Entrez Gene

Basic Information
Gene ID	7707
Name	ZNF148
Synonymous	zinc finger protein 148;ZNF148;zinc finger protein 148
Definition	CACCC box-binding protein\|CLL-associated antigen KW-10\|transcription factor ZBP-89\|zinc finger DNA-binding protein 89
Position	3q21
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.2208C>T; p.P736P; 3:125232518-125232518	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2281G>C; p.G761R; 3:125232445-125232445	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.982G>T; p.D328Y; 3:125233744-125233744	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.742A>G; p.T248A; 3:125234255-125234255	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.626T>C; p.I209T; 3:125277767-125277767	urinary_tract; bladder	carcinoma	Substitution - Missense
c.626T>C; p.I209T; 3:125277767-125277767	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.1254A>T; p.E418D; 3:125233472-125233472	cervix	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1191_1194delTAAG; p.S397fs*4; 3:125233532-125233535	breast	carcinoma	Deletion - Frameshift
c.1112C>T; p.S371L; 3:125233614-125233614	skin	malignant_melanoma	Substitution - Missense
c.722A>C; p.H241P; 3:125234275-125234275	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.287C>G; p.T96R; 3:125313354-125313354	cervix	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.231T>C; p.H77H; 3:125313410-125313410	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1883T>G; p.L628R; 3:125232843-125232843	thyroid	carcinoma	Substitution - Missense
c.481G>T; p.G161*; 3:125279226-125279226	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.2069delC; p.S690fs*1; 3:125232657-125232657	lung	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2301A>G; p.S767S; 3:125232425-125232425	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2200C>T; p.R734C; 3:125232526-125232526	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1423C>T; p.R475W; 3:125233303-125233303	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1423C>T; p.R475W; 3:125233303-125233303	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2310C>T; p.P770P; 3:125232416-125232416	skin	malignant_melanoma	Substitution - coding silent
c.1601_1602insA; p.N534fs*6; 3:125233124-125233125	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.372T>G; p.S124S; 3:125288190-125288190	bone; femur	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.1203G>T; p.L401L; 3:125233523-125233523	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1196G>T; p.R399I; 3:125233530-125233530	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.584G>T; p.G195V; 3:125277809-125277809	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.678A>G; p.P226P; 3:125234319-125234319	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1394A>T; p.D465V; 3:125233332-125233332	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1042C>G; p.L348V; 3:125233684-125233684	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.740G>T; p.R247I; 3:125234257-125234257	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.740G>T; p.R247I; 3:125234257-125234257	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.332C>T; p.P111L; 3:125313309-125313309	pancreas	carcinoma	Substitution - Missense
c.1541C>T; p.T514M; 3:125233185-125233185	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.972A>T; p.S324S; 3:125233754-125233754	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1058C>T; p.T353I; 3:125233668-125233668	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.1058C>T; p.T353I; 3:125233668-125233668	urinary_tract; bladder	carcinoma	Substitution - Missense
c.2201G>A; p.R734H; 3:125232525-125232525	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.1460A>T; p.Y487F; 3:125233266-125233266	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1187A>T; p.N396I; 3:125233539-125233539	skin	malignant_melanoma	Substitution - Missense
c.158C>A; p.P53H; 3:125313483-125313483	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.2052G>A; p.Q684Q; 3:125232674-125232674	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1694C>G; p.T565S; 3:125233032-125233032	breast	carcinoma; ductal_carcinoma	Substitution - Missense
c.1694C>G; p.T565S; 3:125233032-125233032	breast	carcinoma; ductal_carcinoma	Substitution - Missense
c.573C>A; p.F191L; 3:125279134-125279134	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1748C>A; p.P583Q; 3:125232978-125232978	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.959C>A; p.T320K; 3:125233767-125233767	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1427A>G; p.Y476C; 3:125233299-125233299	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2146G>C; p.E716Q; 3:125232580-125232580	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1340T>C; p.V447A; 3:125233386-125233386	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1955C>T; p.A652V; 3:125232771-125232771	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1979G>A; p.R660Q; 3:125232747-125232747	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2069_2070delCA; p.S690fs*2; 3:125232656-125232657	lung	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1894A>G; p.T632A; 3:125232832-125232832	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1528G>T; p.D510Y; 3:125233198-125233198	pancreas	NS	Substitution - Missense
