| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 6648 |
Name | SOD2 |
Synonymous | superoxide dismutase 2, mitochondrial;SOD2;superoxide dismutase 2, mitochondrial |
Definition | Mn superoxide dismutase|indophenoloxidase B|manganese-containing superoxide dismutase|mangano-superoxide dismutase|superoxide dismutase [Mn], mitochondrial |
Position | 6q25.3 |
Gene Type | protein-coding |
COSMIC somatic mutation [Top] | |||
Mutation (CDS; AA; Chr) | Site | Histology | Mutation Type |
|---|---|---|---|
c.367C>T; p.R123C; 6:159685010-159685010 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.47T>C; p.V16A; 6:159692840-159692840 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.520A>G; p.T174A; 6:159684857-159684857 |
kidney | carcinoma; clear_cell_renal_cell_carcinoma | Substitution - Missense |
c.19T>C; p.C7R; 6:159693149-159693149 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.324C>T; p.N108N; 6:159688145-159688145 |
breast | carcinoma | Substitution - coding silent |
c.329G>A; p.G110D; 6:159688140-159688140 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |
c.527T>G; p.L176R; 6:159682635-159682635 |
lung | carcinoma; adenocarcinoma | Substitution - Missense |
c.416C>T; p.S139F; 6:159684961-159684961 |
haematopoietic_and_lymphoid_tissue | lymphoid_neoplasm; mantle_cell_lymphoma | Substitution - Missense |
c.416C>T; p.S139F; 6:159684961-159684961 |
skin; scalp | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.368G>A; p.R123H; 6:159685009-159685009 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.426C>A; p.V142V; 6:159684951-159684951 |
large_intestine; rectum | carcinoma; adenocarcinoma | Substitution - coding silent |
c.493C>G; p.P165A; 6:159684884-159684884 |
oesophagus | carcinoma; adenocarcinoma | Substitution - Missense |
c.581A>C; p.K194T; 6:159682581-159682581 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.571C>A; p.L191I; 6:159682591-159682591 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.229G>A; p.D77N; 6:159688240-159688240 |
large_intestine; caecum | carcinoma; adenocarcinoma | Substitution - Missense |
c.199_201delGAG; p.E67delE; 6:159692686-159692688 |
stomach | carcinoma; intestinal_adenocarcinoma | Deletion - In frame |
c.421G>T; p.G141C; 6:159684956-159684956 |
lung | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.409G>A; p.A137T; 6:159684968-159684968 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.330T>G; p.G110G; 6:159688139-159688139 |
bone; fibula | Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | Substitution - coding silent |
c.171C>A; p.A57A; 6:159692716-159692716 |
kidney | carcinoma; clear_cell_renal_cell_carcinoma | Substitution - coding silent |
c.288C>T; p.I96I; 6:159688181-159688181 |
biliary_tract; gallbladder | carcinoma; adenocarcinoma | Substitution - coding silent |
c.318C>T; p.S106S; 6:159688151-159688151 |
large_intestine | carcinoma; adenocarcinoma | Substitution - coding silent |
c.243G>A; p.Q81Q; 6:159688226-159688226 |
urinary_tract; bladder | carcinoma | Substitution - coding silent |
c.243G>A; p.Q81Q; 6:159688226-159688226 |
urinary_tract; bladder | carcinoma; transitional_cell_carcinoma | Substitution - coding silent |
c.138C>T; p.I46I; 6:159692749-159692749 |
oesophagus | carcinoma; adenocarcinoma | Substitution - coding silent |
c.558G>T; p.E186D; 6:159682604-159682604 |
central_nervous_system; brain | primitive_neuroectodermal_tumour-medulloblastoma | Substitution - Missense |