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Cell senescence database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

8352

Name

HIST1H3C

Synonymous

histone cluster 1, H3c;HIST1H3C;histone cluster 1, H3c

Definition

H3 histone family, member C|histone 1, H3c|histone H3.1|histone H3/c

Position

6p22.2

Gene Type

protein-coding

COSMIC somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.16C>G; p.Q6E; 6:26045426-26045426

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.368A>G; p.K123R; 6:26045778-26045778

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.16C>T; p.Q6*; 6:26045426-26045426

 large_intestinecarcinoma; adenocarcinomaSubstitution - Nonsense

c.69T>A; p.T23T; 6:26045479-26045479

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.7C>G; p.R3G; 6:26045417-26045417

 breastcarcinomaSubstitution - Missense

c.304_310delGTGGGAC; p.V102fs*>33; 6:26045714-26045720

 breastcarcinomaDeletion - Frameshift

c.7C>G; p.R3G; 6:26045417-26045417

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.366C>T; p.P122P; 6:26045776-26045776

 skinmalignant_melanomaSubstitution - coding silent

c.39C>A; p.G13G; 6:26045449-26045449

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.55A>C; p.K19Q; 6:26045465-26045465

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.225C>T; p.I75I; 6:26045635-26045635

 skinmalignant_melanomaSubstitution - coding silent

c.292G>A; p.E98K; 6:26045702-26045702

 lung; right_lower_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.292G>A; p.E98K; 6:26045702-26045702

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.292G>A; p.E98K; 6:26045702-26045702

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.250C>T; p.R84C; 6:26045660-26045660

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.88G>C; p.A30P; 6:26045498-26045498

 breastcarcinomaSubstitution - Missense

c.319G>A; p.D107N; 6:26045729-26045729

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.361A>C; p.M121L; 6:26045771-26045771

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.319G>A; p.D107N; 6:26045729-26045729

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.99C>G; p.T33T; 6:26045509-26045509

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.99C>G; p.T33T; 6:26045509-26045509

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - coding silent

c.149G>A; p.R50H; 6:26045559-26045559

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.134G>C; p.G45A; 6:26045544-26045544

 lungcarcinoma; large_cell_carcinomaSubstitution - Missense

c.10A>G; p.T4A; 6:26045420-26045420

 lung; right_lower_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.151G>A; p.E51K; 6:26045561-26045561

 NSmalignant_melanomaSubstitution - Missense

c.151G>A; p.E51K; 6:26045561-26045561

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.396_397insG; p.E134fs*>4; 6:26045806-26045807

 large_intestine; caecumcarcinoma; adenocarcinomaInsertion - Frameshift

c.184C>T; p.L62L; 6:26045594-26045594

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.160C>G; p.R54G; 6:26045570-26045570

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.32C>G; p.S11C; 6:26045442-26045442

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.220G>C; p.E74Q; 6:26045630-26045630

 oesophaguscarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.24T>C; p.A8A; 6:26045434-26045434

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.319G>C; p.D107H; 6:26045729-26045729

 pancreascarcinoma; ductal_carcinomaSubstitution - Missense

c.319G>C; p.D107H; 6:26045729-26045729

 pancreaspancreatic_intraepithelial_neoplasia_(PanIN)Substitution - Missense

c.201G>A; p.P67P; 6:26045611-26045611

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasmSubstitution - coding silent

c.348A>T; p.K116N; 6:26045758-26045758

 pancreascarcinomaSubstitution - Missense

c.83A>T; p.K28M; 6:26045493-26045493

 central_nervous_system; fourth_ventricleglioma; ependymomaSubstitution - Missense

c.276G>A; p.A92A; 6:26045686-26045686

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.101G>A; p.G34D; 6:26045511-26045511

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.122G>C; p.R41P; 6:26045532-26045532

 oesophaguscarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.292G>T; p.E98*; 6:26045702-26045702

 oesophaguscarcinomaSubstitution - Nonsense

c.379C>A; p.L127M; 6:26045789-26045789

 haematopoietic_and_lymphoid_tissue; lymph_nodelymphoid_neoplasm; diffuse_large_B_cell_lymphomaSubstitution - Missense

c.165C>T; p.Y55Y; 6:26045575-26045575

 biliary_tract; gallbladdercarcinoma; adenocarcinomaSubstitution - coding silent

c.261C>G; p.S87R; 6:26045671-26045671

 haematopoietic_and_lymphoid_tissue; lymph_nodelymphoid_neoplasm; follicular_lymphomaSubstitution - Missense

c.261C>G; p.S87R; 6:26045671-26045671

 haematopoietic_and_lymphoid_tissue; spleenlymphoid_neoplasm; diffuse_large_B_cell_lymphomaSubstitution - Missense

c.34A>G; p.T12A; 6:26045444-26045444

 lungcarcinoma; non_small_cell_carcinomaSubstitution - Missense

c.308G>A; p.G103E; 6:26045718-26045718

 skin; facecarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.161G>A; p.R54H; 6:26045571-26045571

 central_nervous_system; braingliomaSubstitution - Missense

c.66T>A; p.A22A; 6:26045476-26045476

 pancreascarcinomaSubstitution - coding silent

c.296_301delCCTACC; p.A99_L101>V; 6:26045706-26045711

 breastcarcinomaComplex - deletion inframe

c.40G>A; p.G14S; 6:26045450-26045450

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.40G>A; p.G14S; 6:26045450-26045450

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.222A>G; p.E74E; 6:26045632-26045632

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.291T>C; p.C97C; 6:26045701-26045701

 thyroidother; neoplasmSubstitution - coding silent

c.41G>A; p.G14D; 6:26045451-26045451

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.229C>A; p.Q77K; 6:26045639-26045639

 skinmalignant_melanomaSubstitution - Missense

c.110A>T; p.K37M; 6:26045520-26045520

 skinmalignant_melanomaSubstitution - Missense

c.385C>T; p.R129C; 6:26045795-26045795

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.267G>C; p.A89A; 6:26045677-26045677

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.304G>A; p.V102M; 6:26045714-26045714

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.91C>T; p.P31S; 6:26045501-26045501

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.150C>T; p.R50R; 6:26045560-26045560

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.195G>A; p.K65K; 6:26045605-26045605

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.337A>G; p.I113V; 6:26045747-26045747

 livercarcinomaSubstitution - Missense

c.92C>T; p.P31L; 6:26045502-26045502

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.59A>T; p.Q20L; 6:26045469-26045469

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.92C>T; p.P31L; 6:26045502-26045502

 skinmalignant_melanomaSubstitution - Missense

c.49C>G; p.P17A; 6:26045459-26045459

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.121C>T; p.R41C; 6:26045531-26045531

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.121C>T; p.R41C; 6:26045531-26045531

 NSNSSubstitution - Missense

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