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Cell senescence database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

8358

Name

HIST1H3B

Synonymous

histone cluster 1, H3b;HIST1H3B;histone cluster 1, H3b

Definition

H3 histone family, member L|histone 1, H3b|histone H3.1|histone H3/l

Position

6p22.2

Gene Type

protein-coding

COSMIC somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.323C>T; p.T108I; 6:26031738-26031738

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.143C>T; p.A48V; 6:26031918-26031918

 skinmalignant_melanomaSubstitution - Missense

c.218G>C; p.R73P; 6:26031843-26031843

 breastcarcinomaSubstitution - Missense

c.219A>G; p.R73R; 6:26031842-26031842

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.119A>C; p.H40P; 6:26031942-26031942

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.139G>T; p.V47L; 6:26031922-26031922

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.228C>T; p.A76A; 6:26031833-26031833

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.352G>A; p.V118M; 6:26031709-26031709

 breastcarcinomaSubstitution - Missense

c.241A>G; p.T81A; 6:26031820-26031820

 oesophagus; lower_thirdcarcinoma; adenocarcinomaSubstitution - Missense

c.104G>A; p.G35D; 6:26031957-26031957

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.255C>T; p.F85F; 6:26031806-26031806

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.114G>C; p.K38N; 6:26031947-26031947

 central_nervous_system; braingliomaSubstitution - Missense

c.292G>T; p.E98*; 6:26031769-26031769

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Nonsense

c.379C>T; p.L127F; 6:26031682-26031682

 haematopoietic_and_lymphoid_tissue; lymph_nodelymphoid_neoplasm; diffuse_large_B_cell_lymphomaSubstitution - Missense

c.151G>C; p.E51Q; 6:26031910-26031910

 lung; right_lower_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.151G>C; p.E51Q; 6:26031910-26031910

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.394C>G; p.R132G; 6:26031667-26031667

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.239_411del173; p.?; 6:26031546-26031822

 stomachcarcinoma; intestinal_adenocarcinomaUnknown

c.283G>T; p.E95*; 6:26031778-26031778

 breastcarcinomaSubstitution - Nonsense

c.83A>C; p.K28T; 6:26031978-26031978

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.310C>T; p.L104F; 6:26031751-26031751

 breastcarcinomaSubstitution - Missense

c.237C>A; p.F79L; 6:26031824-26031824

 breastcarcinomaSubstitution - Missense

c.270G>A; p.V90V; 6:26031791-26031791

 lung; middle_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.274G>A; p.A92T; 6:26031787-26031787

 skin; facecarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.95C>A; p.A32D; 6:26031966-26031966

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.240G>C; p.K80N; 6:26031821-26031821

 breastcarcinomaSubstitution - Missense

c.350G>C; p.R117P; 6:26031711-26031711

 cervixcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.292G>A; p.E98K; 6:26031769-26031769

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.292G>A; p.E98K; 6:26031769-26031769

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.220G>A; p.E74K; 6:26031841-26031841

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.220G>A; p.E74K; 6:26031841-26031841

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.220G>A; p.E74K; 6:26031841-26031841

 breastcarcinomaSubstitution - Missense

c.220G>A; p.E74K; 6:26031841-26031841

 breastcarcinomaSubstitution - Missense

c.220G>A; p.E74K; 6:26031841-26031841

 skinmalignant_melanomaSubstitution - Missense

c.322A>G; p.T108A; 6:26031739-26031739

 breastcarcinomaSubstitution - Missense

c.229C>T; p.Q77*; 6:26031832-26031832

 skinmalignant_melanomaSubstitution - Nonsense

c.113delA; p.K38fs*25; 6:26031948-26031948

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.357T>C; p.T119T; 6:26031704-26031704

 livercarcinomaSubstitution - coding silent

c.220G>C; p.E74Q; 6:26031841-26031841

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.119_120insA; p.H40fs*59; 6:26031941-26031942

 oesophagus; lower_thirdcarcinoma; adenocarcinomaInsertion - Frameshift

c.232G>C; p.D78H; 6:26031829-26031829

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.390C>T; p.R130R; 6:26031671-26031671

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.83A>T; p.K28M; 6:26031978-26031978

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.83A>T; p.K28M; 6:26031978-26031978

 central_nervous_system; brainstemgliomaSubstitution - Missense

c.83A>T; p.K28M; 6:26031978-26031978

 central_nervous_system; brainstemglioma; astrocytoma_Grade_IIISubstitution - Missense

c.83A>T; p.K28M; 6:26031978-26031978

 central_nervous_system; brainstemgliomaSubstitution - Missense

c.83A>T; p.K28M; 6:26031978-26031978

 central_nervous_system; brainstemglioma; astrocytoma_Grade_IIISubstitution - Missense

c.83A>T; p.K28M; 6:26031978-26031978

 central_nervous_system; brainstemgliomaSubstitution - Missense

c.83A>T; p.K28M; 6:26031978-26031978

 central_nervous_system; brainstemglioma; astrocytoma_Grade_IISubstitution - Missense

c.83A>T; p.K28M; 6:26031978-26031978

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.83A>T; p.K28M; 6:26031978-26031978

