Entrez Gene

Basic Information
Gene ID	2022
Name	ENG
Synonymous	endoglin;ENG;endoglin
Definition	CD105 antigen
Position	9q34.11
Gene Type	protein-coding
Gene Regulation:	Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database

Regulation From TransFac database
Transcription Factors [Top]
TGFbetaR-I(h) + endoglin(h) <==> TGFbetaR-I(h):endoglin(h) (binding)
TGFbetaR-II(h) + endoglin(h) <==> TGFbetaR-II(h):endoglin(h) (binding)
endoglin(h) + ATP --TGFbetaR-I(h)--> endoglin(h){p} + ADP (phosphorylation)
endoglin(h) + ATP --TGFbetaR-II(h)--> endoglin(h){p} + ADP (phosphorylation)
endoglin(h) --> eNOS(h) (activation; increase of abundance)
endoglin(h) + Hsp90(h) + caveolin-1(h) + eNOS(h) <==> endoglin(h):Hsp90(h):caveolin-1(h):eNOS(h) (binding)
ENG(h) --> endoglin(h) (expression).
ENG(h) --> endoglin(h) (expression).

Location (AA)	PTM type	Database
Post Transcriptional Modification [Top]
88	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0
102	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0
121	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0
134	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0
307	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0

Transcription Factors [Top]