Entrez Gene

Basic Information
Gene ID	7314
Name	UBB
Synonymous	ubiquitin B;UBB;ubiquitin B
Definition	polyubiquitin B\|polyubiquitin-B
Position	17p12-p11.2
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.67A>C; p.I23L; 17:16381974-16381974	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.460C>A; p.Q154K; 17:16382367-16382367	urinary_tract; bladder	carcinoma	Substitution - Missense
c.270C>T; p.T90T; 17:16382177-16382177	skin	malignant_melanoma	Substitution - coding silent
c.270C>T; p.T90T; 17:16382177-16382177	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.270C>T; p.T90T; 17:16382177-16382177	central_nervous_system; brain	glioma	Substitution - coding silent
c.368G>A; p.G123D; 17:16382275-16382275	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.534G>A; p.V178V; 17:16382441-16382441	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.160C>T; p.R54C; 17:16382067-16382067	skin; upper_arm	malignant_melanoma	Substitution - Missense
c.321G>A; p.Q107Q; 17:16382228-16382228	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.93G>T; p.Q31H; 17:16382000-16382000	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.390C>T; p.R130R; 17:16382297-16382297	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.140G>T; p.G47V; 17:16382047-16382047	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.388C>T; p.R130C; 17:16382295-16382295	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.383A>G; p.D128G; 17:16382290-16382290	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.258C>T; p.G86G; 17:16382165-16382165	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.690A>G; p.230; 17:16382597-16382597	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.569C>A; p.P190H; 17:16382476-16382476	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.360C>T; p.I120I; 17:16382267-16382267	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.276A>G; p.E92E; 17:16382183-16382183	skin	malignant_melanoma	Substitution - coding silent
c.276A>G; p.E92E; 17:16382183-16382183	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.276A>G; p.E92E; 17:16382183-16382183	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.276A>G; p.E92E; 17:16382183-16382183	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.276A>G; p.E92E; 17:16382183-16382183	NS	malignant_melanoma	Substitution - coding silent
c.276A>G; p.E92E; 17:16382183-16382183	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma; large_cell	Substitution - coding silent
c.276A>G; p.E92E; 17:16382183-16382183	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.276A>G; p.E92E; 17:16382183-16382183	skin	malignant_melanoma	Substitution - coding silent
c.276A>G; p.E92E; 17:16382183-16382183	skin	malignant_melanoma	Substitution - coding silent
c.267C>T; p.I89I; 17:16382174-16382174	breast	carcinoma	Substitution - coding silent
c.363T>C; p.F121F; 17:16382270-16382270	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.617G>A; p.R206H; 17:16382524-16382524	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.255C>G; p.T85T; 17:16382162-16382162	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - coding silent
c.671G>A; p.R224H; 17:16382578-16382578	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.328G>T; p.E110*; 17:16382235-16382235	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.162T>C; p.R54R; 17:16382069-16382069	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.162T>C; p.R54R; 17:16382069-16382069	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.162T>C; p.R54R; 17:16382069-16382069	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.567C>T; p.P189P; 17:16382474-16382474	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.567C>T; p.P189P; 17:16382474-16382474	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.567C>T; p.P189P; 17:16382474-16382474	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.567C>T; p.P189P; 17:16382474-16382474	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.143A>T; p.K48M; 17:16382050-16382050	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.143A>T; p.K48M; 17:16382050-16382050	skin; upper_arm	malignant_melanoma	Substitution - Missense
c.684C>T; p.G228G; 17:16382591-16382591	ovary	other; neoplasm	Substitution - coding silent
c.339T>C; p.P113P; 17:16382246-16382246	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.339T>C; p.P113P; 17:16382246-16382246	skin	malignant_melanoma	Substitution - coding silent
c.339T>C; p.P113P; 17:16382246-16382246	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.70G>A; p.E24K; 17:16381977-16381977	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.70G>A; p.E24K; 17:16381977-16381977	urinary_tract; bladder	carcinoma	Substitution - Missense
c.150G>A; p.L50L; 17:16382057-16382057	skin; upper_arm	malignant_melanoma	Substitution - coding silent
c.441G>A; p.L147L; 17:16382348-16382348	bone; pelvis	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.232C>A; p.Q78K; 17:16382139-16382139	urinary_tract; bladder	carcinoma	Substitution - Missense
c.564delC; p.D191fs*35; 17:16382471-16382471	stomach	carcinoma; intestinal_adenocarcinoma	Deletion - Frameshift
c.564delC; p.D191fs*35; 17:16382471-16382471	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.564delC; p.D191fs*35; 17:16382471-16382471	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift

COSMIC somatic mutation [Top]