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.83A>T; p.K28M; 6:26031978-26031978

 central_nervous_system; brainstemgliomaSubstitution - Missense

c.83A>T; p.K28M; 6:26031978-26031978

 central_nervous_system; brainstemgliomaSubstitution - Missense

c.83A>T; p.K28M; 6:26031978-26031978

 central_nervous_system; brainstemglioma; astrocytoma_Grade_IIISubstitution - Missense

c.83A>T; p.K28M; 6:26031978-26031978

 central_nervous_system; brainstemgliomaSubstitution - Missense

c.83A>T; p.K28M; 6:26031978-26031978

 central_nervous_system; brainstemgliomaSubstitution - Missense

c.83A>T; p.K28M; 6:26031978-26031978

 central_nervous_system; brainstemgliomaSubstitution - Missense

c.83A>T; p.K28M; 6:26031978-26031978

 central_nervous_system; brainstemglioma; astrocytoma_Grade_IVSubstitution - Missense

c.83A>T; p.K28M; 6:26031978-26031978

 central_nervous_system; brainstemglioma; astrocytoma_Grade_IISubstitution - Missense

c.83A>T; p.K28M; 6:26031978-26031978

 central_nervous_system; brainstemglioma; astrocytoma_Grade_IIISubstitution - Missense

c.83A>T; p.K28M; 6:26031978-26031978

 central_nervous_system; brainstemgliomaSubstitution - Missense

c.83A>T; p.K28M; 6:26031978-26031978

 central_nervous_system; brainstemgliomaSubstitution - Missense

c.83A>T; p.K28M; 6:26031978-26031978

 central_nervous_system; brainstemgliomaSubstitution - Missense

c.83A>T; p.K28M; 6:26031978-26031978

 central_nervous_system; brainstemglioma; astrocytoma_Grade_IIISubstitution - Missense

c.400G>A; p.E134K; 6:26031661-26031661

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.400G>A; p.E134K; 6:26031661-26031661

 skinmalignant_melanomaSubstitution - Missense

c.363G>A; p.M121I; 6:26031698-26031698

 ovaryother; neoplasmSubstitution - Missense

c.406G>A; p.A136T; 6:26031655-26031655

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; diffuse_large_B_cell_lymphomaSubstitution - Missense

c.406G>A; p.A136T; 6:26031655-26031655

 haematopoietic_and_lymphoid_tissue; central_nervous_systemlymphoid_neoplasm; primary_central_nervous_system_lymphomaSubstitution - Missense

c.406G>A; p.A136T; 6:26031655-26031655

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; diffuse_large_B_cell_lymphomaSubstitution - Missense

c.406G>A; p.A136T; 6:26031655-26031655

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; diffuse_large_B_cell_lymphomaSubstitution - Missense

c.350G>A; p.R117Q; 6:26031711-26031711

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.260G>A; p.S87N; 6:26031801-26031801

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; diffuse_large_B_cell_lymphomaSubstitution - Missense

c.227C>T; p.A76V; 6:26031834-26031834

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.259A>T; p.S87C; 6:26031802-26031802

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.313T>C; p.F105L; 6:26031748-26031748

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.313T>C; p.F105L; 6:26031748-26031748

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.316G>A; p.E106K; 6:26031745-26031745

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.316G>A; p.E106K; 6:26031745-26031745

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.258G>A; p.Q86Q; 6:26031803-26031803

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.97A>G; p.T33A; 6:26031964-26031964

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.389G>T; p.R130L; 6:26031672-26031672

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.312C>T; p.L104L; 6:26031749-26031749

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.404G>T; p.R135I; 6:26031657-26031657

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.115C>T; p.P39S; 6:26031946-26031946

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.139G>A; p.V47M; 6:26031922-26031922

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.282G>T; p.Q94H; 6:26031779-26031779

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.244G>A; p.D82N; 6:26031817-26031817

 breastcarcinomaSubstitution - Missense

c.404G>C; p.R135T; 6:26031657-26031657

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.404G>C; p.R135T; 6:26031657-26031657

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.394C>T; p.R132C; 6:26031667-26031667

 breastcarcinomaSubstitution - Missense

c.354G>A; p.V118V; 6:26031707-26031707

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.354G>A; p.V118V; 6:26031707-26031707

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - coding silent

c.250C>T; p.R84C; 6:26031811-26031811

 oesophaguscarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.284A>G; p.E95G; 6:26031777-26031777

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.354G>A; p.V118V; 6:26031707-26031707

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.370G>A; p.D124N; 6:26031691-26031691

 skinmalignant_melanomaSubstitution - Missense

c.131C>T; p.P44L; 6:26031930-26031930

 livercarcinomaSubstitution - Missense

c.131C>T; p.P44L; 6:26031930-26031930

 livercarcinomaSubstitution - Missense

c.405_406delAG; p.R135fs*>2; 6:26031655-26031656

 breastcarcinomaDeletion - Frameshift

c.153G>A; p.E51E; 6:26031908-26031908

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.153G>A; p.E51E; 6:26031908-26031908

 breastcarcinomaSubstitution - coding silent

c.258G>C; p.Q86H; 6:26031803-26031803

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

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