| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 1984 |
Name | EIF5A |
Synonymous | eukaryotic translation initiation factor 5A;EIF5A;eukaryotic translation initiation factor 5A |
Definition | eIF-4D|eIF-5A-1|eIF-5A1|eukaryotic initiation factor 5A|eukaryotic translation initiation factor 5A-1|rev-binding factor |
Position | 17p13-p12 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | Syntenin(h) + EIF5A1-isoform1(h) <==> Syntenin(h):EIF5A1-isoform1(h) (binding) | EIF5A1-isoform1(h) + Syntenin(h) <==> EIF5A1-isoform1(h):Syntenin(h) (binding) | EIF5A1-isoform1(h) --> p53(h) (increase of abundance). | EIF5A1-isoform1(h) --> Bax(h) (increase of abundance) | EIF5A1-isoform1(h) --> p21Cip1(h) (increase of abundance) | EIF5A1-isoform1(h) --> mdm2(h) (increase of abundance) | EIF5A1-isoform1(h) --> TP53(h) (transactivation) | EIF5A1-isoform1(h) --> p53(h){pS6}{pS392} (increase of phosphorylation) | EIF5A(h) --> EIF5A1-isoform1(h) (expression). | EIF5A1(h) + Syntenin(h) <==> EIF5A1(h):Syntenin(h) (binding) | EIF5A1(h) --> p53(h) (increase of abundance) | EIF5A(h) --> EIF5A1(h) (expression). | EIF5A(h) --> EIF5A1-isoform2(h) (expression). |
|---|
Post Transcriptional Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 2 | Blocked amino end (Ala) (Probable). | Swiss-Prot 53.0 | 50 | Hypusine. | Swiss-Prot 53.0 | 68 | N6-acetyllysine. | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr17 |
Promoter: 7150193 - 7152193 | Agilent_014791 |
chr17 |
Promoter: 7150193 - 7152193 | GSE27584 |
chr17 |
Promoter: 7150193 - 7152193 | Agilent_014791_44K |