| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 2247 |
Name | FGF2 |
Synonymous | fibroblast growth factor 2 (basic);FGF2;fibroblast growth factor 2 (basic) |
Definition | basic fibroblast growth factor bFGF|fibroblast growth factor 2|heparin-binding growth factor 2|prostatropin |
Position | 4q26 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | FGF-2(h) + FGF-BP(h) <==> FGF-2(h):FGF-BP(h) (binding) | CFR(c) + FGF-2(h) <==> CFR(c):FGF-2(h) (binding) | FGF-2(h) + adiponectin(m) <==> FGF-2(h):adiponectin(m) (binding) | FGF-2(h) --> PLCgamma1(r){pY} (increase of phosphorylation) | FGF-2(h) --> p65PAK(m.s.) (translocation) | FGF-2(h) --> eNOS(ha):caveolin-1(ha) (decrease of binding) | FGF-2(h) --> ERK(h){p} (increase of phosphorylation) | FGF-2(h) --> RSK1(h){p} (increase of phosphorylation) | FGF-2(h) --> CREB1(h){pS133} (increase of phosphorylation) | FGF-2(h) --> ERK2(m.s.){p} (increase of phosphorylation) | FGF2(h) --> FGF-2(h) (expression). | fgf2-isoform2(h) --> LIMK1(r){pS}{pT} (increase of phosphorylation) | fgf2-isoform2(h) --/ A2(1) COL(m) (transrepression) | fgf2-isoform2(h) + api5(h) <==> fgf2-isoform2(h):api5(h) (binding) | fgf2-isoform2(h) + api5(m.s.) <==> fgf2-isoform2(h):api5(m.s.) (binding) | FGF2(h) --> fgf2-isoform2(h) (expression). | FGF2(h) --> fgf2-isoform1(h) (expression). | FGF2(h) --> fgf2-isoform3(h) (expression). |
|---|
Post Transcriptional Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 73 | Phosphoserine (PKC alpha) | 2541433 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr4 |
Promoter: 123965813 - 123967813 | Agilent_014791 |
chr4 |
Promoter: 123965813 - 123967813 | GoldenGate_Methylation_Cancer_Panel_I |
chr4 |
Promoter: 123965813 - 123967813 | GSE27584 |
chr4 |
Promoter: 123965813 - 123967813 | Agilent_014791_44K |