Cell senescence gene database Home
Cell senescence database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

29843

Name

SENP1

Synonymous

SUMO1/sentrin specific peptidase 1;SENP1;SUMO1/sentrin specific peptidase 1

Definition

SUMO1/sentrin specific protease 1|sentrin-specific protease 1|sentrin/SUMO-specific protease SENP1

Position

12q13.1

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors   [Top]

Regulation From TransFac database

SENP1(h) --> senp1-isoform1(h) (expression).
IKK-gamma(h){sumo} --senp1-isoform1(h)--> sumo1(h) + IKK-gamma(h) (desumoylation)
senp1(h) --> kallikrein-3(h) (increase of abundance)
senp1(h) --> c-Jun(h) (increase of abundance)
SENP1(h) --> senp1(h) (expression).
Ca --> senp1(h) (increase of abundance)
RanGAP1(h){sumo} --senp1(h)--> RanGAP1(h) + SUMO1-NTF(h) (desumoylation)
RanGAP1(m){sumo2} --senp1(h)--> SUMO2-NTF(h) + RanGAP1(h) (desumoylation)
RanGAP1(m){sumo3} --senp1(h)--> RanGAP1(h) + sumo3-NTF(h) (desumoylation)
sumo1(m.s.) --senp1(h)--> sumo1-NTF(m.s.) + protein remnants (cleavage)
SUMO2(h) --senp1(h)--> protein remnants + SUMO2-NTF(h) (cleavage)
sumo3(h) --senp1(h)--> protein remnants + sumo3-NTF(h) (cleavage)
SENP1(h) --> senp1-isoform2(h) (expression).

Post Transcriptional Modification   [Top]

There is no record for SENP1

Methylation Profile   [Top]

Chromosome

Location

Source

chr12

Promoter: 46785408 - 46787408Agilent_014791

chr12

Promoter: 46785408 - 46787408GSE27584

chr12

Promoter: 46785408 - 46787408Agilent_014791_44K


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