| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 286053 |
Name | NSMCE2 |
Synonymous | non-SMC element 2, MMS21 homolog (S. cerevisiae);NSMCE2;non-SMC element 2, MMS21 homolog (S. cerevisiae) |
Definition | E3 SUMO-protein ligase NSE2|MMS21 homolog|hMMS21|methyl methanesulfonate sensitivity gene 21|non-SMC element 2 homolog|non-structural maintenance of chromosomes element 2 homolog|zinc finger, MIZ-type containing 7 |
Position | 8q24.13 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | NSE2(h) + SMC5(h) <==> NSE2(h):SMC5(h) (binding) | NSE2(h) + sumo1(h) --Aos1(h):SAE2(h),Ubc9(h)--> NSE2(h){sumo} (sumoylation) | NSE2(h) + sumo1(m.s.) --> NSE2(h){sumo} (sumoylation) | NSMCE2(h) --> NSE2(h) (expression). | TRAX(m.s.) + sumo1(h) --Aos1(h):SAE2(h),NSE2(h),Ubc9(h)--> TRAX(m.s.){sumo} (sumoylation) | SMC6(h) + sumo1(m.s.) --NSE2(h)--> SMC6(h){sumo} (sumoylation) | NSE2(h) + SMC5(h) <==> NSE2(h):SMC5(h) (binding) | NSE2(h) --> brca1(h){sumo} (decrease of sumoylation) | NSE2(h) --> brca1(h){sumo2} (decrease of sumoylation) | NSMCE2(h) --> NSE2(h) (expression). |
|---|
Post Transcriptional Modification [Top] | |||
There is no record for NSMCE2 | |||
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr8 |
Promoter: 126171777 - 126173777 | GSE27584 |
chr8 |
Promoter: 126171777 - 126173777 | Agilent_014791_44K |