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Cell senescence database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

8726

Name

EED

Synonymous

embryonic ectoderm development;EED;embryonic ectoderm development

Definition

WD protein associating with integrin cytoplasmic tails 1|polycomb protein EED

Position

11q14.2-q22.3

Gene Type

protein-coding

COSMIC somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.552G>T; p.K184N; 11:86256512-86256512

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.966+3A>G; p.?; 11:86268564-86268564

 livercarcinomaUnknown

c.594C>T; p.F198F; 11:86257556-86257556

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.806G>T; p.R269I; 11:86266162-86266162

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.806G>T; p.R269I; 11:86266162-86266162

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.508G>A; p.G170S; 11:86256468-86256468

 skinmalignant_melanomaSubstitution - Missense

c.330A>G; p.P110P; 11:86252210-86252210

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.673C>G; p.L225V; 11:86264210-86264210

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.470A>G; p.N157S; 11:86256430-86256430

 livercarcinomaSubstitution - Missense

c.1172T>C; p.L391S; 11:86277964-86277964

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1064G>A; p.R355Q; 11:86277077-86277077

 breastcarcinomaSubstitution - Missense

c.560T>G; p.V187G; 11:86257522-86257522

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.758C>T; p.S253F; 11:86266114-86266114

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.120C>T; p.D40D; 11:86250301-86250301

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.188C>A; p.P63H; 11:86250369-86250369

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1119G>A; p.W373*; 11:86277132-86277132

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.587T>A; p.L196Q; 11:86257549-86257549

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.587T>A; p.L196Q; 11:86257549-86257549

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.587T>A; p.L196Q; 11:86257549-86257549

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.142A>G; p.T48A; 11:86250323-86250323

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.424G>A; p.D142N; 11:86255285-86255285

 breastcarcinomaSubstitution - Missense

c.674T>C; p.L225P; 11:86264211-86264211

 skinmalignant_melanomaSubstitution - Missense

c.33G>A; p.A11A; 11:86245262-86245262

 ovarycarcinoma; serous_carcinomaSubstitution - coding silent

c.955A>C; p.I319L; 11:86268550-86268550

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.376T>C; p.C126R; 11:86255237-86255237

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.904A>G; p.R302G; 11:86268499-86268499

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; myelofibrosisSubstitution - Missense

c.510C>T; p.G170G; 11:86256470-86256470

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.350G>T; p.G117V; 11:86252230-86252230

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1321C>T; p.R441*; 11:86278520-86278520

 skinmalignant_melanomaSubstitution - Nonsense

c.1116C>A; p.F372L; 11:86277129-86277129

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1321C>T; p.R441*; 11:86278520-86278520

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.964A>G; p.K322E; 11:86268559-86268559

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.751A>G; p.I251V; 11:86266107-86266107

 thyroidcarcinomaSubstitution - Missense

c.695T>C; p.V232A; 11:86264232-86264232

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.690A>T; p.G230G; 11:86264227-86264227

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.121G>A; p.A41T; 11:86250302-86250302

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.274C>T; p.H92Y; 11:86252154-86252154

 skinmalignant_melanomaSubstitution - Missense

c.213delA; p.K72fs*14; 11:86250394-86250394

 large_intestinecarcinoma; adenocarcinomaDeletion - Frameshift

c.213delA; p.K72fs*14; 11:86250394-86250394

 large_intestinecarcinoma; adenocarcinomaDeletion - Frameshift

c.778C>T; p.L260F; 11:86266134-86266134

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.180A>G; p.P60P; 11:86250361-86250361

 ovarycarcinoma; serous_carcinomaSubstitution - coding silent

c.903C>T; p.T301T; 11:86268498-86268498

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.397C>T; p.R133W; 11:86255258-86255258

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.619C>T; p.L207L; 11:86257581-86257581

 breastcarcinomaSubstitution - coding silent

c.1054A>G; p.I352V; 11:86277067-86277067

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.114T>A; p.N38K; 11:86245343-86245343

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - Missense

c.104G>A; p.G35E; 11:86245333-86245333

 thyroidcarcinomaSubstitution - Missense

c.413A>T; p.Y138F; 11:86255274-86255274

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.413A>T; p.Y138F; 11:86255274-86255274

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1088T>C; p.I363T; 11:86277101-86277101

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.509G>T; p.G170V; 11:86256469-86256469

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.319G>A; p.E107K; 11:86252199-86252199

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1199+10T>C; p.?; 11:86278001-86278001

 stomachcarcinoma; adenocarcinomaUnknown

c.813G>T; p.M271I; 11:86266169-86266169

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.788G>T; p.W263L; 11:86266144-86266144

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.948C>T; p.G316G; 11:86268543-86268543

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.607C>A; p.P203T; 11:86257569-86257569

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.28C>T; p.P10S; 11:86245257-86245257

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - Missense

c.484C>T; p.L162L; 11:86256444-86256444

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - coding silent

c.484C>T; p.L162L; 11:86256444-86256444

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.1110G>A; p.M370I; 11:86277123-86277123

 skinmalignant_melanomaSubstitution - Missense

c.230A>G; p.K77R; 11:86250411-86250411

 breastcarcinomaSubstitution - Missense

c.949G>A; p.D317N; 11:86268544-86268544

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.949G>A; p.D317N; 11:86268544-86268544

 pancreascarcinoid-endocrine_tumour; islet_cellSubstitution - Missense

c.230A>G; p.K77R; 11:86250411-86250411

 breastcarcinomaSubstitution - Missense

c.1077C>T; p.S359S; 11:86277090-86277090

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.288G>T; p.L96F; 11:86252168-86252168

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1322G>A; p.R441Q; 11:86278521-86278521

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.224C>G; p.S75*; 11:86250405-86250405

 urinary_tract; bladdercarcinomaSubstitution - Nonsense

c.1241G>C; p.R414P; 11:86278440-86278440

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.752T>C; p.I251T; 11:86266108-86266108

 breastcarcinomaSubstitution - Missense

c.337T>C; p.F113L; 11:86252217-86252217

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1129C>A; p.L377I; 11:86277921-86277921

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.137G>C; p.S46T; 11:86250318-86250318

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.224C>A; p.S75*; 11:86250405-86250405

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Nonsense

c.624A>C; p.S208S; 11:86257586-86257586

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.482C>T; p.P161L; 11:86256442-86256442

 skinmalignant_melanomaSubstitution - Missense

c.1231G>C; p.A411P; 11:86278430-86278430

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.776C>T; p.S259F; 11:86266132-86266132

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; acute_lymphoblastic_T_cell_leukaemiaSubstitution - Missense

c.776C>T; p.S259F; 11:86266132-86266132

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; acute_lymphoblastic_T_cell_leukaemiaSubstitution - Missense

c.27G>A; p.A9A; 11:86245256-86245256

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1118G>A; p.W373*; 11:86277131-86277131

 oesophaguscarcinoma; adenocarcinomaSubstitution - Nonsense

c.861-3C>T; p.?; 11:86268453-86268453

 skin; head_neckcarcinoma; squamous_cell_carcinomaUnknown

c.535A>G; p.T179A; 11:86256495-86256495

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

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