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Cell senescence database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

84733

Name

CBX2

Synonymous

chromobox homolog 2;CBX2;chromobox homolog 2

Definition

Pc class homolog|cell division cycle associated 6|chromobox homolog 2 (Pc class homolog, Drosophila)|chromobox protein homolog 2|modifier 3

Position

17q25.3

Gene Type

protein-coding

COSMIC somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.1413C>T; p.P471P; 17:79784856-79784856

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.1402G>A; p.D468N; 17:79784845-79784845

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.270C>T; p.S90S; 17:79781783-79781783

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.399T>A; p.G133G; 17:79783842-79783842

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.940G>A; p.G314S; 17:79784383-79784383

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.764C>T; p.S255F; 17:79784207-79784207

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.764C>T; p.S255F; 17:79784207-79784207

 large_intestine; coloncarcinomaSubstitution - Missense

c.334T>C; p.S112P; 17:79783777-79783777

 thyroidother; neoplasmSubstitution - Missense

c.1021C>T; p.P341S; 17:79784464-79784464

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1570G>C; p.V524L; 17:79785013-79785013

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1038A>T; p.A346A; 17:79784481-79784481

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.491G>T; p.R164L; 17:79783934-79783934

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1057C>A; p.L353I; 17:79784500-79784500

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1386G>A; p.E462E; 17:79784829-79784829

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.410G>A; p.R137H; 17:79783853-79783853

 livercarcinomaSubstitution - Missense

c.410G>A; p.R137H; 17:79783853-79783853

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.410G>A; p.R137H; 17:79783853-79783853

 livercarcinomaSubstitution - Missense

c.301C>T; p.P101S; 17:79783744-79783744

 skinmalignant_melanomaSubstitution - Missense

c.881C>T; p.T294M; 17:79784324-79784324

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.870G>A; p.L290L; 17:79784313-79784313

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.332C>T; p.S111F; 17:79783775-79783775

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1418C>T; p.S473F; 17:79784861-79784861

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - Missense

c.840C>T; p.A280A; 17:79784283-79784283

 autonomic_ganglianeuroblastomaSubstitution - coding silent

c.925_926CC>TT; p.P309L; 17:79784368-79784369

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1441C>T; p.Q481*; 17:79784884-79784884

 lungcarcinoma; small_cell_carcinomaSubstitution - Nonsense

c.453G>T; p.V151V; 17:79783896-79783896

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1449G>A; p.P483P; 17:79784892-79784892

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.409C>T; p.R137C; 17:79783852-79783852

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.409C>T; p.R137C; 17:79783852-79783852

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1542C>T; p.T514T; 17:79784985-79784985

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.939C>T; p.S313S; 17:79784382-79784382

 breastcarcinomaSubstitution - coding silent

c.1110C>T; p.L370L; 17:79784553-79784553

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1458C>T; p.S486S; 17:79784901-79784901

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.417_418CC>TT; p.H140Y; 17:79783860-79783861

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.982C>T; p.P328S; 17:79784425-79784425

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1459G>A; p.V487I; 17:79784902-79784902

 pancreascarcinomaSubstitution - Missense

c.336C>A; p.S112S; 17:79783779-79783779

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.463G>A; p.E155K; 17:79783906-79783906

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.746G>A; p.G249D; 17:79784189-79784189

 thyroidother; neoplasmSubstitution - Missense

c.522G>C; p.K174N; 17:79783965-79783965

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.615C>T; p.S205S; 17:79784058-79784058

 stomachadenocarcinomaSubstitution - coding silent

c.1307delC; p.S438fs*21; 17:79784750-79784750

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.935C>T; p.P312L; 17:79784378-79784378

 skinmalignant_melanomaSubstitution - Missense

c.1242G>A; p.L414L; 17:79784685-79784685

 breastcarcinomaSubstitution - coding silent

c.1242G>A; p.L414L; 17:79784685-79784685

 breastcarcinomaSubstitution - coding silent

c.1414G>A; p.D472N; 17:79784857-79784857

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.1569C>T; p.S523S; 17:79785012-79785012

 pancreascarcinomaSubstitution - coding silent

c.1569C>T; p.S523S; 17:79785012-79785012

 breastcarcinomaSubstitution - coding silent

c.1371G>A; p.E457E; 17:79784814-79784814

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.1474G>T; p.D492Y; 17:79784917-79784917

 lung; right_lower_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.1219G>A; p.D407N; 17:79784662-79784662

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.1219G>A; p.D407N; 17:79784662-79784662

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.116+5G>A; p.?; 17:79778432-79778432

 pancreascarcinomaUnknown

c.496C>T; p.R166*; 17:79783939-79783939

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Nonsense

c.853G>A; p.G285S; 17:79784296-79784296

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.862C>T; p.L288L; 17:79784305-79784305

 breastcarcinomaSubstitution - coding silent

c.778A>G; p.M260V; 17:79784221-79784221

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.236G>C; p.R79P; 17:79781749-79781749

 livercarcinomaSubstitution - Missense

c.236G>C; p.R79P; 17:79781749-79781749

 livercarcinomaSubstitution - Missense

c.1425G>A; p.S475S; 17:79784868-79784868

 bone; femurEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - coding silent

c.1567A>T; p.S523C; 17:79785010-79785010

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - Missense

c.1567A>T; p.S523C; 17:79785010-79785010

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.552G>T; p.K184N; 17:79783995-79783995

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.441C>T; p.A147A; 17:79783884-79783884

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1447C>T; p.P483S; 17:79784890-79784890

 skin; mucosalmalignant_melanomaSubstitution - Missense

c.1397G>A; p.S466N; 17:79784840-79784840

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1098C>T; p.P366P; 17:79784541-79784541

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1122C>T; p.H374H; 17:79784565-79784565

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.1032G>C; p.Q344H; 17:79784475-79784475

 autonomic_ganglianeuroblastomaSubstitution - Missense

c.855C>T; p.G285G; 17:79784298-79784298

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1489C>A; p.R497S; 17:79784932-79784932

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.1519G>A; p.D507N; 17:79784962-79784962

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.397G>A; p.G133S; 17:79783840-79783840

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1420G>A; p.A474T; 17:79784863-79784863

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.795G>T; p.Q265H; 17:79784238-79784238

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.602C>T; p.P201L; 17:79784045-79784045

 skinmalignant_melanomaSubstitution - Missense

c.1170G>A; p.K390K; 17:79784613-79784613

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1401G>A; p.S467S; 17:79784844-79784844

 lung; right_lower_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.797G>A; p.S266N; 17:79784240-79784240

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.302C>T; p.P101L; 17:79783745-79783745

 skin; acralmalignant_melanomaSubstitution - Missense

c.254C>T; p.A85V; 17:79781767-79781767

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.275G>A; p.R92H; 17:79781788-79781788

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.411C>T; p.R137R; 17:79783854-79783854

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1213_1214CC>TT; p.P405F; 17:79784656-79784657

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.579G>T; p.L193L; 17:79784022-79784022

 lung; right_lower_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.1232G>T; p.S411I; 17:79784675-79784675

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.504C>T; p.P168P; 17:79783947-79783947

 lung; right_lower_lobecarcinoma; adenocarcinomaSubstitution - coding silent

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