAPK2;PKA)	93076920;15302935;10383393;12096113;11383510	Phospho.ELM 6.0
83	Phosphoserine	15302935;17081983	Phospho.ELM 6.0
86	Phosphoserine	15302935	Phospho.ELM 6.0
65	Phosphoserine	17081983	Phospho.ELM 6.0
91	Phosphothreonine	17081983	Phospho.ELM 6.0

Transcription Factors [Top]