Cell senescence gene database Home
Cell senescence database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

1736

Name

DKC1

Synonymous

dyskeratosis congenita 1, dyskerin;DKC1;dyskeratosis congenita 1, dyskerin

Definition

CBF5 homolog|H/ACA ribonucleoprotein complex subunit 4|nopp140-associated protein of 57 kDa|nucleolar protein NAP57|nucleolar protein family A member 4|snoRNP protein DKC1

Position

Xq28

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors   [Top]

Regulation From TransFac database

DKC1(h) --> dkc1(h) (expression).
dkc1(h) + EF1G(h) <==> dkc1(h):EF1G(h) (binding)
rps19(h) + dkc1(h) <==> rps19(h):dkc1(h) (binding)
rps19(h) + dkc1(h) <==> rps19(h):dkc1(h) (binding)
DKC1(h) --> dkc1(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

2N-acetylalanine.Swiss-Prot 53.0
21Phosphoserine.Swiss-Prot 53.0
451Phosphoserine.Swiss-Prot 53.0
453Phosphoserine.Swiss-Prot 53.0
455Phosphoserine.Swiss-Prot 53.0
458Phosphothreonine.Swiss-Prot 53.0
485Phosphoserine (By similarity).Swiss-Prot 53.0
494Phosphoserine.Swiss-Prot 53.0
513Phosphoserine.Swiss-Prot 53.0
493Phosphoserine15302935;17081983Phospho.ELM 6.0
512Phosphoserine15302935;17081983Phospho.ELM 6.0
450Phosphoserine16083285;17081983Phospho.ELM 6.0
452Phosphoserine16083285;17081983Phospho.ELM 6.0
454Phosphoserine16083285;17081983Phospho.ELM 6.0
20Phosphoserine16565220;17081983Phospho.ELM 6.0
457Phosphothreonine17081983Phospho.ELM 6.0
484Phosphoserine17081983Phospho.ELM 6.0

Methylation Profile   [Top]

Chromosome

Location

Source

chrX

Promoter: 153642844 - 153644844Agilent_014791

chrX

Promoter: 153642844 - 153644844GoldenGate_Methylation_Cancer_Panel_I

chrX

Promoter: 153642844 - 153644844GSE27584

chrX

Promoter: 153642844 - 153644844Agilent_014791_44K


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