c.1528G>T; p.D510Y; 3:125233198-125233198	pancreas	carcinoma	Substitution - Missense
c.563G>A; p.R188K; 3:125279144-125279144	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1912C>T; p.P638S; 3:125232814-125232814	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1455G>T; p.R485S; 3:125233271-125233271	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1039C>A; p.P347T; 3:125233687-125233687	skin	malignant_melanoma	Substitution - Missense
c.2300C>T; p.S767L; 3:125232426-125232426	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2300C>T; p.S767L; 3:125232426-125232426	breast	carcinoma; basal_(triple-negative)_carcinoma	Substitution - Missense
c.546G>A; p.T182T; 3:125279161-125279161	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.462C>T; p.I154I; 3:125279245-125279245	skin	malignant_melanoma	Substitution - coding silent
c.1087G>A; p.E363K; 3:125233639-125233639	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.462C>T; p.I154I; 3:125279245-125279245	skin	malignant_melanoma	Substitution - coding silent
c.93A>G; p.G31G; 3:125313548-125313548	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1978C>T; p.R660*; 3:125232748-125232748	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1183delA; p.I395fs*7; 3:125233543-125233543	stomach	adenocarcinoma	Deletion - Frameshift
c.304C>G; p.Q102E; 3:125313337-125313337	breast	carcinoma	Substitution - Missense
c.1393G>A; p.D465N; 3:125233333-125233333	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.1393G>A; p.D465N; 3:125233333-125233333	urinary_tract; bladder	carcinoma	Substitution - Missense
c.398A>C; p.Q133P; 3:125288164-125288164	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.545C>T; p.T182M; 3:125279162-125279162	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1400C>T; p.A467V; 3:125233326-125233326	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.609A>C; p.Q203H; 3:125277784-125277784	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.545C>T; p.T182M; 3:125279162-125279162	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2230A>C; p.I744L; 3:125232496-125232496	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1537A>G; p.T513A; 3:125233189-125233189	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1407G>T; p.Q469H; 3:125233319-125233319	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.653A>G; p.E218G; 3:125277740-125277740	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.369A>G; p.V123V; 3:125288193-125288193	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2245A>T; p.S749C; 3:125232481-125232481	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.1974C>T; p.S658S; 3:125232752-125232752	thyroid	other; neoplasm	Substitution - coding silent
c.2100A>T; p.T700T; 3:125232626-125232626	liver	carcinoma	Substitution - coding silent
c.2100A>T; p.T700T; 3:125232626-125232626	liver	carcinoma	Substitution - coding silent
c.543A>T; p.R181S; 3:125279164-125279164	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2199C>T; p.F733F; 3:125232527-125232527	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1511C>T; p.A504V; 3:125233215-125233215	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.396_397insA; p.Q133fs*27; 3:125288165-125288166	large_intestine; caecum	carcinoma; adenocarcinoma	Insertion - Frameshift
c.657G>C; p.K219N; 3:125277736-125277736	prostate	carcinoma	Substitution - Missense
c.1671G>C; p.E557D; 3:125233055-125233055	urinary_tract; bladder	carcinoma	Substitution - Missense
c.645G>A; p.Q215Q; 3:125277748-125277748	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1071T>C; p.D357D; 3:125233655-125233655	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1749G>A; p.P583P; 3:125232977-125232977	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.1856A>G; p.N619S; 3:125232870-125232870	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2193G>T; p.Q731H; 3:125232533-125232533	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.676C>G; p.P226A; 3:125234321-125234321	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1414A>G; p.K472E; 3:125233312-125233312	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1751C>G; p.S584*; 3:125232975-125232975	breast	carcinoma	Substitution - Nonsense
c.334A>C; p.I112L; 3:125288228-125288228	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1327G>C; p.D443H; 3:125233399-125233399	thyroid	carcinoma	Substitution - Missense
c.1489C>T; p.Q497*; 3:125233237-125233237	urinary_tract; bladder	carcinoma	Substitution - Nonsense
c.1184T>A; p.I395N; 3:125233542-125233542	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1913C>T; p.P638L; 3:125232813-125232813	skin	malignant_melanoma	Substitution - Missense
