| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 1058 |
Name | CENPA |
Synonymous | centromere protein A;CENPA;centromere protein A |
Definition | centromere autoantigen A|centromere protein A, 17kDa|centromere-specific histone|histone H3-like centromeric protein A |
Position | 2p23.3 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | CENP-A(h) + ATP --Aurora-B(h)--> CENP-A(h){pS7} + ADP (phosphorylation) | Aurora-A(h) + CENP-A(h) <==> Aurora-A(h):CENP-A(h) (binding) | CENP-A(h) + ATP --Aurora-A(h)--> CENP-A(h){pS7} + ADP (phosphorylation) | CENPA(h) --> CENP-A(h) (expression). | CENPA(h) --> CENP-A(h) (expression). |
|---|
Post Transcriptional Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 7 | Phosphoserine (by STK6 and STK12). | Swiss-Prot 53.0 | 17 | Phosphoserine. | Swiss-Prot 53.0 | 19 | Phosphoserine. | Swiss-Prot 53.0 | 7 | Phosphoserine (Aurora A;Aur) | 11756469;14667408;15108802 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr2 |
Promoter: 26860886 - 26862886 | Agilent_014791 |
chr2 |
Promoter: 26860886 - 26862886 | GSE27584 |
chr2 |
Promoter: 26860887 - 26862887 | GSE27584 |
chr2 |
Promoter: 26860887 - 26862887 | Agilent_014791_44K |