Entrez Gene

Basic Information
Gene ID	8635
Name	RNASET2
Synonymous	ribonuclease T2;RNASET2;ribonuclease T2
Definition	ribonuclease 6
Position	6q27
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.614A>C; p.K205T; 6:166929745-166929745	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.447-1G>A; p.?; 6:166934137-166934137	large_intestine; caecum	carcinoma; adenocarcinoma	Unknown
c.175C>T; p.P59S; 6:166948598-166948598	skin	malignant_melanoma	Substitution - Missense
c.649G>A; p.G217R; 6:166929710-166929710	skin	malignant_melanoma	Substitution - Missense
c.705_718del14; p.R236fs*2; 6:166929641-166929654	stomach	carcinoma; mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	Deletion - Frameshift
c.621C>T; p.D207D; 6:166929738-166929738	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.770G>C; p.*257S; 6:166929589-166929589	lung	carcinoma; adenocarcinoma	Nonstop extension
c.380C>T; p.A127V; 6:166938961-166938961	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.380C>T; p.A127V; 6:166938961-166938961	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.255G>T; p.E85D; 6:166946688-166946688	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.747C>T; p.P249P; 6:166929612-166929612	skin	malignant_melanoma	Substitution - coding silent
c.446+8C>T; p.?; 6:166938887-166938887	endometrium	carcinoma; endometrioid_carcinoma	Unknown
c.598G>A; p.E200K; 6:166929761-166929761	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.402C>T; p.Y134Y; 6:166938939-166938939	skin	malignant_melanoma	Substitution - coding silent
c.641C>T; p.T214I; 6:166929718-166929718	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.390C>T; p.S130S; 6:166938951-166938951	skin	malignant_melanoma	Substitution - coding silent
c.593A>G; p.Q198R; 6:166929766-166929766	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.518C>T; p.A173V; 6:166931093-166931093	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.567+1G>T; p.?; 6:166931043-166931043	lung	carcinoma; adenocarcinoma	Unknown
c.21C>T; p.R7R; 6:166956162-166956162	breast	carcinoma	Substitution - coding silent
c.599A>C; p.E200A; 6:166929760-166929760	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.204G>A; p.W68*; 6:166946739-166946739	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Nonsense
c.145G>A; p.E49K; 6:166952490-166952490	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.145G>A; p.E49K; 6:166952490-166952490	stomach	adenocarcinoma	Substitution - Missense
c.517G>A; p.A173T; 6:166931094-166931094	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.364G>A; p.A122T; 6:166938977-166938977	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.387C>A; p.N129K; 6:166938954-166938954	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; hairy_cell_leukaemia	Substitution - Missense
c.707G>A; p.R236Q; 6:166929652-166929652	meninges	meningioma; secretory	Substitution - Missense
c.338A>T; p.H113L; 6:166939003-166939003	bone; fibula	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.231A>T; p.R77S; 6:166946712-166946712	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.231A>T; p.R77S; 6:166946712-166946712	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.450G>A; p.V150V; 6:166934133-166934133	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.663C>T; p.S221S; 6:166929696-166929696	skin	malignant_melanoma	Substitution - coding silent
c.706C>T; p.R236W; 6:166929653-166929653	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.706C>T; p.R236W; 6:166929653-166929653	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.516T>C; p.L172L; 6:166931095-166931095	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.372G>A; p.Q124Q; 6:166938969-166938969	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.97G>A; p.E33K; 6:166952538-166952538	breast	carcinoma	Substitution - Missense
c.482A>G; p.N161S; 6:166934101-166934101	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.418G>A; p.E140K; 6:166938923-166938923	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.508G>T; p.D170Y; 6:166931103-166931103	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense

COSMIC somatic mutation [Top]