Entrez Gene

Basic Information
Gene ID	11065
Name	UBE2C
Synonymous	ubiquitin-conjugating enzyme E2C;UBE2C;ubiquitin-conjugating enzyme E2C
Definition	cyclin-selective ubiquitin carrier protein\|mitotic-specific ubiquitin-conjugating enzyme\|ubiquitin-conjugating enzyme E2 C\|ubiquitin-protein ligase C
Position	20q13.12
Gene Type	protein-coding
Gene Regulation:	Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database

Regulation From TransFac database
Transcription Factors [Top]
E2-C(h) --/ cyclinA(h) (decrease of abundance)
E2-C(h) --> Cdc20(h):MAD2(h) (decrease of binding)
E2-C(h) + n ubiquitin(h) --> E2-C(h){ub}n (ubiquitination; automodification)
UBE2C(h) --> E2-C(h) (expression).
cyclinB(h) + n ubiquitin(b) --E1(h),E2-C(h),cyclosome(m){p}n--> cyclinB(h){ub(n)} (ubiquitination)
securin(fy) + n ubiquitin(b) --E1(m),E2-C(h),cyclosome(m):Cdc20(h){p}--> securin(fy){ub(n)} (ubiquitination)
cyclinB(h) + n ubiquitin(b) --E1(m),E2-C(h),cyclosome(m):Cdc20(h){p}--> cyclinB(h){ub(n)} (ubiquitination)
cyclinB(h) + n ubiquitin(b) --E1(m),E2-C(h),cyclosome(m):Fzr(h)--> cyclinB(h){ub(n)} (ubiquitination)
Skp2(h) + n ubiquitin(v.s.) --E1(v.s.),E2-C(h),cyclosome(x):Fzr(h)--> Skp2(h){ub(n)} (ubiquitination)
E1(h){ub} + E2-C(h) --> E1(h) + E2-C(h){ub} (ubiquitination; conjugation)
UBE2C(h) --> E2-C(h) (expression).
Aurora-B(h) + n ubiquitin(h) --E2-C(h),cyclosome(x):Fzr1(h)--> Aurora-B(h){ub(n)} (ubiquitination)
Aurora-B(h) + ubiquitin(h) --E2-C(h),cyclosome(x):Cdc20(h)--> Aurora-B(h){ub} (ubiquitination)
TPX2(h) + n ubiquitin(h) --E2-C(h),cyclosome(x):Fzr1(h)--> TPX2(h){ub}n (ubiquitination)

Post Transcriptional Modification [Top]
	There is no record for UBE2C

Transcription Factors [Top]