Entrez Gene

Basic Information
Gene ID	8727
Name	CTNNAL1
Synonymous	catenin (cadherin-associated protein), alpha-like 1;CTNNAL1;catenin (cadherin-associated protein), alpha-like 1
Definition	alpha-catenin-related protein\|alpha-catulin\|alpha2-catulin\|catenin alpha-like protein 1
Position	9q31.2
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.924G>A; p.E308E; 9:108979458-108979458	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1161T>C; p.S387S; 9:108976989-108976989	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.304A>G; p.I102V; 9:108999094-108999094	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.948G>A; p.E316E; 9:108979434-108979434	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.868A>G; p.I290V; 9:108983177-108983177	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1159A>C; p.S387R; 9:108976991-108976991	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.262G>A; p.A88T; 9:108999136-108999136	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1672G>A; p.D558N; 9:108952452-108952452	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.753C>T; p.C251C; 9:108983292-108983292	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2092G>A; p.A698T; 9:108943008-108943008	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.255A>G; p.V85V; 9:108999143-108999143	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.687A>G; p.A229A; 9:108984389-108984389	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1859C>T; p.S620F; 9:108948211-108948211	skin; mucosal	malignant_melanoma	Substitution - Missense
c.648A>T; p.K216N; 9:108984428-108984428	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.166G>T; p.D56Y; 9:108999232-108999232	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.124C>G; p.L42V; 9:109013319-109013319	breast	carcinoma	Substitution - Missense
c.1561G>T; p.E521*; 9:108965408-108965408	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.994delT; p.F332fs*29; 9:108979388-108979388	prostate	carcinoma	Deletion - Frameshift
c.2158G>A; p.G720R; 9:108942816-108942816	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.878T>G; p.F293C; 9:108983167-108983167	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.416C>G; p.T139R; 9:108992735-108992735	urinary_tract; bladder	carcinoma	Substitution - Missense
c.2057T>A; p.V686D; 9:108943043-108943043	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.5C>A; p.A2D; 9:109013438-109013438	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.1364G>A; p.R455Q; 9:108970478-108970478	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1303G>C; p.E435Q; 9:108972719-108972719	urinary_tract; bladder	carcinoma	Substitution - Missense
c.139C>T; p.Q47*; 9:109013304-109013304	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1364G>A; p.R455Q; 9:108970478-108970478	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1303G>C; p.E435Q; 9:108972719-108972719	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.431C>A; p.A144D; 9:108992720-108992720	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.356A>C; p.D119A; 9:108992795-108992795	ovary	other; neoplasm	Substitution - Missense
c.975C>G; p.I325M; 9:108979407-108979407	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1951G>A; p.D651N; 9:108943807-108943807	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2147T>G; p.M716R; 9:108942827-108942827	bone; extraskeletal	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.526G>A; p.A176T; 9:108990839-108990839	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1941+1G>A; p.?; 9:108943961-108943961	skin; head_neck	carcinoma; squamous_cell_carcinoma	Unknown
c.1401T>C; p.C467C; 9:108970441-108970441	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.431C>G; p.A144G; 9:108992720-108992720	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1006G>T; p.A336S; 9:108979376-108979376	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1525G>T; p.E509*; 9:108965444-108965444	skin	malignant_melanoma	Substitution - Nonsense
c.1265A>C; p.K422T; 9:108972757-108972757	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.265A>G; p.I89V; 9:108999133-108999133	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.1392A>T; p.E464D; 9:108970450-108970450	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.398C>G; p.T133R; 9:108992753-108992753	liver	carcinoma	Substitution - Missense
c.398C>G; p.T133R; 9:108992753-108992753	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.1583G>A; p.G528E; 9:108965386-108965386	breast	carcinoma	Substitution - Missense
c.1694T>C; p.I565T; 9:108952350-108952350	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1838G>A; p.G613E; 9:108948232-108948232	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.1317A>T; p.K439N; 9:108972705-108972705	breast	carcinoma	Substitution - Missense
c.983G>A; p.R328H; 9:108979399-108979399	breast	carcinoma	Substitution - Missense
c.983G>A; p.R328H; 9:108979399-108979399	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.791G>A; p.R264H; 9:108983254-108983254	urinary_tract; bladder	carcinoma	Substitution - Missense
c.791G>A; p.R264H; 9:108983254-108983254	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.245T>G; p.F82C; 9:108999153-108999153	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.150G>A; p.T50T; 9:108999248-108999248	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.150G>A; p.T50T; 9:108999248-108999248	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.691C>T; p.L231F; 9:108984385-108984385	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1942-2A>T; p.?; 9:108943818-108943818	thyroid	carcinoma	Unknown
c.2087T>C; p.M696T; 9:108943013-108943013	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1608C>A; p.Y536*; 9:108955811-108955811	prostate	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1165A>G; p.S389G; 9:108976985-108976985	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1608C>A; p.Y536*; 9:108955811-108955811	prostate	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1303G>A; p.E435K; 9:108972719-108972719	skin	malignant_melanoma	Substitution - Missense
c.1209G>A; p.Q403Q; 9:108972813-108972813	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.924G>T; p.E308D; 9:108979458-108979458	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1794G>A; p.R598R; 9:108952250-108952250	skin	malignant_melanoma	Substitution - coding silent
c.1483A>T; p.K495*; 9:108965486-108965486	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.2085C>T; p.S695S; 9:108943015-108943015	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1329G>A; p.Q443Q; 9:108972693-108972693	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2198A>C; p.K733T; 9:108942776-108942776	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1579G>C; p.E527Q; 9:108965390-108965390	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.1579G>C; p.E527Q; 9:108965390-108965390	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.857A>T; p.D286V; 9:108983188-108983188	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.919C>T; p.R307W; 9:108979463-108979463	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.919C>T; p.R307W; 9:108979463-108979463	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.919C>T; p.R307W; 9:108979463-108979463	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.757T>A; p.S253T; 9:108983288-108983288	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.1075C>T; p.Q359*; 9:108979307-108979307	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.886A>T; p.I296F; 9:108983159-108983159	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1428G>T; p.V476V; 9:108970414-108970414	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.272A>C; p.N91T; 9:108999126-108999126	bone; extraskeletal	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.1273G>A; p.G425R; 9:108972749-108972749	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.177A>C; p.K59N; 9:108999221-108999221	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.423G>A; p.V141V; 9:108992728-108992728	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.423G>A; p.V141V; 9:108992728-108992728	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.266T>G; p.I89R; 9:108999132-108999132	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.1203G>A; p.A401A; 9:108972819-108972819	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1817C>T; p.S606F; 9:108952227-108952227	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1778T>G; p.I593S; 9:108952266-108952266	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1629+7A>G; p.?; 9:108955783-108955783	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Unknown
c.1186G>T; p.E396*; 9:108976964-108976964	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1030G>T; p.E344*; 9:108979352-108979352	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1786T>G; p.Y596D; 9:108952258-108952258	liver	carcinoma	Substitution - Missense
c.1376G>A; p.G459E; 9:108970466-108970466	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.840A>G; p.K280K; 9:108983205-108983205	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1202C>A; p.A401E; 9:108972820-108972820	breast	carcinoma	Substitution - Missense
c.1202C>A; p.A401E; 9:108972820-108972820	breast	carcinoma	Substitution - Missense

COSMIC somatic mutation [Top]