Cell senescence gene database Home
Cell senescence database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

84868

Name

HAVCR2

Synonymous

hepatitis A virus cellular receptor 2;HAVCR2;hepatitis A virus cellular receptor 2

Definition

T cell immunoglobulin mucin 3|T cell immunoglobulin mucin-3|T-cell immunoglobulin and mucin domain-containing protein 3|T-cell immunoglobulin mucin family member 3|T-cell immunoglobulin mucin receptor 3|T-cell membrane protein 3|kidney injury molecule-3

Position

5q33.3

Gene Type

protein-coding

COSMIC somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.221A>G; p.D74G; 5:157106800-157106800

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.661G>T; p.A221S; 5:157095321-157095321

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.556T>A; p.S186T; 5:157095426-157095426

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.166G>A; p.G56R; 5:157106855-157106855

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.649C>G; p.L217V; 5:157095333-157095333

 oesophaguscarcinomaSubstitution - Missense

c.328T>A; p.C110S; 5:157106693-157106693

 skin; mucosalmalignant_melanomaSubstitution - Missense

c.576A>T; p.L192F; 5:157095406-157095406

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.41T>C; p.L14P; 5:157108943-157108943

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.186A>G; p.E62E; 5:157106835-157106835

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.861G>C; p.R287S; 5:157087147-157087147

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.271G>A; p.G91R; 5:157106750-157106750

 skin; facecarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.550C>T; p.R184W; 5:157095432-157095432

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.766G>A; p.E256K; 5:157087242-157087242

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.475C>A; p.P159T; 5:157104669-157104669

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.766G>A; p.E256K; 5:157087242-157087242

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - Missense

c.257G>T; p.G86V; 5:157106764-157106764

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.168A>G; p.G56G; 5:157106853-157106853

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.16C>T; p.P6S; 5:157108968-157108968

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.425G>A; p.R142K; 5:157104719-157104719

 skinmalignant_melanomaSubstitution - Missense

c.372C>T; p.N124N; 5:157106649-157106649

 prostatecarcinomaSubstitution - coding silent

c.290T>C; p.I97T; 5:157106731-157106731

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.130G>A; p.A44T; 5:157106891-157106891

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.175C>T; p.P59S; 5:157106846-157106846

 skinmalignant_melanomaSubstitution - Missense

c.130G>A; p.A44T; 5:157106891-157106891

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.489G>T; p.Q163H; 5:157098891-157098891

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.266G>A; p.R89H; 5:157106755-157106755

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.745G>T; p.G249*; 5:157087263-157087263

 prostatecarcinoma; adenocarcinomaSubstitution - Nonsense

c.60G>A; p.R20R; 5:157106961-157106961

 skinmalignant_melanomaSubstitution - coding silent

c.867A>G; p.Q289Q; 5:157087141-157087141

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.36G>T; p.L12L; 5:157108948-157108948

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.776G>T; p.R259L; 5:157087232-157087232

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.705G>A; p.Q235Q; 5:157088949-157088949

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.83C>T; p.A28V; 5:157106938-157106938

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.83C>T; p.A28V; 5:157106938-157106938

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.478G>A; p.A160T; 5:157104666-157104666

 skinmalignant_melanomaSubstitution - Missense

c.195C>T; p.N65N; 5:157106826-157106826

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.801T>C; p.I267I; 5:157087207-157087207

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.45_47delGCT; p.L18delL; 5:157108937-157108939

 large_intestine; caecumcarcinoma; adenocarcinomaDeletion - In frame

c.427G>T; p.D143Y; 5:157104717-157104717

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.144C>A; p.L48L; 5:157106877-157106877

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.594C>T; p.T198T; 5:157095388-157095388

 bone; vertebraeEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - coding silent

c.71T>G; p.V24G; 5:157106950-157106950

 breastcarcinomaSubstitution - Missense

c.276delT; p.D92fs*4; 5:157106745-157106745

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.368T>G; p.F123C; 5:157106653-157106653

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.128C>T; p.A43V; 5:157106893-157106893

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.584C>G; p.S195C; 5:157095398-157095398

 cervixcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.45G>A; p.L15L; 5:157108939-157108939

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.321C>A; p.I107I; 5:157106700-157106700

