Entrez Gene

Basic Information
Gene ID	3265
Name	HRAS
Synonymous	Harvey rat sarcoma viral oncogene homolog;HRAS;Harvey rat sarcoma viral oncogene homolog
Definition	GTP- and GDP-binding peptide B\|GTPase HRas\|Ha-Ras1 proto-oncoprotein\|Harvey rat sarcoma viral oncoprotein\|Ras family small GTP binding protein H-Ras\|c-has/bas p21 protein\|c-ras-Ki-2 activated oncogene\|p19 H-RasIDX protein\|transformation gene: oncogene HAM
Position	11p15.5
Gene Type	protein-coding
Gene Regulation:	Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database

Regulation From TransFac database
Transcription Factors [Top]
H-Ras(h) + GDP <==> H-Ras(h):GDP (binding)
C3G(h) + H-Ras(h) <==> C3G(h):H-Ras(h) (binding)
Raf-1(h) + H-Ras(h) <==> Raf-1(h):H-Ras(h) (binding)
TPR1(h) + H-Ras(h) <==> TPR1(h):H-Ras(h) (binding)
H-Ras(h) + caveolin-1(h) <==> H-Ras(h):caveolin-1(h) (binding)
H-Ras(h) + RIN1(h) <==> H-Ras(h):RIN1(h) (binding)
Cdc25(v.s.) + H-Ras(h) <==> Cdc25(v.s.):H-Ras(h) (binding)
H-Ras(h) + Raf-1(m.s.) <==> H-Ras(h):Raf-1(m.s.) (binding)
H-Ras(h) --/ ING2(h) (decrease of abundance)
H-Ras(h) --> p21Cip1(h) (increase of abundance)
H-Ras(h) --> p16INK4a(h) (increase of abundance)
HRAS(h) --> H-Ras(h) (expression).
PDGFB(m.s.) --> H-Ras(h) (increase of abundance)
H2O2 --> H-Ras(h) (increase of abundance)
apc(h) + beta-catenin(m) <==> apc(h):beta-catenin(m) (binding)
H-Ras(h) --> c-Jun(mo) (increase of abundance)
HRAS(h) --> H-Ras(h) (expression).
HRAS(h) --> HRAS_1(h) (expression).
hsa-let-7a --/ HRAS_1(h) (predicted)
HRAS(h) --> HRAS_2(h) (expression).
hsa-let-7a --/ HRAS_2(h) (predicted)

Location (AA)	PTM type	Literature	Database
Post Transcriptional Modification [Top]
181	S-palmitoyl cysteine.		Swiss-Prot 53.0
184	S-palmitoyl cysteine.		Swiss-Prot 53.0
186	Cysteine methyl ester.		Swiss-Prot 53.0
186	S-farnesyl cysteine.		Swiss-Prot 53.0
35	Phosphothreonine	9264402	Phospho.ELM 6.0

Transcription Factors [Top]