c.1669G>A; p.E557K; 3:125233057-125233057	cervix	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1763G>T; p.G588V; 3:125232963-125232963	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1887C>A; p.N629K; 3:125232839-125232839	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.879C>A; p.G293G; 3:125233847-125233847	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.351A>C; p.E117D; 3:125288211-125288211	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.351A>C; p.E117D; 3:125288211-125288211	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.339C>T; p.S113S; 3:125288223-125288223	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.339C>T; p.S113S; 3:125288223-125288223	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1446C>T; p.N482N; 3:125233280-125233280	skin	malignant_melanoma	Substitution - coding silent
c.2021C>T; p.S674F; 3:125232705-125232705	skin; upper_back	malignant_melanoma	Substitution - Missense
c.1257G>T; p.E419D; 3:125233469-125233469	urinary_tract; bladder	carcinoma	Substitution - Missense
c.55G>A; p.E19K; 3:125313586-125313586	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1595A>T; p.D532V; 3:125233131-125233131	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.514G>A; p.V172I; 3:125279193-125279193	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2293G>A; p.E765K; 3:125232433-125232433	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2293G>A; p.E765K; 3:125232433-125232433	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1463C>T; p.A488V; 3:125233263-125233263	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1463C>T; p.A488V; 3:125233263-125233263	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1442G>A; p.S481N; 3:125233284-125233284	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.619C>T; p.R207C; 3:125277774-125277774	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.670G>T; p.E224*; 3:125234327-125234327	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2383delT; p.*795fs?; 3:125232343-125232343	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Deletion - Frameshift
c.436C>T; p.R146W; 3:125288126-125288126	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1562A>T; p.Q521L; 3:125233164-125233164	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.2316G>T; p.V772V; 3:125232410-125232410	breast	carcinoma	Substitution - coding silent
c.2308C>T; p.P770S; 3:125232418-125232418	skin; upper_back	malignant_melanoma	Substitution - Missense
c.2308C>T; p.P770S; 3:125232418-125232418	skin	malignant_melanoma	Substitution - Missense
c.2308C>T; p.P770S; 3:125232418-125232418	skin	malignant_melanoma	Substitution - Missense
c.1738G>C; p.E580Q; 3:125232988-125232988	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.1738G>C; p.E580Q; 3:125232988-125232988	urinary_tract; bladder	carcinoma	Substitution - Missense
c.101G>T; p.G34V; 3:125313540-125313540	liver	carcinoma	Substitution - Missense
c.2199C>G; p.F733L; 3:125232527-125232527	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.101G>T; p.G34V; 3:125313540-125313540	liver	carcinoma	Substitution - Missense
c.1049C>T; p.S350F; 3:125233677-125233677	skin	malignant_melanoma	Substitution - Missense
c.2195C>A; p.P732H; 3:125232531-125232531	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2003G>T; p.R668I; 3:125232723-125232723	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1032T>G; p.D344E; 3:125233694-125233694	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1402A>G; p.M468V; 3:125233324-125233324	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; plasma_cell_myeloma	Substitution - Missense
c.142C>T; p.Q48*; 3:125313499-125313499	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.460-8delT; p.?; 3:125279255-125279255	liver	carcinoma	Unknown
c.1555G>A; p.E519K; 3:125233171-125233171	prostate	carcinoma	Substitution - Missense
c.25G>A; p.G9R; 3:125313616-125313616	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.802G>A; p.D268N; 3:125233924-125233924	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.805C>T; p.R269C; 3:125233921-125233921	skin; extremity	malignant_melanoma	Substitution - Missense
c.805C>T; p.R269C; 3:125233921-125233921	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.805C>T; p.R269C; 3:125233921-125233921	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.805C>T; p.R269C; 3:125233921-125233921	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.396delA; p.K132fs*7; 3:125288166-125288166	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.463C>T; p.L155F; 3:125279244-125279244	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.463C>T; p.L155F; 3:125279244-125279244	skin	malignant_melanoma	Substitution - Missense
c.148C>T; p.R50*; 3:125313493-125313493	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2132C>T; p.S711F; 3:125232594-125232594	breast	carcinoma	Substitution - Missense
c.120A>G; p.G40G; 3:125313521-125313521	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1705T>C; p.S569P; 3:125233021-125233021	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.1128G>A; p.S376S; 3:125233598-125233598	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent

COSMIC somatic mutation [Top]