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.206G>A; p.R69K; 5:157106815-157106815

 skinmalignant_melanomaSubstitution - Missense

c.775C>T; p.R259C; 5:157087233-157087233

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.779C>A; p.S260*; 5:157087229-157087229

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Nonsense

c.58A>C; p.R20R; 5:157108926-157108926

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.245A>G; p.Y82C; 5:157106776-157106776

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.337C>A; p.Q113K; 5:157106684-157106684

 skinmalignant_melanomaSubstitution - Missense

c.449G>T; p.R150M; 5:157104695-157104695

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.449G>T; p.R150M; 5:157104695-157104695

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.593C>T; p.T198I; 5:157095389-157095389

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; acute_lymphoblastic_leukaemiaSubstitution - Missense

c.124C>T; p.P42S; 5:157106897-157106897

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.838T>C; p.Y280H; 5:157087170-157087170

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.220G>T; p.D74Y; 5:157106801-157106801

 breastcarcinomaSubstitution - Missense

c.137G>A; p.G46E; 5:157106884-157106884

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.384C>A; p.V128V; 5:157106637-157106637

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.176C>T; p.P59L; 5:157106845-157106845

 skinmalignant_melanomaSubstitution - Missense

c.784G>A; p.E262K; 5:157087224-157087224

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.825G>T; p.E275D; 5:157087183-157087183

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.261T>G; p.D87E; 5:157106760-157106760

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.136G>T; p.G46W; 5:157106885-157106885

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.475_476CC>TT; p.P159L; 5:157104668-157104669

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.740C>T; p.P247L; 5:157087268-157087268

 skinmalignant_melanomaSubstitution - Missense

c.661G>A; p.A221T; 5:157095321-157095321

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.343C>G; p.P115A; 5:157106678-157106678

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.90C>T; p.V30V; 5:157106931-157106931

 prostatecarcinomaSubstitution - coding silent

c.615C>T; p.I205I; 5:157095367-157095367

 skinmalignant_melanomaSubstitution - coding silent

c.739C>T; p.P247S; 5:157087269-157087269

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.615C>T; p.I205I; 5:157095367-157095367

 upper_aerodigestive_tract; pharynxcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.683C>A; p.S228Y; 5:157088971-157088971

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.381G>T; p.L127F; 5:157106640-157106640

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.893T>A; p.F298Y; 5:157087115-157087115

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.722C>T; p.S241F; 5:157087286-157087286

 skinmalignant_melanomaSubstitution - Missense

c.722C>T; p.S241F; 5:157087286-157087286

 skinmalignant_melanomaSubstitution - Missense

c.253A>C; p.N85H; 5:157106768-157106768

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.253A>C; p.N85H; 5:157106768-157106768

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.153C>T; p.V51V; 5:157106868-157106868

 skinmalignant_melanomaSubstitution - coding silent

c.890G>A; p.R297H; 5:157087118-157087118

 central_nervous_system; brainprimitive_neuroectodermal_tumour-medulloblastomaSubstitution - Missense

c.677-4C>A; p.?; 5:157088981-157088981

 livercarcinomaUnknown

c.677-4C>A; p.?; 5:157088981-157088981

 livercarcinomaUnknown

c.63C>A; p.S21S; 5:157106958-157106958

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.414G>T; p.P138P; 5:157104730-157104730

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.354G>A; p.M118I; 5:157106667-157106667

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.102C>T; p.A34A; 5:157106919-157106919

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.426A>G; p.R142R; 5:157104718-157104718

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.102delC; p.Y35fs*41; 5:157106919-157106919

 large_intestine; caecumcarcinoma; adenocarcinomaDeletion - Frameshift

c.660C>T; p.G220G; 5:157095322-157095322

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.660C>T; p.G220G; 5:157095322-157095322

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.578G>A; p.R193Q; 5:157095404-157095404

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.231T>C; p.Y77Y; 5:157106790-157106790

 livercarcinomaSubstitution - coding silent

c.231T>C; p.Y77Y; 5:157106790-157106790

 livercarcinoma; hepatocellular_carcinomaSubstitution - coding silent

c.294G>T; p.E98D; 5:157106727-157106727

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.223G>T; p.V75L; 5:157106798-157106798

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.265C>T; p.R89C; 5:157106756-157106756

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.265C>T; p.R89C; 5:157106756-157106756

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.464G>T; p.R155M; 5:157104680-157104680

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

')