| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 2597 |
Name | GAPDH |
Synonymous | glyceraldehyde-3-phosphate dehydrogenase;GAPDH;glyceraldehyde-3-phosphate dehydrogenase |
Definition | aging-associated gene 9 protein|epididymis secretory sperm binding protein Li 162eP|peptidyl-cysteine S-nitrosylase GAPDH |
Position | 12p13 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | GAPD(h) + ATP --PKCiota(m.s.)--> GAPD(h){p} + ADP (phosphorylation) | GAPD(h) + RAB2(m.s.) <==> GAPD(h):RAB2(m.s.) (binding) | Tip60(h) + GAPD(h) <==> Tip60(h):GAPD(h) (binding) | GAPDH(h) --> GAPD(h) (expression). | PML(h) + GAPD(h) <==> PML(h):GAPD(h) (binding) | RAB2(h) + GAPD(h) <==> GAPD(h):RAB2(h) (binding) | Hsp70(h) + STIP1(h) + GAPD(h) + NDPKB(h) + NDKA(h) <==> Hsp70(h):STIP1(h):GAPD(h):NDPKB(h):NDKA(h) (binding) | GAPD(h) + Oct-1(h) <==> GAPD(h):Oct-1(h) (binding) | NPAT(h) + GAPD(h) <==> NPAT(h):GAPD(h) (binding) | STIP1(h) + GAPD(h) <==> STIP1(h):GAPD(h) (binding) | NDKA(h) + GAPD(h) <==> NDKA(h):GAPD(h) (binding) | NDPKB(h) + GAPD(h) <==> NDPKB(h):GAPD(h) (binding) | GAPD(h) --> H2B(h) (transactivation) | NDPKB(h) + NDKA(h) + GAPD(h) + STIP1(h) + NPAT(m.s.) <==> NDPKB(h):NDKA(h):GAPD(h):STIP1(h):NPAT(m.s.) (binding) | ErbB1(h) + GAPD(h) <==> ErbB1(h):GAPD(h) (binding) | GAPD(h) + qrich2(h) <==> GAPD(h):qrich2(h) (binding) | GAPD(h) + Trx1(h) <==> GAPD(h):Trx1(h) (binding) | GAPD(h) + MO15(h) <==> GAPD(h):MO15(h) (binding) | FXR(h) + GAPD(h) <==> FXR(h):GAPD(h) (binding) | HNF4gamma(h) + GAPD(h) <==> HNF4gamma(h):GAPD(h) (binding) | RPA2(h) + GAPD(h) <==> RPA2(h):GAPD(h) (binding) | laminin-alpha4(h) + GAPD(h) <==> laminin-alpha4(h):GAPD(h) (binding) | platelet-activating factor acetylhydrolase IB subunit gamma(h) + GAPD(h) <==> platelet-activating factor acetylhydrolase IB subunit gamma(h):GAPD(h) (binding) | CAP3(h) + GAPD(h) <==> CAP3(h):GAPD(h) (binding) | S9(h) + GAPD(h) <==> S9(h):GAPD(h) (binding) | TK1(h) + GAPD(h) <==> TK1(h):GAPD(h) (binding) | ARFRP2(h) + GAPD(h) <==> ARFRP2(h):GAPD(h) (binding) | BTBD2(h) + GAPD(h) <==> BTBD2(h):GAPD(h) (binding) | CNR1(h) + GAPD(h) <==> CNR1(h):GAPD(h) (binding) | Prdx1(h) + GAPD(h) <==> Prdx1(h):GAPD(h) (binding) | hbxip(h) + GAPD(h) <==> hbxip(h):GAPD(h) (binding) | GAPDH(h) --> GAPD(h) (expression). |
|---|
Post Transcriptional Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 42 | Phosphotyrosine. | Swiss-Prot 53.0 | 83 | Phosphoserine. | Swiss-Prot 53.0 | 211 | Phosphothreonine (By similarity). | Swiss-Prot 53.0 | 82 | Phosphoserine | 17081983 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr12 |
Promoter: 6512418 - 6514418 | Agilent_014791 |
chr12 |
Promoter: 6512418 - 6514418 | GSE27584 |
chr12 |
Promoter: 6512418 - 6514418 | Agilent_014791_44K |