Entrez Gene

Basic Information
Gene ID	8364
Name	HIST1H4C
Synonymous	histone cluster 1, H4c;HIST1H4C;histone cluster 1, H4c
Definition	H4 histone family, member G\|histone 1, H4c\|histone H4
Position	6p22.1
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.46G>A; p.A16T; 6:26103993-26103993	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.203G>C; p.R68P; 6:26104150-26104150	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.242C>T; p.T81I; 6:26104189-26104189	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.54C>G; p.R18R; 6:26104001-26104001	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma; medullomyoblastoma	Substitution - coding silent
c.54C>G; p.R18R; 6:26104001-26104001	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - coding silent
c.210C>T; p.A70A; 6:26104157-26104157	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.124G>C; p.G42R; 6:26104071-26104071	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.162G>A; p.E54E; 6:26104109-26104109	pancreas	carcinoma	Substitution - coding silent
c.273A>G; p.L91L; 6:26104220-26104220	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.152T>C; p.I51T; 6:26104099-26104099	central_nervous_system; brain	glioma	Substitution - Missense
c.263T>C; p.V88A; 6:26104210-26104210	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.263T>C; p.V88A; 6:26104210-26104210	urinary_tract; bladder	carcinoma	Substitution - Missense
c.270C>A; p.A90A; 6:26104217-26104217	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - coding silent
c.153C>T; p.I51I; 6:26104100-26104100	oesophagus	carcinoma	Substitution - coding silent
c.29G>C; p.G10A; 6:26103976-26103976	pancreas	carcinoma	Substitution - Missense
c.54C>T; p.R18R; 6:26104001-26104001	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.106C>A; p.R36S; 6:26104053-26104053	liver	carcinoma	Substitution - Missense
c.106C>A; p.R36S; 6:26104053-26104053	liver	carcinoma	Substitution - Missense
c.115G>T; p.A39S; 6:26104062-26104062	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.30C>G; p.G10G; 6:26103977-26103977	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - coding silent
c.143C>T; p.S48F; 6:26104090-26104090	skin	malignant_melanoma	Substitution - Missense
c.166C>G; p.R56G; 6:26104113-26104113	skin	malignant_melanoma	Substitution - Missense
c.192G>A; p.E64E; 6:26104139-26104139	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.105T>C; p.I35I; 6:26104052-26104052	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.208G>A; p.A70T; 6:26104155-26104155	skin; ear	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.294G>A; p.L98L; 6:26104241-26104241	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - coding silent
c.55C>T; p.H19Y; 6:26104002-26104002	skin	malignant_melanoma	Substitution - Missense
c.116C>T; p.A39V; 6:26104063-26104063	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.4T>G; p.S2A; 6:26103951-26103951	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; plasma_cell_myeloma	Substitution - Missense
c.132C>T; p.V44V; 6:26104079-26104079	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.144C>T; p.S48S; 6:26104091-26104091	skin	malignant_melanoma	Substitution - coding silent
c.199A>G; p.I67V; 6:26104146-26104146	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.279T>C; p.R93R; 6:26104226-26104226	oesophagus	carcinoma	Substitution - coding silent

COSMIC somatic mutation [Top]